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- W2015120885 abstract "Some of Geranium species (Cranesbill). used in traditional medicine as antidiabetic, hemostatic, stomachic, antihemorrhoidal, antidiarrheic and treatment of pain, fevers and gastrointestinal disorders [1,2]. Inhibitory effect of different extracts of G. lasiopus on H2O2-induced lipid peroxidation in human red blood cells was investigated. Chromatographic studies on the EtOAc fraction of G. lasiopus lead to the isolation of 8 flavonoids (kaempferol, quercetin, quercetin 3-O-β-glucopyranoside, quercetin 3-O-β-galactopyranoside, kaempferol 3-O-α-rhamnosyl(1→6)-β-glucopyranoside, quercetin 3-O-α-rhamnosyl(1→6)-β-glucopyranoside, kaempferol 3-O-α-rhamnosyl(1→2)-β-glucopyranoside and quercetin 3-O-α-rhamnosyl(1→2)-β-glucopyranoside), 2 phenols (gallic acide and it' s methyl ester) and a hydrolzable tannin 1-O-galloyl-3, 6- hexahydroxydiphenoyl-α-galactopyranoside). The structures of the compounds were elucidated by 1- and 2- dimensional NMR techniques (1H, 13C, COSY, HMBC, HMQC and NOESY) and ESI-TOF-Mass spectrometry. All compounds have shown comparable or higher activity than that of ascorbic acide and trolox which were used as control substances. Quercetin 3-O-β-galactopyranoside was found to be the most active compound at 50µg/ml (70.23% inhibition). Results of the present study partially explain the use of cranesbill for the treatment of gastrointestinal illness, pain and fevers associated with oxidative stress." @default.
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- W2015120885 date "2008-07-01" @default.
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- W2015120885 title "Antioxidant polyphenolic compounds from Geranium lasiopus Boiss. et Heldr" @default.
- W2015120885 doi "https://doi.org/10.1055/s-0028-1084391" @default.
- W2015120885 hasPublicationYear "2008" @default.
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