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• W2015149511 abstract "Reproductive hormonal characteristics are a primary influence on the acquisition and maintenance of peak bone mass such that events associated with the reproductive life span and procreation have profound effects on subsequent risk for osteoporosis and fractures. A longer duration of menstruation, either from earlier menarche or later menopause, and the use of estrogen-containing hormonal contraception appear to increase bone mineral density and may reduce fracture risk. Pregnancy and lactation increase bone turnover and decrease bone density, but the effect is subsequently reversed with recovery of density and possible reduction in long-term fracture risk. Conditions that induce amenorrhea or early menopause, and nonestrogen-containing hormonal contraceptives such as depot medroxyprogesterone acetate, are associated with decreased bone density and possibly increased fracture risk. Mechanisms mediating these known or suggested effects are incompletely characterized." @default.
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• W2015149511 date "1987-01-01" @default.
• W2015149511 modified "2023-09-27" @default.
• W2015149511 title "Endocrine aspects of lactation and postpartum infertility" @default.
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• W2015149511 doi "https://doi.org/10.1016/0022-4731(87)90185-3" @default.
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