Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015156524> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2015156524 endingPage "393" @default.
- W2015156524 startingPage "380" @default.
- W2015156524 abstract "The monoclonal antibody (MAb) 1BE12 has recently been reported to react with several human normal and abnormal tissues. In human endometrium, it reacts more strongly with carcinomas than with normal tissue. To investigate the effectiveness of MAb 1BE12 in identifying cell proliferation in human endometrial cancers, 1BE12 immunocytochemical assays (ICAs) were performed on frozen (n = 47) and paraffin (n = 100) sections with subsequent computer-assisted microcytophotometric (SAMBA) evaluation of immunopre- cipitate distribution. MAb IBE12 immunoreactivity was not impaired by tissue fixation and paraffin embedding. It reacted with normal proliferative endom- etrium but not with normal secretory endometrium, and immunoreactivity increased with the degree of cell proliferation and malignancy, the amount of immunostaining being greater in invasive carcinomas than in normal proliferative endometrium and endometrial hyperplasia. ICAs showed no correlation between MAb 1BE12 immunoreactivity and estrogen and progesterone receptor antigenic sites. On the other hand, MAb 1BE12 staining in frozen sections increased with Ki67, EGFR, pHER-2/neu, and cathepsin immunostaining. These findings suggest that ICAs on frozen and paraffin-embedded biopsy specimens using MAb 1BE12 along with other markers can be useful for early detection and grading of endometrial carcinoma. The relevance of MAb 1BEI2 to the selection of patients for laser ablation of the endometrium rather than hysterectomy is also discussed." @default.
- W2015156524 created "2016-06-24" @default.
- W2015156524 creator A5009133407 @default.
- W2015156524 creator A5018937682 @default.
- W2015156524 creator A5041015671 @default.
- W2015156524 creator A5042154346 @default.
- W2015156524 creator A5048568279 @default.
- W2015156524 creator A5069748601 @default.
- W2015156524 creator A5071065958 @default.
- W2015156524 creator A5090545095 @default.
- W2015156524 date "1991-10-01" @default.
- W2015156524 modified "2023-09-26" @default.
- W2015156524 title "Monoclonal Antibody 1BE12 Immunoreactivity With Human Endometrium" @default.
- W2015156524 doi "https://doi.org/10.1097/00004347-199110000-00011" @default.
- W2015156524 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1774109" @default.
- W2015156524 hasPublicationYear "1991" @default.
- W2015156524 type Work @default.
- W2015156524 sameAs 2015156524 @default.
- W2015156524 citedByCount "3" @default.
- W2015156524 crossrefType "journal-article" @default.
- W2015156524 hasAuthorship W2015156524A5009133407 @default.
- W2015156524 hasAuthorship W2015156524A5018937682 @default.
- W2015156524 hasAuthorship W2015156524A5041015671 @default.
- W2015156524 hasAuthorship W2015156524A5042154346 @default.
- W2015156524 hasAuthorship W2015156524A5048568279 @default.
- W2015156524 hasAuthorship W2015156524A5069748601 @default.
- W2015156524 hasAuthorship W2015156524A5071065958 @default.
- W2015156524 hasAuthorship W2015156524A5090545095 @default.
- W2015156524 hasConcept C134018914 @default.
- W2015156524 hasConcept C142724271 @default.
- W2015156524 hasConcept C147483822 @default.
- W2015156524 hasConcept C159654299 @default.
- W2015156524 hasConcept C203014093 @default.
- W2015156524 hasConcept C204232928 @default.
- W2015156524 hasConcept C2775904963 @default.
- W2015156524 hasConcept C2777546739 @default.
- W2015156524 hasConcept C2779484032 @default.
- W2015156524 hasConcept C2779742232 @default.
- W2015156524 hasConcept C4224716 @default.
- W2015156524 hasConcept C542903549 @default.
- W2015156524 hasConcept C71924100 @default.
- W2015156524 hasConcept C86803240 @default.
- W2015156524 hasConcept C95798472 @default.
- W2015156524 hasConceptScore W2015156524C134018914 @default.
- W2015156524 hasConceptScore W2015156524C142724271 @default.
- W2015156524 hasConceptScore W2015156524C147483822 @default.
- W2015156524 hasConceptScore W2015156524C159654299 @default.
- W2015156524 hasConceptScore W2015156524C203014093 @default.
- W2015156524 hasConceptScore W2015156524C204232928 @default.
- W2015156524 hasConceptScore W2015156524C2775904963 @default.
- W2015156524 hasConceptScore W2015156524C2777546739 @default.
- W2015156524 hasConceptScore W2015156524C2779484032 @default.
- W2015156524 hasConceptScore W2015156524C2779742232 @default.
- W2015156524 hasConceptScore W2015156524C4224716 @default.
- W2015156524 hasConceptScore W2015156524C542903549 @default.
- W2015156524 hasConceptScore W2015156524C71924100 @default.
- W2015156524 hasConceptScore W2015156524C86803240 @default.
- W2015156524 hasConceptScore W2015156524C95798472 @default.
- W2015156524 hasIssue "4" @default.
- W2015156524 hasLocation W20151565241 @default.
- W2015156524 hasLocation W20151565242 @default.
- W2015156524 hasOpenAccess W2015156524 @default.
- W2015156524 hasPrimaryLocation W20151565241 @default.
- W2015156524 hasRelatedWork W1915348805 @default.
- W2015156524 hasRelatedWork W1974516972 @default.
- W2015156524 hasRelatedWork W2011115754 @default.
- W2015156524 hasRelatedWork W2015156524 @default.
- W2015156524 hasRelatedWork W2067097521 @default.
- W2015156524 hasRelatedWork W2074123101 @default.
- W2015156524 hasRelatedWork W2389831003 @default.
- W2015156524 hasRelatedWork W2398317084 @default.
- W2015156524 hasRelatedWork W2410258605 @default.
- W2015156524 hasRelatedWork W4250965677 @default.
- W2015156524 hasVolume "10" @default.
- W2015156524 isParatext "false" @default.
- W2015156524 isRetracted "false" @default.
- W2015156524 magId "2015156524" @default.
- W2015156524 workType "article" @default.