FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015159733> ?p ?o ?g. }

• W2015159733 endingPage "11890" @default.
• W2015159733 startingPage "11886" @default.
• W2015159733 abstract "Inspite of several stimulating developments in gene therapy, the formulation of a targeted gene delivery vector is still far from ideal. We have demonstrated the potential of reconstituted Sendai viral envelopes containing only the fusion glycoprotein (F-virosomes) in targeted delivery of reporter genes to liver cells of BALB/c mouse in vivo. The membrane fusion-mediated high efficiency of gene transfer to liver cells was ascertained following a critical evaluation of the level of the DNA, mRNA, and relevant proteins. Furthermore, the involvement of viral glycoprotein both as a unique natural ligand and as a membrane fusogen could lead to preferential transfection of parenchymal cell types of liver. The integration of transgenes in the mouse chromosomal DNA and its stable expression up to 4 mo after single i.v. administration of this gene carrier has bolstered its efficiency and novelty. Moreover, the F-virosomes did not elicit significant humoral immune response against the fusion protein in the injected animal. The findings reported here open up the possibility for considering F-virosomes as a promising vehicle for site-specific DNA delivery in gene therapy." @default.
• W2015159733 created "2016-06-24" @default.
• W2015159733 creator A5005971403 @default.
• W2015159733 creator A5020779635 @default.
• W2015159733 creator A5033375254 @default.
• W2015159733 creator A5079286294 @default.
• W2015159733 creator A5080808334 @default.
• W2015159733 date "1998-09-29" @default.
• W2015159733 modified "2023-10-01" @default.
• W2015159733 title "Site-specific gene delivery <i>in vivo</i> through engineered Sendai viral envelopes" @default.
• W2015159733 cites W1480671701 @default.
• W2015159733 cites W1489436358 @default.
• W2015159733 cites W1522128121 @default.
• W2015159733 cites W1616824889 @default.
• W2015159733 cites W1914528802 @default.
• W2015159733 cites W1980179914 @default.
• W2015159733 cites W1989787607 @default.
• W2015159733 cites W2005001697 @default.
• W2015159733 cites W2011659579 @default.
• W2015159733 cites W2013224456 @default.
• W2015159733 cites W2017348860 @default.
• W2015159733 cites W2021917788 @default.
• W2015159733 cites W2073537725 @default.
• W2015159733 cites W2077801336 @default.
• W2015159733 cites W2083676937 @default.
• W2015159733 cites W2097794242 @default.
• W2015159733 cites W2123958462 @default.
• W2015159733 cites W2155527842 @default.
• W2015159733 cites W2413456745 @default.
• W2015159733 cites W4254188257 @default.
• W2015159733 doi "https://doi.org/10.1073/pnas.95.20.11886" @default.
• W2015159733 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/21735" @default.
• W2015159733 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9751760" @default.
• W2015159733 hasPublicationYear "1998" @default.
• W2015159733 type Work @default.
• W2015159733 sameAs 2015159733 @default.
• W2015159733 citedByCount "48" @default.
• W2015159733 countsByYear W20151597332012 @default.
• W2015159733 countsByYear W20151597332013 @default.
• W2015159733 countsByYear W20151597332017 @default.
• W2015159733 countsByYear W20151597332018 @default.
• W2015159733 countsByYear W20151597332019 @default.
• W2015159733 countsByYear W20151597332020 @default.
• W2015159733 countsByYear W20151597332022 @default.
• W2015159733 countsByYear W20151597332023 @default.
• W2015159733 crossrefType "journal-article" @default.
• W2015159733 hasAuthorship W2015159733A5005971403 @default.
• W2015159733 hasAuthorship W2015159733A5020779635 @default.
• W2015159733 hasAuthorship W2015159733A5033375254 @default.
• W2015159733 hasAuthorship W2015159733A5079286294 @default.
• W2015159733 hasAuthorship W2015159733A5080808334 @default.
• W2015159733 hasBestOaLocation W20151597332 @default.
• W2015159733 hasConcept C104317684 @default.
• W2015159733 hasConcept C111599444 @default.
• W2015159733 hasConcept C111829193 @default.
• W2015159733 hasConcept C135983454 @default.
• W2015159733 hasConcept C150194340 @default.
• W2015159733 hasConcept C153911025 @default.
• W2015159733 hasConcept C159047783 @default.
• W2015159733 hasConcept C161733203 @default.
• W2015159733 hasConcept C167508917 @default.
• W2015159733 hasConcept C203014093 @default.
• W2015159733 hasConcept C207001950 @default.
• W2015159733 hasConcept C2522874641 @default.
• W2015159733 hasConcept C2780127873 @default.
• W2015159733 hasConcept C2780801004 @default.
• W2015159733 hasConcept C32470452 @default.
• W2015159733 hasConcept C40767141 @default.
• W2015159733 hasConcept C54009773 @default.
• W2015159733 hasConcept C54355233 @default.
• W2015159733 hasConcept C55493867 @default.
• W2015159733 hasConcept C86803240 @default.
• W2015159733 hasConcept C8891405 @default.
• W2015159733 hasConcept C95444343 @default.
• W2015159733 hasConceptScore W2015159733C104317684 @default.
• W2015159733 hasConceptScore W2015159733C111599444 @default.
• W2015159733 hasConceptScore W2015159733C111829193 @default.
• W2015159733 hasConceptScore W2015159733C135983454 @default.
• W2015159733 hasConceptScore W2015159733C150194340 @default.
• W2015159733 hasConceptScore W2015159733C153911025 @default.
• W2015159733 hasConceptScore W2015159733C159047783 @default.
• W2015159733 hasConceptScore W2015159733C161733203 @default.
• W2015159733 hasConceptScore W2015159733C167508917 @default.
• W2015159733 hasConceptScore W2015159733C203014093 @default.
• W2015159733 hasConceptScore W2015159733C207001950 @default.
• W2015159733 hasConceptScore W2015159733C2522874641 @default.
• W2015159733 hasConceptScore W2015159733C2780127873 @default.
• W2015159733 hasConceptScore W2015159733C2780801004 @default.
• W2015159733 hasConceptScore W2015159733C32470452 @default.
• W2015159733 hasConceptScore W2015159733C40767141 @default.
• W2015159733 hasConceptScore W2015159733C54009773 @default.
• W2015159733 hasConceptScore W2015159733C54355233 @default.
• W2015159733 hasConceptScore W2015159733C55493867 @default.
• W2015159733 hasConceptScore W2015159733C86803240 @default.
• W2015159733 hasConceptScore W2015159733C8891405 @default.
• W2015159733 hasConceptScore W2015159733C95444343 @default.
• W2015159733 hasIssue "20" @default.
• W2015159733 hasLocation W20151597331 @default.

• next