Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015160977> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2015160977 abstract "We have detected trans-acting factors that regulate developmental hemoglobin switching by fusing erythroid cells of different developmental programs. Adult erythroid cells of one anuran species, Xenopus laevis, were fused with tadpole erythroid cells of another frog, Rana catesbeiana. In a second set of experiments, dimethyl sulfoxide-induced murine erythroleukemia cells, which express only adult mouse globins, were fused with Rana tadpole erythroid cells, which express only embryonic and fetal-like globins. Adult Rana globin gene expression was detected in both sets of transient heterokaryons at 6 hr after fusion. Dot blots and Northern blots of total RNA from the heterokaryons contained material that reacted with an adult Rana alpha-globin probe; newly synthesized adult Rana hemoglobin tetramers were detected with native polyacrylamide gel electrophoresis. These results show that developmental stage-specific transacting factors for globin genes can function across vertebrate classes (mammalia to amphibia) and suggest that the mechanisms that regulate developmental hemoglobin switching are highly conserved." @default.
- W2015160977 created "2016-06-24" @default.
- W2015160977 creator A5009788081 @default.
- W2015160977 creator A5046734297 @default.
- W2015160977 creator A5053535551 @default.
- W2015160977 creator A5059195451 @default.
- W2015160977 creator A5071314588 @default.
- W2015160977 creator A5076828739 @default.
- W2015160977 date "1989-05-01" @default.
- W2015160977 modified "2023-09-27" @default.
- W2015160977 title "Intracellular signals for developmental hemoglobin switching" @default.
- W2015160977 cites W1565023713 @default.
- W2015160977 cites W1664124560 @default.
- W2015160977 cites W1867261337 @default.
- W2015160977 cites W1964725018 @default.
- W2015160977 cites W1967955605 @default.
- W2015160977 cites W196861196 @default.
- W2015160977 cites W1972984824 @default.
- W2015160977 cites W1975990934 @default.
- W2015160977 cites W1977041798 @default.
- W2015160977 cites W1978127297 @default.
- W2015160977 cites W1979692126 @default.
- W2015160977 cites W1994970763 @default.
- W2015160977 cites W1998635685 @default.
- W2015160977 cites W2004439271 @default.
- W2015160977 cites W2014669590 @default.
- W2015160977 cites W2024866452 @default.
- W2015160977 cites W2027242485 @default.
- W2015160977 cites W2043986824 @default.
- W2015160977 cites W2070959011 @default.
- W2015160977 cites W2072304237 @default.
- W2015160977 cites W2075230808 @default.
- W2015160977 cites W2088024524 @default.
- W2015160977 cites W2094339131 @default.
- W2015160977 cites W2118299921 @default.
- W2015160977 cites W2126539287 @default.
- W2015160977 cites W2134812217 @default.
- W2015160977 cites W2333665136 @default.
- W2015160977 cites W4250839699 @default.
- W2015160977 doi "https://doi.org/10.1016/0012-1606(89)90317-5" @default.
- W2015160977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2785064" @default.
- W2015160977 hasPublicationYear "1989" @default.
- W2015160977 type Work @default.
- W2015160977 sameAs 2015160977 @default.
- W2015160977 citedByCount "5" @default.
- W2015160977 crossrefType "journal-article" @default.
- W2015160977 hasAuthorship W2015160977A5009788081 @default.
- W2015160977 hasAuthorship W2015160977A5046734297 @default.
- W2015160977 hasAuthorship W2015160977A5053535551 @default.
- W2015160977 hasAuthorship W2015160977A5059195451 @default.
- W2015160977 hasAuthorship W2015160977A5071314588 @default.
- W2015160977 hasAuthorship W2015160977A5076828739 @default.
- W2015160977 hasConcept C104317684 @default.
- W2015160977 hasConcept C105702510 @default.
- W2015160977 hasConcept C109214941 @default.
- W2015160977 hasConcept C121332964 @default.
- W2015160977 hasConcept C125996951 @default.
- W2015160977 hasConcept C153911025 @default.
- W2015160977 hasConcept C2778311813 @default.
- W2015160977 hasConcept C2778917026 @default.
- W2015160977 hasConcept C2779535977 @default.
- W2015160977 hasConcept C2781130464 @default.
- W2015160977 hasConcept C54355233 @default.
- W2015160977 hasConcept C55493867 @default.
- W2015160977 hasConcept C85265743 @default.
- W2015160977 hasConcept C86803240 @default.
- W2015160977 hasConcept C95444343 @default.
- W2015160977 hasConceptScore W2015160977C104317684 @default.
- W2015160977 hasConceptScore W2015160977C105702510 @default.
- W2015160977 hasConceptScore W2015160977C109214941 @default.
- W2015160977 hasConceptScore W2015160977C121332964 @default.
- W2015160977 hasConceptScore W2015160977C125996951 @default.
- W2015160977 hasConceptScore W2015160977C153911025 @default.
- W2015160977 hasConceptScore W2015160977C2778311813 @default.
- W2015160977 hasConceptScore W2015160977C2778917026 @default.
- W2015160977 hasConceptScore W2015160977C2779535977 @default.
- W2015160977 hasConceptScore W2015160977C2781130464 @default.
- W2015160977 hasConceptScore W2015160977C54355233 @default.
- W2015160977 hasConceptScore W2015160977C55493867 @default.
- W2015160977 hasConceptScore W2015160977C85265743 @default.
- W2015160977 hasConceptScore W2015160977C86803240 @default.
- W2015160977 hasConceptScore W2015160977C95444343 @default.
- W2015160977 hasLocation W20151609771 @default.
- W2015160977 hasLocation W20151609772 @default.
- W2015160977 hasOpenAccess W2015160977 @default.
- W2015160977 hasPrimaryLocation W20151609771 @default.
- W2015160977 hasRelatedWork W1500632049 @default.
- W2015160977 hasRelatedWork W1773597356 @default.
- W2015160977 hasRelatedWork W1982555018 @default.
- W2015160977 hasRelatedWork W1998574570 @default.
- W2015160977 hasRelatedWork W2015160977 @default.
- W2015160977 hasRelatedWork W2064756422 @default.
- W2015160977 hasRelatedWork W2187419957 @default.
- W2015160977 hasRelatedWork W2400170985 @default.
- W2015160977 hasRelatedWork W2887929323 @default.
- W2015160977 hasRelatedWork W4231950389 @default.
- W2015160977 isParatext "false" @default.
- W2015160977 isRetracted "false" @default.
- W2015160977 magId "2015160977" @default.
- W2015160977 workType "article" @default.