FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015161791> ?p ?o ?g. }

• W2015161791 endingPage "203" @default.
• W2015161791 startingPage "191" @default.
• W2015161791 abstract "Cells must be able to maintain their intracellular homeostasis in the face of changing conditions. Typically, they respond by invoking complex regulatory mechanisms, including a global inhibition of translation. This reduction in protein synthesis may prevent continued gene expression during potentially error-prone conditions as well as allow for the turnover of existing mRNAs and proteins, whilst gene expression is directed toward the production of new molecules required to protect against or detoxify the stress. However, it is becoming increasingly recognized that not all translation is inhibited and translational control of specific mRNAs is required for survival under stress conditions. Control of protein levels via translational regulation offers a significant advantage to the cell due to the immediacy of the regulatory effect. This review describes how protein synthesis is regulated in response to oxidative stress conditions induced by exposure to hydrogen peroxide. Translational control can be mediated via direct oxidative regulation of translation factors as well via mRNA-specific regulatory mechanisms. Additionally, increasing evidence suggests that oxidative damage to the translational apparatus can itself alter the proteomic output. The resulting translational reprogramming is fundamental for adaptation to the oxidative stress. Antioxid. Redox Signal. 15, 191–203." @default.
• W2015161791 created "2016-06-24" @default.
• W2015161791 creator A5070645740 @default.
• W2015161791 date "2011-07-01" @default.
• W2015161791 modified "2023-10-16" @default.
• W2015161791 title "Regulation of Translation by Hydrogen Peroxide" @default.
• W2015161791 cites W1503622815 @default.
• W2015161791 cites W1520541928 @default.
• W2015161791 cites W1532227683 @default.
• W2015161791 cites W1546139069 @default.
• W2015161791 cites W1560901632 @default.
• W2015161791 cites W1583656960 @default.
• W2015161791 cites W1587891756 @default.
• W2015161791 cites W1719011723 @default.
• W2015161791 cites W1752358945 @default.
• W2015161791 cites W1964221844 @default.
• W2015161791 cites W1965933116 @default.
• W2015161791 cites W1968678331 @default.
• W2015161791 cites W1969125983 @default.
• W2015161791 cites W1969995127 @default.
• W2015161791 cites W1974241302 @default.
• W2015161791 cites W1975973558 @default.
• W2015161791 cites W1980438612 @default.
• W2015161791 cites W1982738524 @default.
• W2015161791 cites W1983814322 @default.
• W2015161791 cites W1988299219 @default.
• W2015161791 cites W1990146329 @default.
• W2015161791 cites W1991017037 @default.
• W2015161791 cites W1991185908 @default.
• W2015161791 cites W2002617338 @default.
• W2015161791 cites W2002930228 @default.
• W2015161791 cites W2004685815 @default.
• W2015161791 cites W2008020214 @default.
• W2015161791 cites W2008329852 @default.
• W2015161791 cites W2008410413 @default.
• W2015161791 cites W2009969516 @default.
• W2015161791 cites W2010250072 @default.
• W2015161791 cites W2015392958 @default.
• W2015161791 cites W2018477176 @default.
• W2015161791 cites W2023706819 @default.
• W2015161791 cites W2024544617 @default.
• W2015161791 cites W2025251808 @default.
• W2015161791 cites W2026566929 @default.
• W2015161791 cites W2027694461 @default.
• W2015161791 cites W2028866472 @default.
• W2015161791 cites W2031269330 @default.
• W2015161791 cites W2035205542 @default.
• W2015161791 cites W2035667407 @default.
• W2015161791 cites W2041034033 @default.
• W2015161791 cites W2042741874 @default.
• W2015161791 cites W2043322219 @default.
• W2015161791 cites W2046385725 @default.
• W2015161791 cites W2046445620 @default.
• W2015161791 cites W2048551040 @default.
• W2015161791 cites W2049128728 @default.
• W2015161791 cites W2056568168 @default.
• W2015161791 cites W2058913657 @default.
• W2015161791 cites W2059710944 @default.
• W2015161791 cites W2062195516 @default.
• W2015161791 cites W2065129644 @default.
• W2015161791 cites W2075511135 @default.
• W2015161791 cites W2076120836 @default.
• W2015161791 cites W2078128181 @default.
• W2015161791 cites W2079051847 @default.
• W2015161791 cites W2079310705 @default.
• W2015161791 cites W2081764750 @default.
• W2015161791 cites W2084109336 @default.
• W2015161791 cites W2084297010 @default.
• W2015161791 cites W2086939601 @default.
• W2015161791 cites W2089330117 @default.
• W2015161791 cites W2092279282 @default.
• W2015161791 cites W2093131295 @default.
• W2015161791 cites W2095078840 @default.
• W2015161791 cites W2096712245 @default.
• W2015161791 cites W2097224528 @default.
• W2015161791 cites W2099377713 @default.
• W2015161791 cites W2100428689 @default.
• W2015161791 cites W2103158227 @default.
• W2015161791 cites W2106151456 @default.
• W2015161791 cites W2108926627 @default.
• W2015161791 cites W2109140791 @default.
• W2015161791 cites W2109535551 @default.
• W2015161791 cites W2110098472 @default.
• W2015161791 cites W2114474174 @default.
• W2015161791 cites W2115692661 @default.
• W2015161791 cites W2115897170 @default.
• W2015161791 cites W2116125649 @default.
• W2015161791 cites W2118337893 @default.
• W2015161791 cites W2118900588 @default.
• W2015161791 cites W2121035779 @default.
• W2015161791 cites W2121401282 @default.
• W2015161791 cites W2121596680 @default.
• W2015161791 cites W2127848114 @default.
• W2015161791 cites W2128677683 @default.
• W2015161791 cites W2129320411 @default.
• W2015161791 cites W2130326770 @default.
• W2015161791 cites W2131632095 @default.
• W2015161791 cites W2134224359 @default.

• next