FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015162868> ?p ?o ?g. }

• W2015162868 endingPage "877" @default.
• W2015162868 startingPage "866" @default.
• W2015162868 abstract "Las moléculas de adhesión celular (MAC) desempeñan un papel fundamental en la localización de los linfocitos T en la piel. El presente estudio cuantifica la expresión de MAC en pacientes con linfoma cutáneo de células T (LCCT) y lo compara con la observada en otras dermatosis. Se dispuso de material congelado de 42 pacientes distribuidos en 5 grupos: LCCT iniciales, micosis fungoide en fase de mácula y placa (11 pacientes); LCCT avanzados (n=7): micosis fungoide y síndrome de Sézary; enfermedades cutáneas inflamatorias (n=12): psoriasis y dermatitis atópica; dermatosis crónicas persistentes en placas que no cumplen criterios histológicos de micosis fungoide (pre-LCCT) (n=8) y pacientes sanos (n=4). Se ha estudiado la expresión de los antígenos LFA-1, ICAM-1, ICAM-3, CLA, selectina E, VLA-4, VCAM-1, αE β7 y cadherina E. Los parámetros de inmunotinción valorados no han permitido demostrar diferencias estadísticamente significativas entre los grupos LCCT inicial y avanzado, pero sí con respecto a otras dermatosis. La expresión de CD103 e ICAM-3 por campo epidérmico de 400× puede emplearse como variable para distinguir entre los distintos subgrupos estudiados, salvo en el caso de la comparación entre LCCT y pre-LCCT. Estos dos últimos grupos presentan diferencias estadísticamente significativas en la observación de la expresión de selectina E a 400× y la determinación del patrón en forma de panal de ICAM-1 en los queratinocitos epidérmicos. La expresión de MAC que participan en los fenómenos de adhesión y trasmigración de los linfocitos en la piel no difiere significativamente entre las fases inicial y avanzada de los LCCT. Cell adhesion molecules play a pivotal role in the establishment of T-cell populations in the skin. In this study, we quantify the expression of cell adhesion molecules in patients with cutaneous T-cell lymphoma (CTCL) and compare it with the expression found in other skin diseases. Frozen material was obtained from 42 patients in 5 different groups: early CTCL, comprising patients with patch- and plaque-stage of mycosis fungoides (n=11); advanced CTCL (n=7), comprising patients with mycosis fungoides (n=3) and Sézary syndrome (n=4); inflammatory skin disease (n=12), comprising patients with psoriasis (n=9) and atopic dermatitis (n=3); chronic skin diseases with persistent plaques that do not fulfil the histological criteria for mycosis fungoides (pre-CTCL) (n=8); and healthy volunteers (n=4). Expression of the following cell adhesion molecules was analyzed: lymphocyte function-associated antigen 1, intercellular adhesion molecule 1 (ICAM-1), ICAM-3, cutaneous lymphocyte-associated antigen, E-selectin, very late antigen 4, vascular cell adhesion molecule 1, alphaEbeta7 integrin, and E-cadherin. The immunohistochemical analyses used here revealed statistically significant differences between CTCL and other skin diseases but not between early and advanced CTCL. The expression of alphaEbeta7 integrin and ICAM-3 in the epidermis per high-power field (400× magnification) allowed the different groups to be distinguished from each other, except for advanced CTCL and pre-CTCL. There were statistically significant differences between advanced CTCL and pre-CTCL in terms of the expression of E-selectin at 400× magnification and the expression of ICAM-1 in a honeycomb pattern in epidermal keratinocytes. The expression of cell adhesion molecules involved in the adhesion and migration of lymphocytes in the skin does not differ significantly between initial and advanced stages of CTCL." @default.
• W2015162868 created "2016-06-24" @default.
• W2015162868 creator A5010081624 @default.
• W2015162868 creator A5042490224 @default.
• W2015162868 date "2010-12-01" @default.
• W2015162868 modified "2023-09-27" @default.
• W2015162868 title "Análisis comparativo de la expresión de moléculas de adhesión celular en linfomas cutáneos (micosis fungoide/síndrome de Sézary) y dermatosis inflamatorias mediadas por células T" @default.
• W2015162868 cites W1537188001 @default.
• W2015162868 cites W1900762885 @default.
• W2015162868 cites W1908293564 @default.
• W2015162868 cites W1966397392 @default.
• W2015162868 cites W1970168286 @default.
• W2015162868 cites W1977658676 @default.
• W2015162868 cites W1985631934 @default.
• W2015162868 cites W1999233620 @default.
• W2015162868 cites W2010050195 @default.
• W2015162868 cites W2015828565 @default.
• W2015162868 cites W2039522938 @default.
• W2015162868 cites W2056752410 @default.
• W2015162868 cites W2057309114 @default.
• W2015162868 cites W2057435183 @default.
• W2015162868 cites W2060094282 @default.
• W2015162868 cites W2079748356 @default.
• W2015162868 cites W2085530372 @default.
• W2015162868 cites W2096160655 @default.
• W2015162868 cites W2099675490 @default.
• W2015162868 cites W2100780330 @default.
• W2015162868 cites W2135252042 @default.
• W2015162868 cites W2160053461 @default.
• W2015162868 cites W2324450935 @default.
• W2015162868 cites W2330401583 @default.
• W2015162868 cites W4361865601 @default.
• W2015162868 doi "https://doi.org/10.1016/j.ad.2010.04.007" @default.
• W2015162868 hasPublicationYear "2010" @default.
• W2015162868 type Work @default.
• W2015162868 sameAs 2015162868 @default.
• W2015162868 citedByCount "1" @default.
• W2015162868 countsByYear W20151628682019 @default.
• W2015162868 crossrefType "journal-article" @default.
• W2015162868 hasAuthorship W2015162868A5010081624 @default.
• W2015162868 hasAuthorship W2015162868A5042490224 @default.
• W2015162868 hasConcept C138885662 @default.
• W2015162868 hasConcept C153911025 @default.
• W2015162868 hasConcept C15708023 @default.
• W2015162868 hasConcept C71924100 @default.
• W2015162868 hasConcept C86803240 @default.
• W2015162868 hasConceptScore W2015162868C138885662 @default.
• W2015162868 hasConceptScore W2015162868C153911025 @default.
• W2015162868 hasConceptScore W2015162868C15708023 @default.
• W2015162868 hasConceptScore W2015162868C71924100 @default.
• W2015162868 hasConceptScore W2015162868C86803240 @default.
• W2015162868 hasIssue "10" @default.
• W2015162868 hasLocation W20151628681 @default.
• W2015162868 hasOpenAccess W2015162868 @default.
• W2015162868 hasPrimaryLocation W20151628681 @default.
• W2015162868 hasRelatedWork W1506200166 @default.
• W2015162868 hasRelatedWork W1995515455 @default.
• W2015162868 hasRelatedWork W2048182022 @default.
• W2015162868 hasRelatedWork W2080531066 @default.
• W2015162868 hasRelatedWork W2604872355 @default.
• W2015162868 hasRelatedWork W2748952813 @default.
• W2015162868 hasRelatedWork W2899084033 @default.
• W2015162868 hasRelatedWork W3031052312 @default.
• W2015162868 hasRelatedWork W3032375762 @default.
• W2015162868 hasRelatedWork W3108674512 @default.
• W2015162868 hasVolume "101" @default.
• W2015162868 isParatext "false" @default.
• W2015162868 isRetracted "false" @default.
• W2015162868 magId "2015162868" @default.
• W2015162868 workType "article" @default.