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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015177518> ?p ?o ?g. }

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• W2015177518 abstract "A series of 1,2,4-triazolo[1,5-a]pyrimidin-7(3H)-ones with excellent enzyme inhibition, improved isoform selectivity, and excellent inhibition of downstream phosphorylation of AKT has been identified. Several compounds in the series demonstrated potent (∼ 0.100 μM IC50) growth inhibition in a PTEN deficient cancer cell line." @default.
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• W2015177518 date "2012-05-01" @default.
• W2015177518 modified "2023-09-25" @default.
• W2015177518 title "Synthesis and structure–activity relationships of 1,2,4-triazolo[1,5-a]pyrimidin-7(3H)-ones as novel series of potent β isoform selective phosphatidylinositol 3-kinase inhibitors" @default.
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• W2015177518 doi "https://doi.org/10.1016/j.bmcl.2012.03.039" @default.
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