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• W2015186789 abstract "Future Medicinal ChemistryVol. 5, No. 8 EditorialVitamin K: a structural basis for the design of novel neuroprotective agents?C James Chou, Elizabeth S Inks & Benjamin J JoseyC James Chou* Author for correspondenceDepartment of Drug Discovery & Biomedical Sciences, South Carolina College of Pharmacy, Medical University of South Carolina, Charleston, SC 29425, USA. Search for more papers by this authorEmail the corresponding author at chouc@musc.edu, Elizabeth S InksDepartment of Drug Discovery & Biomedical Sciences, South Carolina College of Pharmacy, Medical University of South Carolina, Charleston, SC 29425, USASearch for more papers by this author & Benjamin J JoseyDepartment of Drug Discovery & Biomedical Sciences, South Carolina College of Pharmacy, Medical University of South Carolina, Charleston, SC 29425, USASearch for more papers by this authorPublished Online:20 May 2013https://doi.org/10.4155/fmc.13.70AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInRedditEmail View articleKeywords: Alzheimer’s diseasemenaquinonemitochondrial diseaseMK-4neuronParkinson’s diseaseUBIAD1vitamin Kvitamin K2References1 Dam H. The antihaemorrhagic vitamin of the chick. Biochem. J.29(6),1273–1285 (1935).Crossref, Medline, CAS, Google Scholar2 Shearer MJ. Vitamin K. Lancet345(8944),229–234 (1995).Crossref, Medline, CAS, Google Scholar3 Shearer MJ, Newman P. Metabolism and cell biology of vitamin K. Thromb. Haemost.100(4),530–547 (2008).Crossref, Medline, CAS, Google Scholar4 Ferland G. Vitamin K and the nervous system: an overview of its actions. Adv. Nutr.3(2),204–212 (2012).Crossref, Medline, CAS, Google Scholar5 Thijssen HH, Vervoort LM, Schurgers LJ, Shearer MJ. Menadione is a metabolite of oral vitamin K. Br. J. Nutr.95(2),260–266 (2006).Crossref, Medline, CAS, Google Scholar6 Nakagawa K, Hirota Y, Sawada N et al. Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme. Nature468(7320),117–121 (2010).Crossref, Medline, CAS, Google Scholar7 Allison AC. The possible role of vitamin K deficiency in the pathogenesis of Alzheimer’s disease and in augmenting brain damage associated with cardiovascular disease. Med. Hypotheses57(2),151–155 (2001).Crossref, Medline, CAS, Google Scholar8 Lindahl B, Eriksson L, Spillmann D, Caterson B, Lindahl U. Selective loss of cerebral keratan sulfate in Alzheimer’s disease. J. Biol. Chem.271(29),16991–16994 (1996).Crossref, Medline, CAS, Google Scholar9 Presse N, Shatenstein B, Kergoat MJ, Ferland G. Low vitamin K intakes in community-dwelling elders at an early stage of Alzheimer’s disease. J. Am. Diet. Assoc.108(12),2095–2099 (2008).Crossref, Medline, Google Scholar10 Huber AM, Davidson KW, O’Brien-Morse ME, Sadowski JA. Gender differences in hepatic phylloquinone and menaquinones in the vitamin K-deficient and -supplemented rat. Biochim. Biophys. Acta1426(1),43–52 (1999).Crossref, Medline, CAS, Google Scholar11 Kohlmeier M, Salomon A, Saupe J, Shearer MJ. Transport of vitamin K to bone in humans. J. Nutr.126(4 Suppl.),1192S–1196S (1996).Crossref, Medline, CAS, Google Scholar12 Mayeux R, Saunders AM, Shea S et al. Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer’s disease. Alzheimer’s Disease Centers Consortium on Apolipoprotein E and Alzheimer’s Disease. N. Engl. J. Med.338(8),506–511 (1998).Crossref, Medline, CAS, Google Scholar13 Vos M, Esposito G, Edirisinghe JN et al. Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency. Science336(6086),1306–1310 (2012).Crossref, Medline, CAS, Google Scholar14 Josey BJ, Inks ES, Wen X, Chou CJ. Structure–activity relationship study of vitamin k derivatives yields highly potent neuroprotective agents. J. Med. Chem.56(3),1007–1022 (2013).Crossref, Medline, CAS, Google Scholar15 Erb M, Hoffmann-Enger B, Deppe H et al. Features of idebenone and related short-chain quinones that rescue ATP levels under conditions of impaired mitochondrial complex I. PLoS ONE7(4),e36153 (2012).Crossref, Medline, CAS, Google Scholar16 Enns GM, Kinsman SL, Perlman SL et al. Initial experience in the treatment of inherited mitochondrial disease with EPI-743. Mol. Genet. Metab.105(1),91–102 (2012).Crossref, Medline, CAS, Google Scholar17 Lynch DR, Willi SM, Wilson RB et al. A0001 in Friedreich ataxia: biochemical characterization and effects in a clinical trial. Mov. Disord.27(8),1026–1033 (2012).Crossref, Medline, CAS, Google Scholar18 Meier T, Perlman SL, Rummey C, Coppard NJ, Lynch DR. Assessment of neurological efficacy of idebenone in pediatric patients with Friedreich’s ataxia: data from a 6-month controlled study followed by a 12-month open-label extension study. J. Neurol.259(2),284–291 (2012).Crossref, Medline, CAS, Google Scholar19 Martinelli D, Catteruccia M, Piemonte F et al. EPI-743 reverses the progression of the pediatric mitochondrial disease – genetically defined Leigh Syndrome. Mol. Genet. Metab.107(3),383–388 (2012).Crossref, Medline, CAS, Google Scholar20 Sato T, Schurgers LJ, Uenishi K. Comparison of menaquinone-4 and menaquinone-7 bioavailability in healthy women. Nutr. J.11,93 (2012).Crossref, Medline, CAS, Google ScholarFiguresReferencesRelatedDetailsCited ByA novel vitamin K derived anticoagulant tolerant to genetic variations of vitamin K epoxide reductaseJournal of Thrombosis and Haemostasis, Vol. 19, No. 3Turning Donepezil into a Multi‐Target‐Directed Ligand through a Merging Strategy31 August 2020 | ChemMedChem, Vol. 16, No. 1Medicinal Chemistry of Hybrids for Neurodegenerative DiseasesMultitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects10 October 2014 | Journal of Medicinal Chemistry, Vol. 57, No. 20 Vol. 5, No. 8 STAY CONNECTED Metrics Downloaded 96 times History Published online 20 May 2013 Published in print May 2013 Information© Future Science LtdKeywordsAlzheimer’s diseasemenaquinonemitochondrial diseaseMK-4neuronParkinson’s diseaseUBIAD1vitamin Kvitamin K2Financial & competing interest disclosureCJ Chou is supported by NIH grants from the National Cancer Institute 1R01CA163452, and grants from the National Center for Research Resources, 5P20RR024485-02, and the National Institute of General Medical Sciences, 8P20GM103542-02. BJ Josey is supported by NIH/NHLBI pre-doctoral training fellowship, T32-HL007260-36. The authors have a provisional patent application in process for vitamin K analogs. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.No writing assistance was utilized in the production of this manuscript.PDF download" @default.
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