FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015199304> ?p ?o ?g. }

• W2015199304 endingPage "302" @default.
• W2015199304 startingPage "293" @default.
• W2015199304 abstract "Heat shock protein 70 (HSP70) protect cell from oxidative stress by preventing the irreversible loss of vital proteins and facilitating their subsequent regeneration. Silver carp (Hypophthalmichthys molitrix), grass carp (Ctenopharyngodon idellus), and Nile tilapia (Oreochromis nilotica) are three warm freshwater fishes with differential tolerance to microcystin-LR (MC-LR). Full-length cDNAs encoding the HSP70 were cloned from the livers of the three fishes. The HSP70 cDNAs of silver carp, grass carp, and Nile tilapia were 2356, 2348, and 2242 bp in length and contained an open-reading frame of 1950 bp (encoding a polypeptide of 649 amino acids), 1950 bp (649 amino acids), and 1917 bp (638 amino acids), respectively. Like mammalian HSP70, the HSP70 of the three fish was also composed of an ATPase domain from residues 1 to 383 (44 kDa), substrate peptide binding domain from residues 384 to 544 (18 kDa), and a C-terminus domain from residues 545 to 649 (10 kDa). The relatively high conservation of HSP70 sequences among different vertebrates is consistent with their important role in fundamental cellular processes. Using beta-actin as an external control, RT-PCR within the exponential phase was conducted to determine the constitutive and inducible expression level of HSP70 gene among the three fishes (6-12 g) intraperitoneally injected with MC-LR (50 μg kg(-1) body weight). Both constitutive and inducible liver mRNA levels of the fish HSP70 genes showed positive relationships with their tolerance to MC-LR: highest in Nile tilapia, followed by silver carp, and lowest in grass carp. The differential expression pattern of liver HSP70 genes in the three fish indicated a potential role of HSP70 in the detoxification process of MC-LR." @default.
• W2015199304 created "2016-06-24" @default.
• W2015199304 creator A5004808253 @default.
• W2015199304 creator A5038225936 @default.
• W2015199304 creator A5040911309 @default.
• W2015199304 creator A5047773028 @default.
• W2015199304 creator A5053275663 @default.
• W2015199304 creator A5070112759 @default.
• W2015199304 date "2010-09-01" @default.
• W2015199304 modified "2023-10-06" @default.
• W2015199304 title "Molecular characterization of heat shock protein 70 genes in the liver of three warm freshwater fishes with differential tolerance to microcystin-LR" @default.
• W2015199304 cites W1965718556 @default.
• W2015199304 cites W1966031969 @default.
• W2015199304 cites W1967138582 @default.
• W2015199304 cites W1971218766 @default.
• W2015199304 cites W1976001505 @default.
• W2015199304 cites W1985355582 @default.
• W2015199304 cites W1992022999 @default.
• W2015199304 cites W1996218569 @default.
• W2015199304 cites W2002426641 @default.
• W2015199304 cites W2005019579 @default.
• W2015199304 cites W2007951643 @default.
• W2015199304 cites W2008257836 @default.
• W2015199304 cites W2009761822 @default.
• W2015199304 cites W2019362179 @default.
• W2015199304 cites W2024413216 @default.
• W2015199304 cites W2030524684 @default.
• W2015199304 cites W2032252966 @default.
• W2015199304 cites W2036173820 @default.
• W2015199304 cites W2040766609 @default.
• W2015199304 cites W2043685930 @default.
• W2015199304 cites W2048449150 @default.
• W2015199304 cites W2056074767 @default.
• W2015199304 cites W2057878460 @default.
• W2015199304 cites W2058689219 @default.
• W2015199304 cites W2061402711 @default.
• W2015199304 cites W2062844242 @default.
• W2015199304 cites W2077012992 @default.
• W2015199304 cites W2082206379 @default.
• W2015199304 cites W2095080787 @default.
• W2015199304 cites W2101194847 @default.
• W2015199304 cites W2103965206 @default.
• W2015199304 cites W2120073702 @default.
• W2015199304 cites W2120982766 @default.
• W2015199304 cites W2145492803 @default.
• W2015199304 cites W2147464247 @default.
• W2015199304 cites W2156801294 @default.
• W2015199304 cites W2171191338 @default.
• W2015199304 cites W401970286 @default.
• W2015199304 cites W4247920653 @default.
• W2015199304 cites W43991757 @default.
• W2015199304 doi "https://doi.org/10.1002/jbt.20338" @default.
• W2015199304 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20979155" @default.
• W2015199304 hasPublicationYear "2010" @default.
• W2015199304 type Work @default.
• W2015199304 sameAs 2015199304 @default.
• W2015199304 citedByCount "17" @default.
• W2015199304 countsByYear W20151993042012 @default.
• W2015199304 countsByYear W20151993042013 @default.
• W2015199304 countsByYear W20151993042014 @default.
• W2015199304 countsByYear W20151993042017 @default.
• W2015199304 countsByYear W20151993042018 @default.
• W2015199304 countsByYear W20151993042019 @default.
• W2015199304 countsByYear W20151993042020 @default.
• W2015199304 countsByYear W20151993042022 @default.
• W2015199304 countsByYear W20151993042023 @default.
• W2015199304 crossrefType "journal-article" @default.
• W2015199304 hasAuthorship W2015199304A5004808253 @default.
• W2015199304 hasAuthorship W2015199304A5038225936 @default.
• W2015199304 hasAuthorship W2015199304A5040911309 @default.
• W2015199304 hasAuthorship W2015199304A5047773028 @default.
• W2015199304 hasAuthorship W2015199304A5053275663 @default.
• W2015199304 hasAuthorship W2015199304A5070112759 @default.
• W2015199304 hasConcept C104317684 @default.
• W2015199304 hasConcept C153911025 @default.
• W2015199304 hasConcept C167625842 @default.
• W2015199304 hasConcept C205260736 @default.
• W2015199304 hasConcept C2776654248 @default.
• W2015199304 hasConcept C2777407658 @default.
• W2015199304 hasConcept C2778658382 @default.
• W2015199304 hasConcept C2779286987 @default.
• W2015199304 hasConcept C2779668946 @default.
• W2015199304 hasConcept C2780129523 @default.
• W2015199304 hasConcept C2781257293 @default.
• W2015199304 hasConcept C2909208804 @default.
• W2015199304 hasConcept C47289529 @default.
• W2015199304 hasConcept C505870484 @default.
• W2015199304 hasConcept C515207424 @default.
• W2015199304 hasConcept C55493867 @default.
• W2015199304 hasConcept C68991219 @default.
• W2015199304 hasConcept C86803240 @default.
• W2015199304 hasConceptScore W2015199304C104317684 @default.
• W2015199304 hasConceptScore W2015199304C153911025 @default.
• W2015199304 hasConceptScore W2015199304C167625842 @default.
• W2015199304 hasConceptScore W2015199304C205260736 @default.
• W2015199304 hasConceptScore W2015199304C2776654248 @default.
• W2015199304 hasConceptScore W2015199304C2777407658 @default.
• W2015199304 hasConceptScore W2015199304C2778658382 @default.

• next