Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015229056> ?p ?o ?g. }
- W2015229056 endingPage "280" @default.
- W2015229056 startingPage "276" @default.
- W2015229056 abstract "Concentrations of the neuroactive steroid 3α,5α-tetrahydroprogesterone (TH PROG or allopregnanolone) and its precursors progesterone (PROG) and 5α-dihydroprogesterone (DH PROG) have been measured in mouse brain throughout the oestrous cycle. Plasma PROG concentrations were also measured for comparison. At each stage, circadian fluctuations were found in the concentrations of brain PROG and its metabolites. Such fluctuations were greater than those attributable to any particular stage of the oestrous cycle. Over the entire cycle, a significant correlation was found between brain TH PROG (or DH PROG) and PROG concentrations but not between brain TH PROG (or DH PROG) and plasma PROG concentrations. There was also no correlation between endogenous TH PROG (or DH PROG) and activity of the 5α-reductase converting 3H-PROG to 3H-DH PROG in whole brain homogenates. Concentrations of another neuroactive steroid, pregnenolone sulphate (PREG S), in the brain during the oestrous cycle were in phase with plasma PROG but not brain PROG concentrations. Our results indicate that circadian and ovarian influences on the concentrations of PROG and its metabolite TH PROG in female whole mouse brain are caused predominantly by changes in the supply of PROG from within the tissue, whatever the contribution of peripheral sources." @default.
- W2015229056 created "2016-06-24" @default.
- W2015229056 creator A5050647212 @default.
- W2015229056 creator A5057846157 @default.
- W2015229056 creator A5080980963 @default.
- W2015229056 creator A5086264826 @default.
- W2015229056 creator A5088943384 @default.
- W2015229056 creator A5091440155 @default.
- W2015229056 date "1997-08-01" @default.
- W2015229056 modified "2023-10-02" @default.
- W2015229056 title "Brain neurosteroids during the mouse oestrous cycle" @default.
- W2015229056 cites W1516108907 @default.
- W2015229056 cites W1971270636 @default.
- W2015229056 cites W1983757175 @default.
- W2015229056 cites W1987263856 @default.
- W2015229056 cites W1988218442 @default.
- W2015229056 cites W1989973227 @default.
- W2015229056 cites W1991574617 @default.
- W2015229056 cites W1992357100 @default.
- W2015229056 cites W2003059145 @default.
- W2015229056 cites W2006442321 @default.
- W2015229056 cites W2008392190 @default.
- W2015229056 cites W2008871773 @default.
- W2015229056 cites W2010052375 @default.
- W2015229056 cites W2016224977 @default.
- W2015229056 cites W2016858531 @default.
- W2015229056 cites W2035512979 @default.
- W2015229056 cites W2048450600 @default.
- W2015229056 cites W2056932896 @default.
- W2015229056 cites W2064833080 @default.
- W2015229056 cites W2065556700 @default.
- W2015229056 cites W2068134217 @default.
- W2015229056 cites W2078486435 @default.
- W2015229056 cites W2079103153 @default.
- W2015229056 cites W2085824832 @default.
- W2015229056 cites W2093601807 @default.
- W2015229056 cites W2146853018 @default.
- W2015229056 cites W2321650879 @default.
- W2015229056 cites W2322547577 @default.
- W2015229056 cites W2416199546 @default.
- W2015229056 cites W4238573373 @default.
- W2015229056 cites W4245117662 @default.
- W2015229056 cites W4293247451 @default.
- W2015229056 doi "https://doi.org/10.1016/s0006-8993(97)00749-x" @default.
- W2015229056 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9359616" @default.
- W2015229056 hasPublicationYear "1997" @default.
- W2015229056 type Work @default.
- W2015229056 sameAs 2015229056 @default.
- W2015229056 citedByCount "108" @default.
- W2015229056 countsByYear W20152290562012 @default.
- W2015229056 countsByYear W20152290562013 @default.
- W2015229056 countsByYear W20152290562014 @default.
- W2015229056 countsByYear W20152290562015 @default.
- W2015229056 countsByYear W20152290562016 @default.
- W2015229056 countsByYear W20152290562017 @default.
- W2015229056 countsByYear W20152290562018 @default.
- W2015229056 countsByYear W20152290562019 @default.
- W2015229056 countsByYear W20152290562020 @default.
- W2015229056 countsByYear W20152290562021 @default.
- W2015229056 countsByYear W20152290562022 @default.
- W2015229056 countsByYear W20152290562023 @default.
- W2015229056 crossrefType "journal-article" @default.
- W2015229056 hasAuthorship W2015229056A5050647212 @default.
- W2015229056 hasAuthorship W2015229056A5057846157 @default.
- W2015229056 hasAuthorship W2015229056A5080980963 @default.
- W2015229056 hasAuthorship W2015229056A5086264826 @default.
- W2015229056 hasAuthorship W2015229056A5088943384 @default.
- W2015229056 hasAuthorship W2015229056A5091440155 @default.
- W2015229056 hasConcept C121446783 @default.
- W2015229056 hasConcept C126322002 @default.
- W2015229056 hasConcept C134018914 @default.
- W2015229056 hasConcept C16613235 @default.
- W2015229056 hasConcept C168258287 @default.
- W2015229056 hasConcept C170493617 @default.
- W2015229056 hasConcept C185592680 @default.
- W2015229056 hasConcept C1998276 @default.
- W2015229056 hasConcept C2776801781 @default.
- W2015229056 hasConcept C2777477808 @default.
- W2015229056 hasConcept C2778338918 @default.
- W2015229056 hasConcept C2780193516 @default.
- W2015229056 hasConcept C2780902042 @default.
- W2015229056 hasConcept C2780957381 @default.
- W2015229056 hasConcept C44796713 @default.
- W2015229056 hasConcept C71315377 @default.
- W2015229056 hasConcept C71924100 @default.
- W2015229056 hasConcept C86803240 @default.
- W2015229056 hasConceptScore W2015229056C121446783 @default.
- W2015229056 hasConceptScore W2015229056C126322002 @default.
- W2015229056 hasConceptScore W2015229056C134018914 @default.
- W2015229056 hasConceptScore W2015229056C16613235 @default.
- W2015229056 hasConceptScore W2015229056C168258287 @default.
- W2015229056 hasConceptScore W2015229056C170493617 @default.
- W2015229056 hasConceptScore W2015229056C185592680 @default.
- W2015229056 hasConceptScore W2015229056C1998276 @default.
- W2015229056 hasConceptScore W2015229056C2776801781 @default.
- W2015229056 hasConceptScore W2015229056C2777477808 @default.
- W2015229056 hasConceptScore W2015229056C2778338918 @default.
- W2015229056 hasConceptScore W2015229056C2780193516 @default.