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- W2015230022 endingPage "514" @default.
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- W2015230022 abstract "During HIV infection, the timing of opportunistic infections is not always associated with severity of CD4 T cell depletion, and different opportunistic pathogens reactivate at different CD4 T cell thresholds. Here, we examine how differences in the phenotype and function of pathogen-specific CD4 T cells influence susceptibility to HIV infection. By focusing on three common opportunistic infections (Mycobacterium tuberculosis, human papillomavirus, and cytomegalovirus), we investigate how differential depletion of pathogen-specific CD4 T cells impacts the natural history of these pathogens in HIV infection. A broader understanding of this relationship can better inform treatment strategies against copathogens. During HIV infection, the timing of opportunistic infections is not always associated with severity of CD4 T cell depletion, and different opportunistic pathogens reactivate at different CD4 T cell thresholds. Here, we examine how differences in the phenotype and function of pathogen-specific CD4 T cells influence susceptibility to HIV infection. By focusing on three common opportunistic infections (Mycobacterium tuberculosis, human papillomavirus, and cytomegalovirus), we investigate how differential depletion of pathogen-specific CD4 T cells impacts the natural history of these pathogens in HIV infection. A broader understanding of this relationship can better inform treatment strategies against copathogens." @default.
- W2015230022 created "2016-06-24" @default.
- W2015230022 creator A5004218416 @default.
- W2015230022 creator A5020230187 @default.
- W2015230022 date "2013-10-01" @default.
- W2015230022 modified "2023-10-10" @default.
- W2015230022 title "T Cell Susceptibility to HIV Influences Outcome of Opportunistic Infections" @default.
- W2015230022 cites W1483831487 @default.
- W2015230022 cites W156003141 @default.
- W2015230022 cites W1698869900 @default.
- W2015230022 cites W1868950919 @default.
- W2015230022 cites W1914813822 @default.
- W2015230022 cites W1967267361 @default.
- W2015230022 cites W1972874505 @default.
- W2015230022 cites W1972960900 @default.
- W2015230022 cites W1978632090 @default.
- W2015230022 cites W1978954636 @default.
- W2015230022 cites W1984999783 @default.
- W2015230022 cites W1991295106 @default.
- W2015230022 cites W1991464170 @default.
- W2015230022 cites W1994938942 @default.
- W2015230022 cites W1995273554 @default.
- W2015230022 cites W1996573297 @default.
- W2015230022 cites W1996770717 @default.
- W2015230022 cites W2004937435 @default.
- W2015230022 cites W2006152917 @default.
- W2015230022 cites W2008732636 @default.
- W2015230022 cites W2008994596 @default.
- W2015230022 cites W2009607549 @default.
- W2015230022 cites W2014985358 @default.
- W2015230022 cites W2016488838 @default.
- W2015230022 cites W2020573981 @default.
- W2015230022 cites W2021154253 @default.
- W2015230022 cites W2021388574 @default.
- W2015230022 cites W2025214951 @default.
- W2015230022 cites W2027225184 @default.
- W2015230022 cites W2027392559 @default.
- W2015230022 cites W2028462978 @default.
- W2015230022 cites W2028583836 @default.
- W2015230022 cites W2035054077 @default.
- W2015230022 cites W2036234686 @default.
- W2015230022 cites W2038621149 @default.
- W2015230022 cites W2040780498 @default.
- W2015230022 cites W2043223046 @default.
- W2015230022 cites W2044410754 @default.
- W2015230022 cites W2046552182 @default.
- W2015230022 cites W2048019396 @default.
- W2015230022 cites W2052248659 @default.
- W2015230022 cites W2053901884 @default.
- W2015230022 cites W2054784359 @default.
- W2015230022 cites W2054957138 @default.
- W2015230022 cites W2063205690 @default.
- W2015230022 cites W2072680575 @default.
- W2015230022 cites W2073847287 @default.
- W2015230022 cites W2074673603 @default.
- W2015230022 cites W2076649068 @default.
- W2015230022 cites W2083796093 @default.
- W2015230022 cites W2089226849 @default.
- W2015230022 cites W2089532656 @default.
- W2015230022 cites W2091772630 @default.
- W2015230022 cites W2095820984 @default.
- W2015230022 cites W2097553376 @default.
- W2015230022 cites W2102354280 @default.
- W2015230022 cites W2103849595 @default.
- W2015230022 cites W2107876252 @default.
- W2015230022 cites W2108811173 @default.
- W2015230022 cites W2109263605 @default.
- W2015230022 cites W2111954892 @default.
- W2015230022 cites W2112362733 @default.
- W2015230022 cites W2114328141 @default.
- W2015230022 cites W2115180633 @default.
- W2015230022 cites W2115377212 @default.
- W2015230022 cites W2116687125 @default.
- W2015230022 cites W2121327992 @default.
- W2015230022 cites W2123185544 @default.
- W2015230022 cites W2123717316 @default.
- W2015230022 cites W2124580054 @default.
- W2015230022 cites W2125424508 @default.
- W2015230022 cites W2126368931 @default.
- W2015230022 cites W2128827386 @default.
- W2015230022 cites W2128892251 @default.
- W2015230022 cites W2129057663 @default.
- W2015230022 cites W2130046741 @default.
- W2015230022 cites W2130981365 @default.
- W2015230022 cites W2131550376 @default.
- W2015230022 cites W2132007861 @default.
- W2015230022 cites W2136121931 @default.
- W2015230022 cites W2137611357 @default.
- W2015230022 cites W2139577725 @default.
- W2015230022 cites W2144037573 @default.
- W2015230022 cites W2144445894 @default.
- W2015230022 cites W2148507351 @default.
- W2015230022 cites W2148643959 @default.
- W2015230022 cites W2149336529 @default.
- W2015230022 cites W2150047352 @default.
- W2015230022 cites W2150645172 @default.
- W2015230022 cites W2152906249 @default.
- W2015230022 cites W2153612828 @default.