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- W2015239425 abstract "Quinacrine and a photoactivatable congener, quinacrine azide, were applied to the intracellular membrane surface of voltage-clamped squid giant axons using internal perfusion techniques. Both compounds were found to reversibly block voltage-dependent sodium channels under dark conditions. Potassium channels were blocked to a lesser extent. Upon irradiation an irreversible block of sodium channels developed with quinacrine azide, but not with quinacrine. Quinacrine azide may thus represent a class of useful photoaffinity probes of voltage-dependent ionic channels." @default.
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- W2015239425 date "1982-02-01" @default.
- W2015239425 modified "2023-10-18" @default.
- W2015239425 title "Azidoacridines as photoaffinity probes for ionic channels in excitable membranes" @default.
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- W2015239425 doi "https://doi.org/10.1016/0006-291x(82)91432-2" @default.
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