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- W2015247320 abstract "Novel estrogen-conjugated pyridine-containing Gd(III) and Eu(III) contrast agents (EPTA-Gd/Eu) were designed and effectively synthesized. Convenient to administration and MRI experiments, both EPTA-Gd and EPTA-Eu are soluble in water. The EPTA-Gd selectively binds with a micromolar affinity to the estrogen receptor and induces proliferation of human breast cancer cells. The EPTA-Gd is not lethal and does not cause any adverse effects when administrated intravenously. It enhances T1 and T2 nuclear relaxation rates of water and serves as a selective contrast agent for localizing the estrogen receptor by MRI." @default.
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- W2015247320 date "2007-09-01" @default.
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- W2015247320 title "Water-Soluble Contrast Agents Targeted at the Estrogen Receptor for Molecular Magnetic Resonance Imaging" @default.
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- W2015247320 doi "https://doi.org/10.1021/bc700230m" @default.
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