FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015260445> ?p ?o ?g. }

• W2015260445 endingPage "107" @default.
• W2015260445 startingPage "100" @default.
• W2015260445 abstract "Oxalate oxidase (E.C. 1.2.3.4) catalyzes the oxygen-dependent oxidation of oxalate to carbon dioxide in a reaction that is coupled with the formation of hydrogen peroxide. Although there is currently no structural information available for oxalate oxidase from Ceriporiopsis subvermispora (CsOxOx), sequence data and homology modeling indicate that it is the first manganese-containing bicupin enzyme identified that catalyzes this reaction. Interestingly, CsOxOx shares greatest sequence homology with bicupin microbial oxalate decarboxylases (OxDC). We show that CsOxOx activity directly correlates with Mn content and other metals do not appear to be able to support catalysis. EPR spectra indicate that the Mn is present as Mn(II), and are consistent with the coordination environment expected from homology modeling with known X-ray crystal structures of OxDC from Bacillus subtilis. EPR spin-trapping experiments support the existence of an oxalate-derived radical species formed during turnover. Acetate and a number of other small molecule carboxylic acids are competitive inhibitors for oxalate in the CsOxOx catalyzed reaction. The pH dependence of this reaction suggests that the dominant contribution to catalysis comes from the monoprotonated form of oxalate binding to a form of the enzyme in which an active site carboxylic acid residue must be unprotonated." @default.
• W2015260445 created "2016-06-24" @default.
• W2015260445 creator A5009547638 @default.
• W2015260445 creator A5021746199 @default.
• W2015260445 creator A5023766873 @default.
• W2015260445 creator A5025793804 @default.
• W2015260445 creator A5033047262 @default.
• W2015260445 creator A5034397418 @default.
• W2015260445 creator A5035732605 @default.
• W2015260445 creator A5047278127 @default.
• W2015260445 creator A5069838082 @default.
• W2015260445 creator A5071372754 @default.
• W2015260445 date "2011-05-01" @default.
• W2015260445 modified "2023-10-11" @default.
• W2015260445 title "Characterization of Ceriporiopsis subvermispora bicupin oxalate oxidase expressed in Pichia pastoris" @default.
• W2015260445 cites W1493441455 @default.
• W2015260445 cites W1604636323 @default.
• W2015260445 cites W1753190741 @default.
• W2015260445 cites W1775749144 @default.
• W2015260445 cites W1834232289 @default.
• W2015260445 cites W1963835649 @default.
• W2015260445 cites W1965900569 @default.
• W2015260445 cites W1966535612 @default.
• W2015260445 cites W1967420429 @default.
• W2015260445 cites W1967964640 @default.
• W2015260445 cites W1973840240 @default.
• W2015260445 cites W1994125097 @default.
• W2015260445 cites W2005695292 @default.
• W2015260445 cites W2006033629 @default.
• W2015260445 cites W2023351589 @default.
• W2015260445 cites W2026817497 @default.
• W2015260445 cites W2027707636 @default.
• W2015260445 cites W2031532912 @default.
• W2015260445 cites W2041230751 @default.
• W2015260445 cites W2048603584 @default.
• W2015260445 cites W2056091365 @default.
• W2015260445 cites W2056427207 @default.
• W2015260445 cites W2056976711 @default.
• W2015260445 cites W2062996884 @default.
• W2015260445 cites W2065330088 @default.
• W2015260445 cites W2069958671 @default.
• W2015260445 cites W2074233537 @default.
• W2015260445 cites W2077648822 @default.
• W2015260445 cites W2088051811 @default.
• W2015260445 cites W2105592754 @default.
• W2015260445 cites W2108685032 @default.
• W2015260445 cites W2161384465 @default.
• W2015260445 cites W2224356048 @default.
• W2015260445 cites W4247437312 @default.
• W2015260445 cites W4256596702 @default.
• W2015260445 doi "https://doi.org/10.1016/j.abb.2011.02.022" @default.
• W2015260445 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3078958" @default.
• W2015260445 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21376010" @default.
• W2015260445 hasPublicationYear "2011" @default.
• W2015260445 type Work @default.
• W2015260445 sameAs 2015260445 @default.
• W2015260445 citedByCount "25" @default.
• W2015260445 countsByYear W20152604452013 @default.
• W2015260445 countsByYear W20152604452014 @default.
• W2015260445 countsByYear W20152604452015 @default.
• W2015260445 countsByYear W20152604452016 @default.
• W2015260445 countsByYear W20152604452017 @default.
• W2015260445 countsByYear W20152604452019 @default.
• W2015260445 countsByYear W20152604452020 @default.
• W2015260445 countsByYear W20152604452021 @default.
• W2015260445 countsByYear W20152604452022 @default.
• W2015260445 countsByYear W20152604452023 @default.
• W2015260445 crossrefType "journal-article" @default.
• W2015260445 hasAuthorship W2015260445A5009547638 @default.
• W2015260445 hasAuthorship W2015260445A5021746199 @default.
• W2015260445 hasAuthorship W2015260445A5023766873 @default.
• W2015260445 hasAuthorship W2015260445A5025793804 @default.
• W2015260445 hasAuthorship W2015260445A5033047262 @default.
• W2015260445 hasAuthorship W2015260445A5034397418 @default.
• W2015260445 hasAuthorship W2015260445A5035732605 @default.
• W2015260445 hasAuthorship W2015260445A5047278127 @default.
• W2015260445 hasAuthorship W2015260445A5069838082 @default.
• W2015260445 hasAuthorship W2015260445A5071372754 @default.
• W2015260445 hasBestOaLocation W20152604452 @default.
• W2015260445 hasConcept C104317684 @default.
• W2015260445 hasConcept C161790260 @default.
• W2015260445 hasConcept C179104552 @default.
• W2015260445 hasConcept C181199279 @default.
• W2015260445 hasConcept C185592680 @default.
• W2015260445 hasConcept C2776351790 @default.
• W2015260445 hasConcept C2781372317 @default.
• W2015260445 hasConcept C38485361 @default.
• W2015260445 hasConcept C40767141 @default.
• W2015260445 hasConcept C533411734 @default.
• W2015260445 hasConcept C55493867 @default.
• W2015260445 hasConcept C71240020 @default.
• W2015260445 hasConceptScore W2015260445C104317684 @default.
• W2015260445 hasConceptScore W2015260445C161790260 @default.
• W2015260445 hasConceptScore W2015260445C179104552 @default.
• W2015260445 hasConceptScore W2015260445C181199279 @default.
• W2015260445 hasConceptScore W2015260445C185592680 @default.
• W2015260445 hasConceptScore W2015260445C2776351790 @default.
• W2015260445 hasConceptScore W2015260445C2781372317 @default.

• next