FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015266979> ?p ?o ?g. }

• W2015266979 endingPage "1353" @default.
• W2015266979 startingPage "1349" @default.
• W2015266979 abstract "For the diagnosis of acute myocardial infarction (AMI) in patients circulating constituents of the contractile apparatus may be measured instead of cytosolic cardiac enzymes. The potential advantages of the use of myofibrillar cardiac proteins as marker proteins for AMI results from their expression as cardio-specific isoforms, their high intracellular concentration, and their continuous release from infarcting myocardium. While analyzing the specificity of polyclonal goat anti-human cardiac myosin light chains antisera a cardio-specific antibody fraction was identified which is directed against cardiac troponin T contaminations of the myosin light chains antigen. Using this antibody fraction a standardized enzyme immuno-assay for circulating troponin T was developed to detect AMI in patients. In this assay troponin T is bound on different epitopes by affinity purified goat anti-cardiac troponin T antibodies immobilized on polyvinyl chloride test tubes as well as horse raddish peroxidase labeled monoclonal anti-troponin T antibody in liquid phase. The assay procedure can be completed semiautomatically in 90 min with a detection limit of the assay of 0.5 ng/ml human or bovine cardiac troponin T. There is 1% crossreactivity with skeletal troponin T. In 26 healthy volunteers no cardiac troponin T was detectable in serum of 25 persons, while in 1 further volunteer 1 ng/ml troponin T was found. In the sera of all 50 patients with transmural AMI troponin T was elevated ranging from 7.2 to 110 ng/ml. In the mean troponin T remained elevated from three until 300 hours after onset of ischemic pain showing a biphasic serum concentration curve.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W2015266979 created "2016-06-24" @default.
• W2015266979 creator A5039050392 @default.
• W2015266979 creator A5049262839 @default.
• W2015266979 creator A5051005374 @default.
• W2015266979 creator A5051198858 @default.
• W2015266979 creator A5063261137 @default.
• W2015266979 creator A5084026045 @default.
• W2015266979 date "1989-12-01" @default.
• W2015266979 modified "2023-10-14" @default.
• W2015266979 title "Enzyme linked immuno assay of cardiac troponin T for the detection of acute myocardial infarction in patients" @default.
• W2015266979 cites W1556587164 @default.
• W2015266979 cites W1845228072 @default.
• W2015266979 cites W1971715215 @default.
• W2015266979 cites W1976491816 @default.
• W2015266979 cites W2015238427 @default.
• W2015266979 cites W2034887586 @default.
• W2015266979 cites W2051146620 @default.
• W2015266979 cites W2059086329 @default.
• W2015266979 cites W2074105117 @default.
• W2015266979 cites W2087803718 @default.
• W2015266979 cites W2089276240 @default.
• W2015266979 cites W2100837269 @default.
• W2015266979 cites W2133597936 @default.
• W2015266979 cites W2153991279 @default.
• W2015266979 cites W2155045365 @default.
• W2015266979 cites W2155803619 @default.
• W2015266979 cites W2164912846 @default.
• W2015266979 cites W2211408270 @default.
• W2015266979 cites W2396496303 @default.
• W2015266979 cites W2419217870 @default.
• W2015266979 doi "https://doi.org/10.1016/0022-2828(89)90680-9" @default.
• W2015266979 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2632816" @default.
• W2015266979 hasPublicationYear "1989" @default.
• W2015266979 type Work @default.
• W2015266979 sameAs 2015266979 @default.
• W2015266979 citedByCount "419" @default.
• W2015266979 countsByYear W20152669792012 @default.
• W2015266979 countsByYear W20152669792013 @default.
• W2015266979 countsByYear W20152669792014 @default.
• W2015266979 countsByYear W20152669792015 @default.
• W2015266979 countsByYear W20152669792016 @default.
• W2015266979 countsByYear W20152669792017 @default.
• W2015266979 countsByYear W20152669792018 @default.
• W2015266979 countsByYear W20152669792019 @default.
• W2015266979 countsByYear W20152669792020 @default.
• W2015266979 countsByYear W20152669792021 @default.
• W2015266979 countsByYear W20152669792022 @default.
• W2015266979 countsByYear W20152669792023 @default.
• W2015266979 crossrefType "journal-article" @default.
• W2015266979 hasAuthorship W2015266979A5039050392 @default.
• W2015266979 hasAuthorship W2015266979A5049262839 @default.
• W2015266979 hasAuthorship W2015266979A5051005374 @default.
• W2015266979 hasAuthorship W2015266979A5051198858 @default.
• W2015266979 hasAuthorship W2015266979A5063261137 @default.
• W2015266979 hasAuthorship W2015266979A5084026045 @default.
• W2015266979 hasConcept C126322002 @default.
• W2015266979 hasConcept C133927893 @default.
• W2015266979 hasConcept C144469398 @default.
• W2015266979 hasConcept C147483822 @default.
• W2015266979 hasConcept C153911025 @default.
• W2015266979 hasConcept C159654299 @default.
• W2015266979 hasConcept C164705383 @default.
• W2015266979 hasConcept C185592680 @default.
• W2015266979 hasConcept C203014093 @default.
• W2015266979 hasConcept C36036425 @default.
• W2015266979 hasConcept C500558357 @default.
• W2015266979 hasConcept C71924100 @default.
• W2015266979 hasConcept C86803240 @default.
• W2015266979 hasConcept C8880881 @default.
• W2015266979 hasConcept C956191 @default.
• W2015266979 hasConceptScore W2015266979C126322002 @default.
• W2015266979 hasConceptScore W2015266979C133927893 @default.
• W2015266979 hasConceptScore W2015266979C144469398 @default.
• W2015266979 hasConceptScore W2015266979C147483822 @default.
• W2015266979 hasConceptScore W2015266979C153911025 @default.
• W2015266979 hasConceptScore W2015266979C159654299 @default.
• W2015266979 hasConceptScore W2015266979C164705383 @default.
• W2015266979 hasConceptScore W2015266979C185592680 @default.
• W2015266979 hasConceptScore W2015266979C203014093 @default.
• W2015266979 hasConceptScore W2015266979C36036425 @default.
• W2015266979 hasConceptScore W2015266979C500558357 @default.
• W2015266979 hasConceptScore W2015266979C71924100 @default.
• W2015266979 hasConceptScore W2015266979C86803240 @default.
• W2015266979 hasConceptScore W2015266979C8880881 @default.
• W2015266979 hasConceptScore W2015266979C956191 @default.
• W2015266979 hasIssue "12" @default.
• W2015266979 hasLocation W20152669791 @default.
• W2015266979 hasLocation W20152669792 @default.
• W2015266979 hasOpenAccess W2015266979 @default.
• W2015266979 hasPrimaryLocation W20152669791 @default.
• W2015266979 hasRelatedWork W1863553834 @default.
• W2015266979 hasRelatedWork W1993423515 @default.
• W2015266979 hasRelatedWork W2013195452 @default.
• W2015266979 hasRelatedWork W2058525629 @default.
• W2015266979 hasRelatedWork W2082155590 @default.
• W2015266979 hasRelatedWork W2334709023 @default.
• W2015266979 hasRelatedWork W2346785564 @default.

• next