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- W2015273018 abstract "A procedure is described that provides co-immobilization of enzyme and bovine serum albumin (BSA) within an alumina sol–gel matrix and a polyphenol layer permselective for endogenous electroactive species. BSA has first been employed for the immobilization of glucose oxidase (GOx) on a Pt electrode in a sol–gel to produce a uniform, thin and compact film with enhanced enzyme activity. Electropolymerization of phenol was then employed to form an anti-interference and protective polyphenol film within the enzyme layer. In addition, a stability-reinforcing membrane derived from (3-aminopropyl)-trimethoxysilane was constructed by electrochemically-assisted crosslinking. This hybrid film outside the enzyme layer contributed both to the improved stability and to permselectivity. The resulting glucose sensor was characterized by a short response time (<10 s), high sensitivity (10.4 nA/mM mm2), low interference from endogenous electroactive species, and a working lifetime of at least 60 days." @default.
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- W2015273018 date "2002-12-01" @default.
- W2015273018 modified "2023-10-11" @default.
- W2015273018 title "Glucose microbiosensor based on alumina sol–gel matrix/electropolymerized composite membrane" @default.
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- W2015273018 doi "https://doi.org/10.1016/s0956-5663(02)00093-3" @default.
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