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- W2015280190 abstract "Most beta-1,4-galactosyltransferase (beta-1,4-GalT)-knockout mice die after birth. Although several defects were found transiently in these animals, the primary cause of death is obscure. Not only beta-1,4-linked galactose residues on N-glycans, but also beta-1, 4-GalT activities were found in some of the tissues. Recently, five human genes which encode beta-1,4-GalTs have been cloned, and the possible presence of such novel beta-1,4-GalTs in mice is considered to bring about survival of the mutant animal beyond birth. In order to understand the semi-lethal nature of this animal, it is inevitable to clarify how individual novel beta-1,4-GalTs are involved in the biosynthesis of glycoconjugates based on their acceptor-substrate specificities." @default.
- W2015280190 created "2016-06-24" @default.
- W2015280190 creator A5051199077 @default.
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- W2015280190 date "1999-12-01" @default.
- W2015280190 modified "2023-10-10" @default.
- W2015280190 title "β-1,4-Galactosylation of N-glycans is a complex process" @default.
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- W2015280190 doi "https://doi.org/10.1016/s0304-4165(99)00169-5" @default.
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