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• W2015296963 abstract "Little is known of the incidence, predictors or outcomes of luteal phase pregnancies (LPPs) in women presenting for voluntary interval female sterilization. A series of 37 LPPs was identified from a large multicenter female sterilization data set. Each LPP case was matched with two nonpregnant (NP) controls for clinic, operator, surgical approach, tubal occlusion technique and date of surgery. The LPP cases did not have a distinct demographic or clinical profile, but were generally more fecund than NP controls. LPPs were further compared with a second unmatched group consisting of 123 true sterilization failures (TSFs), pregnancies conceived after sterilization. Women with LPPs were more likely to have their pregnancies confirmed and/or terminated in the second trimester than were women with TSFs. The majority of LPPs were carried to term; the majority of TSFs ended in induced abortion. There were 12 ruptured ectopic pregnancies among the TSFs and none among the LPPs. Programmatic implications of the results are discussed.8% to 58% of all pregnancies reported after sterilizations are actually conceived undetected by the woman or the surgeon before sterilization is performed. These are the so-called luteal phase pregnancies (LPP). This study examines the natural history of LPPs in terms of magnitude of the problem, associated risk factors, and pregnancy outcomes. 37 LPPs reported from 20 of 69 clinics participating in multicenter female sterilization studies by the IFRP (International Fertility Research Program) were used as basis for analysis. To determine the salient risk factors, matched triplets were formed. Each LPP case was matched with 2 interval sterilization nonpregnant controls (NP). Cases and controls were matched for identical center, operator, surgical approach and tubal occlusion technique. Controls were further matched for date of surgery. Another group of 123 who conceived after an interval sterilization procedure (true sterilization failures, or TSFs) was used for comparison. The LPPs comprised 14.4% of the total number of confirmed pregnancies in the IFRP data set and 23.0% of confirmed pregnancies following interval sterilization procedures. Incidence of LPPs is 2.3/1000 interval procedures (1.6/1000 procedures overall). There were no significant differences between LPPs and NP controls as far as demographic or clinical characteristics are concerned. The interval between the most recent pregnancy and sterilization in 72.2% of the cases and in 48.6% of the matched controls is less than 2 years, giving a matched odds ratio of 2.8 (p0.05). The LPP cases were generally more fecund than NP controls. 18 of 33 LPPs (54.5%) but only 9 of 100 TSF pregnancies ended in live birth, indicating that women with LPPs were more likely to carry their pregnancies to term; most of the TSFs ended in induced abortion. Ruptured ectopic pregnancy occurred in none of the cases but in 12 of controls (12.0%; p=0.037 by Fisher's exact test). Incidence of spontaneous abortion was similar in both groups. The study supports a causal association between female sterilization procedures and subsequent ectopic pregnancy." @default.
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• W2015296963 date "1981-06-01" @default.
• W2015296963 modified "2023-09-25" @default.
• W2015296963 title "Luteal phase pregnancies in female sterilization patients" @default.
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• W2015296963 doi "https://doi.org/10.1016/s0010-7824(81)80001-7" @default.
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