Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015300267> ?p ?o ?g. }
- W2015300267 endingPage "731" @default.
- W2015300267 startingPage "723" @default.
- W2015300267 abstract "Mesoporous hydroxyapatite (HA) rod-like nanocrystals (MHANs) with large and tunable mesopores and small particle sizes were synthesized using a novel bioinspired route where mesoporous silica nanoparticles (MSNs) acted as effective nucleating agents, and fetuin (an abundant serum protein) inhibited the growth of HA. Under the cooperative influences of the MSNs and fetuin, the nucleation and growth processes of MHANs were effectively controlled such that nanosized HA crystals with dumbbell morphologies, mesoporous structures, and large surface areas were produced. This synthetic strategy was also controllable such that MHANs with particle sizes of 235–515 nm, pore sizes of 21.1–30.5 nm, and surface areas of 130–225 m2 g–1 could be systematically produced by tuning the fetuin concentration. The MHANs were then investigated as drug delivery vehicles and exhibited a high loading capacity and sustained release of large pharmaceutics, as shown through a model large-molecule protein. Demonstration of effective intracellular uptake and low cytotoxicity confirmed the potential of the MHANs as carriers of large pharmaceutics." @default.
- W2015300267 created "2016-06-24" @default.
- W2015300267 creator A5025513043 @default.
- W2015300267 creator A5046331790 @default.
- W2015300267 creator A5048988670 @default.
- W2015300267 creator A5069772530 @default.
- W2015300267 date "2015-01-08" @default.
- W2015300267 modified "2023-10-08" @default.
- W2015300267 title "Bioinspired Synthesis of Large-Pore, Mesoporous Hydroxyapatite Nanocrystals for the Controlled Release of Large Pharmaceutics" @default.
- W2015300267 cites W1531846676 @default.
- W2015300267 cites W1968642915 @default.
- W2015300267 cites W1973948354 @default.
- W2015300267 cites W1978975755 @default.
- W2015300267 cites W1987995270 @default.
- W2015300267 cites W1990216816 @default.
- W2015300267 cites W1992959003 @default.
- W2015300267 cites W1996629366 @default.
- W2015300267 cites W2007574249 @default.
- W2015300267 cites W2009760086 @default.
- W2015300267 cites W2012202041 @default.
- W2015300267 cites W2014523572 @default.
- W2015300267 cites W2016613065 @default.
- W2015300267 cites W2018613635 @default.
- W2015300267 cites W2020249973 @default.
- W2015300267 cites W2025608974 @default.
- W2015300267 cites W2028279176 @default.
- W2015300267 cites W2029496340 @default.
- W2015300267 cites W2031833830 @default.
- W2015300267 cites W2042631295 @default.
- W2015300267 cites W2048379336 @default.
- W2015300267 cites W2060159611 @default.
- W2015300267 cites W2060887828 @default.
- W2015300267 cites W2065024557 @default.
- W2015300267 cites W2075946855 @default.
- W2015300267 cites W2077598490 @default.
- W2015300267 cites W2078616336 @default.
- W2015300267 cites W2079860226 @default.
- W2015300267 cites W2091321736 @default.
- W2015300267 cites W2104963758 @default.
- W2015300267 cites W2107423984 @default.
- W2015300267 cites W2112697750 @default.
- W2015300267 cites W2113972541 @default.
- W2015300267 cites W2119601969 @default.
- W2015300267 cites W2123432729 @default.
- W2015300267 cites W2133295971 @default.
- W2015300267 cites W2138861644 @default.
- W2015300267 cites W2155961206 @default.
- W2015300267 cites W2159210886 @default.
- W2015300267 cites W2162949380 @default.
- W2015300267 cites W2166903030 @default.
- W2015300267 cites W2167455623 @default.
- W2015300267 cites W2318092425 @default.
- W2015300267 cites W2328251793 @default.
- W2015300267 doi "https://doi.org/10.1021/cg501515c" @default.
- W2015300267 hasPublicationYear "2015" @default.
- W2015300267 type Work @default.
- W2015300267 sameAs 2015300267 @default.
- W2015300267 citedByCount "30" @default.
- W2015300267 countsByYear W20153002672015 @default.
- W2015300267 countsByYear W20153002672016 @default.
- W2015300267 countsByYear W20153002672017 @default.
- W2015300267 countsByYear W20153002672018 @default.
- W2015300267 countsByYear W20153002672019 @default.
- W2015300267 countsByYear W20153002672020 @default.
- W2015300267 countsByYear W20153002672021 @default.
- W2015300267 countsByYear W20153002672022 @default.
- W2015300267 countsByYear W20153002672023 @default.
- W2015300267 crossrefType "journal-article" @default.
- W2015300267 hasAuthorship W2015300267A5025513043 @default.
- W2015300267 hasAuthorship W2015300267A5046331790 @default.
- W2015300267 hasAuthorship W2015300267A5048988670 @default.
- W2015300267 hasAuthorship W2015300267A5069772530 @default.
- W2015300267 hasConcept C111368507 @default.
- W2015300267 hasConcept C127313418 @default.
- W2015300267 hasConcept C127413603 @default.
- W2015300267 hasConcept C13245373 @default.
- W2015300267 hasConcept C138651985 @default.
- W2015300267 hasConcept C155672457 @default.
- W2015300267 hasConcept C161790260 @default.
- W2015300267 hasConcept C163588942 @default.
- W2015300267 hasConcept C171250308 @default.
- W2015300267 hasConcept C178790620 @default.
- W2015300267 hasConcept C185592680 @default.
- W2015300267 hasConcept C192562407 @default.
- W2015300267 hasConcept C2777496208 @default.
- W2015300267 hasConcept C2778517922 @default.
- W2015300267 hasConcept C2779820397 @default.
- W2015300267 hasConcept C42360764 @default.
- W2015300267 hasConcept C61048295 @default.
- W2015300267 hasConcept C71924100 @default.
- W2015300267 hasConcept C82776694 @default.
- W2015300267 hasConcept C98274493 @default.
- W2015300267 hasConceptScore W2015300267C111368507 @default.
- W2015300267 hasConceptScore W2015300267C127313418 @default.
- W2015300267 hasConceptScore W2015300267C127413603 @default.
- W2015300267 hasConceptScore W2015300267C13245373 @default.
- W2015300267 hasConceptScore W2015300267C138651985 @default.
- W2015300267 hasConceptScore W2015300267C155672457 @default.