FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015305248> ?p ?o ?g. }

• W2015305248 abstract "Classical swine fever virus (CSFV) is the causative agent of classical swine fever (CSF), a highly contagious fatal disease of swine. Few effective antiviral drugs are currently available against CSFV infections. To explore the feasibility of using capsid-targeted viral inactivation (CTVI) as an antiviral strategy against CSFV infections, we expressed the CSFV capsid protein (Cap) fused with the nuclease of Staphylococcus aureus (SN) in Escherichia coli and investigated its effects on the replication of CSFV in PK-15 cells. The results indicated that the fusion protein Cap-SN showed a strong Ca(2+)-dependent nuclease activity and inhibited the replication of CSFV in a dose-dependent manner, with complete inhibition at a concentration of 15 microg/ml, whereas the Cap fused with an enzymatically inactive SN (Cap-SN*) showed no nuclease activity or antiviral effects. Thus, the CTVI approach might be applicable to CSFV inhibition as a novel antiviral strategy." @default.
• W2015305248 created "2016-06-24" @default.
• W2015305248 creator A5020315365 @default.
• W2015305248 creator A5035182164 @default.
• W2015305248 creator A5038805449 @default.
• W2015305248 creator A5046694705 @default.
• W2015305248 creator A5061407463 @default.
• W2015305248 creator A5062321435 @default.
• W2015305248 creator A5088783224 @default.
• W2015305248 date "2010-02-01" @default.
• W2015305248 modified "2023-09-23" @default.
• W2015305248 title "In vitro inhibition of the replication of classical swine fever virus by capsid-targeted virus inactivation" @default.
• W2015305248 cites W1964896501 @default.
• W2015305248 cites W1967539989 @default.
• W2015305248 cites W1973254364 @default.
• W2015305248 cites W1983064802 @default.
• W2015305248 cites W1990771267 @default.
• W2015305248 cites W2008741507 @default.
• W2015305248 cites W2024080387 @default.
• W2015305248 cites W2025726431 @default.
• W2015305248 cites W2030368438 @default.
• W2015305248 cites W2076240008 @default.
• W2015305248 cites W2082176485 @default.
• W2015305248 cites W2090337704 @default.
• W2015305248 cites W2097074859 @default.
• W2015305248 cites W2102988971 @default.
• W2015305248 cites W2105668301 @default.
• W2015305248 cites W2136497869 @default.
• W2015305248 cites W2137977382 @default.
• W2015305248 cites W2158896168 @default.
• W2015305248 cites W2180431510 @default.
• W2015305248 cites W2322598044 @default.
• W2015305248 cites W3159921398 @default.
• W2015305248 cites W84204737 @default.
• W2015305248 doi "https://doi.org/10.1016/j.antiviral.2009.10.010" @default.
• W2015305248 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19857524" @default.
• W2015305248 hasPublicationYear "2010" @default.
• W2015305248 type Work @default.
• W2015305248 sameAs 2015305248 @default.
• W2015305248 citedByCount "7" @default.
• W2015305248 countsByYear W20153052482012 @default.
• W2015305248 countsByYear W20153052482013 @default.
• W2015305248 countsByYear W20153052482016 @default.
• W2015305248 countsByYear W20153052482019 @default.
• W2015305248 crossrefType "journal-article" @default.
• W2015305248 hasAuthorship W2015305248A5020315365 @default.
• W2015305248 hasAuthorship W2015305248A5035182164 @default.
• W2015305248 hasAuthorship W2015305248A5038805449 @default.
• W2015305248 hasAuthorship W2015305248A5046694705 @default.
• W2015305248 hasAuthorship W2015305248A5061407463 @default.
• W2015305248 hasAuthorship W2015305248A5062321435 @default.
• W2015305248 hasAuthorship W2015305248A5088783224 @default.
• W2015305248 hasConcept C104317684 @default.
• W2015305248 hasConcept C140704245 @default.
• W2015305248 hasConcept C159047783 @default.
• W2015305248 hasConcept C202751555 @default.
• W2015305248 hasConcept C202878990 @default.
• W2015305248 hasConcept C2522874641 @default.
• W2015305248 hasConcept C2777271071 @default.
• W2015305248 hasConcept C2779005923 @default.
• W2015305248 hasConcept C2779489039 @default.
• W2015305248 hasConcept C523546767 @default.
• W2015305248 hasConcept C54355233 @default.
• W2015305248 hasConcept C547475151 @default.
• W2015305248 hasConcept C552990157 @default.
• W2015305248 hasConcept C55493867 @default.
• W2015305248 hasConcept C86803240 @default.
• W2015305248 hasConcept C89423630 @default.
• W2015305248 hasConceptScore W2015305248C104317684 @default.
• W2015305248 hasConceptScore W2015305248C140704245 @default.
• W2015305248 hasConceptScore W2015305248C159047783 @default.
• W2015305248 hasConceptScore W2015305248C202751555 @default.
• W2015305248 hasConceptScore W2015305248C202878990 @default.
• W2015305248 hasConceptScore W2015305248C2522874641 @default.
• W2015305248 hasConceptScore W2015305248C2777271071 @default.
• W2015305248 hasConceptScore W2015305248C2779005923 @default.
• W2015305248 hasConceptScore W2015305248C2779489039 @default.
• W2015305248 hasConceptScore W2015305248C523546767 @default.
• W2015305248 hasConceptScore W2015305248C54355233 @default.
• W2015305248 hasConceptScore W2015305248C547475151 @default.
• W2015305248 hasConceptScore W2015305248C552990157 @default.
• W2015305248 hasConceptScore W2015305248C55493867 @default.
• W2015305248 hasConceptScore W2015305248C86803240 @default.
• W2015305248 hasConceptScore W2015305248C89423630 @default.
• W2015305248 hasLocation W20153052481 @default.
• W2015305248 hasLocation W20153052482 @default.
• W2015305248 hasOpenAccess W2015305248 @default.
• W2015305248 hasPrimaryLocation W20153052481 @default.
• W2015305248 hasRelatedWork W1968289271 @default.
• W2015305248 hasRelatedWork W1970961865 @default.
• W2015305248 hasRelatedWork W1971798850 @default.
• W2015305248 hasRelatedWork W2018973176 @default.
• W2015305248 hasRelatedWork W2024043489 @default.
• W2015305248 hasRelatedWork W2032295666 @default.
• W2015305248 hasRelatedWork W2051743812 @default.
• W2015305248 hasRelatedWork W2062474640 @default.
• W2015305248 hasRelatedWork W2090337704 @default.
• W2015305248 hasRelatedWork W2104118102 @default.
• W2015305248 hasRelatedWork W2157687716 @default.
• W2015305248 hasRelatedWork W2162693599 @default.

• next