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• W2015315215 abstract "A heuristic approximation to the score distribution of gapped alignments in the logarithmic domain is presented. The method applies to comparisons between random, unrelated protein sequences, using standard score matrices and arbitrary gap penalties. It is shown that gapped alignment behavior is essentially governed by a single parameter, α, depending on the penalty scheme and sequence composition. This treatment also predicts the position of the transition point between logarithmic and linear behavior. The approximation is tested by simulation and shown to be accurate over a range of commonly used substitution matrices and gap-penalties." @default.
• W2015315215 created "2016-06-24" @default.
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• W2015315215 date "1999-01-01" @default.
• W2015315215 modified "2023-09-23" @default.
• W2015315215 title "Approximate Statistics of Gapped Alignments" @default.
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• W2015315215 doi "https://doi.org/10.1089/cmb.1999.6.91" @default.
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