FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015343223> ?p ?o ?g. }

• W2015343223 endingPage "671" @default.
• W2015343223 startingPage "661" @default.
• W2015343223 abstract "Randomized controlled trial with single-blinded primary outcome assessment. To determine the efficacy and safety of autologous incubated macrophage treatment for improving neurological outcome in patients with acute, complete spinal cord injury (SCI). Six SCI treatment centers in the United States and Israel. Participants with traumatic complete SCI between C5 motor and T11 neurological levels who could receive macrophage therapy within 14 days of injury were randomly assigned in a 2:1 ratio to the treatment (autologous incubated macrophages) or control (standard of care) groups. Treatment group participants underwent macrophage injection into the caudal boundary of the SCI. The primary outcome measure was American Spinal Injury Association (ASIA) Impairment Scale (AIS) A–B or better at ⩾6 months. Safety was assessed by analysis of adverse events (AEs). Of 43 participants (26 treatment, 17 control) having sufficient data for efficacy analysis, AIS A to B or better conversion was experienced by 7 treatment and 10 control participants; AIS A to C conversion was experienced by 2 treatment and 2 control participants. The primary outcome analysis for subjects with at least 6 months follow-up showed a trend favoring the control group that did not achieve statistical significance (P=0.053). The mean number of AEs reported per participant was not significantly different between the groups (P=0.942). The analysis failed to show a significant difference in primary outcome between the two groups. The study results do not support treatment of acute complete SCI with autologous incubated macrophage therapy as specified in this protocol." @default.
• W2015343223 created "2016-06-24" @default.
• W2015343223 creator A5009710216 @default.
• W2015343223 creator A5010997955 @default.
• W2015343223 creator A5013373285 @default.
• W2015343223 creator A5018359512 @default.
• W2015343223 creator A5020135297 @default.
• W2015343223 creator A5024049076 @default.
• W2015343223 creator A5027599882 @default.
• W2015343223 creator A5027830983 @default.
• W2015343223 creator A5031679159 @default.
• W2015343223 creator A5038949736 @default.
• W2015343223 creator A5042380113 @default.
• W2015343223 creator A5046151553 @default.
• W2015343223 creator A5049794005 @default.
• W2015343223 creator A5066600594 @default.
• W2015343223 creator A5070027700 @default.
• W2015343223 creator A5070266815 @default.
• W2015343223 date "2012-04-24" @default.
• W2015343223 modified "2023-10-18" @default.
• W2015343223 title "Autologous incubated macrophage therapy in acute, complete spinal cord injury: results of the phase 2 randomized controlled multicenter trial" @default.
• W2015343223 cites W1509430142 @default.
• W2015343223 cites W1625824075 @default.
• W2015343223 cites W1887047158 @default.
• W2015343223 cites W1986913334 @default.
• W2015343223 cites W2039334993 @default.
• W2015343223 cites W2055273591 @default.
• W2015343223 cites W2064695347 @default.
• W2015343223 cites W2071582385 @default.
• W2015343223 cites W2083946660 @default.
• W2015343223 cites W2090854960 @default.
• W2015343223 cites W2099359509 @default.
• W2015343223 cites W2112389341 @default.
• W2015343223 cites W2120528281 @default.
• W2015343223 cites W2122305954 @default.
• W2015343223 cites W2130529018 @default.
• W2015343223 cites W2161456562 @default.
• W2015343223 cites W2166125615 @default.
• W2015343223 cites W4299727233 @default.
• W2015343223 doi "https://doi.org/10.1038/sc.2012.39" @default.
• W2015343223 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22525310" @default.
• W2015343223 hasPublicationYear "2012" @default.
• W2015343223 type Work @default.
• W2015343223 sameAs 2015343223 @default.
• W2015343223 citedByCount "119" @default.
• W2015343223 countsByYear W20153432232012 @default.
• W2015343223 countsByYear W20153432232013 @default.
• W2015343223 countsByYear W20153432232014 @default.
• W2015343223 countsByYear W20153432232015 @default.
• W2015343223 countsByYear W20153432232016 @default.
• W2015343223 countsByYear W20153432232017 @default.
• W2015343223 countsByYear W20153432232018 @default.
• W2015343223 countsByYear W20153432232019 @default.
• W2015343223 countsByYear W20153432232020 @default.
• W2015343223 countsByYear W20153432232021 @default.
• W2015343223 countsByYear W20153432232022 @default.
• W2015343223 countsByYear W20153432232023 @default.
• W2015343223 crossrefType "journal-article" @default.
• W2015343223 hasAuthorship W2015343223A5009710216 @default.
• W2015343223 hasAuthorship W2015343223A5010997955 @default.
• W2015343223 hasAuthorship W2015343223A5013373285 @default.
• W2015343223 hasAuthorship W2015343223A5018359512 @default.
• W2015343223 hasAuthorship W2015343223A5020135297 @default.
• W2015343223 hasAuthorship W2015343223A5024049076 @default.
• W2015343223 hasAuthorship W2015343223A5027599882 @default.
• W2015343223 hasAuthorship W2015343223A5027830983 @default.
• W2015343223 hasAuthorship W2015343223A5031679159 @default.
• W2015343223 hasAuthorship W2015343223A5038949736 @default.
• W2015343223 hasAuthorship W2015343223A5042380113 @default.
• W2015343223 hasAuthorship W2015343223A5046151553 @default.
• W2015343223 hasAuthorship W2015343223A5049794005 @default.
• W2015343223 hasAuthorship W2015343223A5066600594 @default.
• W2015343223 hasAuthorship W2015343223A5070027700 @default.
• W2015343223 hasAuthorship W2015343223A5070266815 @default.
• W2015343223 hasBestOaLocation W20153432231 @default.
• W2015343223 hasConcept C118552586 @default.
• W2015343223 hasConcept C126322002 @default.
• W2015343223 hasConcept C141071460 @default.
• W2015343223 hasConcept C168563851 @default.
• W2015343223 hasConcept C1862650 @default.
• W2015343223 hasConcept C197934379 @default.
• W2015343223 hasConcept C2778334475 @default.
• W2015343223 hasConcept C2780775167 @default.
• W2015343223 hasConcept C535046627 @default.
• W2015343223 hasConcept C65409693 @default.
• W2015343223 hasConcept C71924100 @default.
• W2015343223 hasConceptScore W2015343223C118552586 @default.
• W2015343223 hasConceptScore W2015343223C126322002 @default.
• W2015343223 hasConceptScore W2015343223C141071460 @default.
• W2015343223 hasConceptScore W2015343223C168563851 @default.
• W2015343223 hasConceptScore W2015343223C1862650 @default.
• W2015343223 hasConceptScore W2015343223C197934379 @default.
• W2015343223 hasConceptScore W2015343223C2778334475 @default.
• W2015343223 hasConceptScore W2015343223C2780775167 @default.
• W2015343223 hasConceptScore W2015343223C535046627 @default.
• W2015343223 hasConceptScore W2015343223C65409693 @default.
• W2015343223 hasConceptScore W2015343223C71924100 @default.
• W2015343223 hasIssue "9" @default.

• next