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- W2015344326 abstract "McCall WV, Reboussin DM, Weiner RD, et al. Titrated moderately suprathreshold vs fixed high-dose right unilateral electroconvulsive therapy: acute antidepressant and cognitive effects . Arch Gen Psychiatry2000 May; 57 : 438 –44. [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] QUESTION: In patients with a major depressive disorder (MDD), how do titrated moderately suprathreshold and fixed high dose right unilateral (RUL) electroconvulsive therapy (ECT) compare for acute antidepressant response and cognitive side effects? Randomised {allocation concealed*}†, blinded ({treatment team, patients}†, and outcome assessors),* controlled trial with 1–2 days of follow up after the last RUL ECT session. Tertiary care centre in Winston-Salem, North Carolina, USA. 72 patients (90% outpatients) who were ≥18 years of age (mean age 64 y, 75% women) and met DSM-III-R criteria for MDD. Exclusion criteria were a history of functional psychosis, active substance abuse, mental retardation or neurological illness, ECT in the past 4 months, score of <18 on the Mini-Mental State Examination (MMSE), score of <20 on the Hamilton Rating Scale for Depression (HRSD), need for bilateral ECT because of extreme severity of illness, refusal to cooperate with testing, or predominantly left handedness. Follow up was complete for antidepressant response and 88% for cognitive side effects. RUL ECT seizure threshold (ST) … [1]: {openurl}?query=rft.jtitle%253DArchives%2Bof%2BGeneral%2BPsychiatry%26rft.stitle%253DArch%2BGen%2BPsychiatry%26rft.aulast%253DMcCall%26rft.auinit1%253DW.%2BV.%26rft.volume%253D57%26rft.issue%253D5%26rft.spage%253D438%26rft.epage%253D444%26rft.atitle%253DTitrated%2BModerately%2BSuprathreshold%2Bvs%2BFixed%2BHigh-Dose%2BRight%2BUnilateral%2BElectroconvulsive%2BTherapy%253A%2BAcute%2BAntidepressant%2Band%2BCognitive%2BEffects%26rft_id%253Dinfo%253Adoi%252F10.1001%252Farchpsyc.57.5.438%26rft_id%253Dinfo%253Apmid%252F10807483%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1001/archpsyc.57.5.438&link_type=DOI [3]: /lookup/external-ref?access_num=10807483&link_type=MED&atom=%2Febmental%2F3%2F4%2F114.atom [4]: /lookup/external-ref?access_num=000086927500002&link_type=ISI" @default.
- W2015344326 created "2016-06-24" @default.
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- W2015344326 date "2000-11-01" @default.
- W2015344326 modified "2023-10-16" @default.
- W2015344326 title "Fixed high dose right unilateral electroconvulsive therapy produced a higher antidepressant response rate than titrated dosing" @default.
- W2015344326 cites W2018390248 @default.
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- W2015344326 doi "https://doi.org/10.1136/ebmh.3.4.114" @default.
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