Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015376265> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2015376265 endingPage "158" @default.
- W2015376265 startingPage "155" @default.
- W2015376265 abstract "Natural killer (NK) activity is a poorly understood component of the immune system, generally identified as the ability to kill certain tumour cells1,2. Perhaps the most controversial issue has been the lineage to which cells displaying this activity belong. Extensive studies of surface antigens on cells with NK activity in both mouse and man have led to enigmatic results, such cells apparently bearing markers of both T-cell (Thy-1 and E receptor) and myeloid (Mac-1 and OKM1) lineages3–6. A fresh approach to this problem would be to take cells of known lineage and test whether they express, or could be induced to express, NK cell function. Using this approach we show here that monoclonal cytotoxic T lymphocyte (CTL) lines can be induced, by culture in high concentrations of spleen cell supernatant, to express a new lytic activity apparently identical with that of splenic cells NK activity. Preliminary evidence implicates both interleukin-2(IL-2) and interferon (IFN) as mediators of this phenomenon. These findings clearly demonstrate that cells of T cell lineage have the capacity to express NK activity." @default.
- W2015376265 created "2016-06-24" @default.
- W2015376265 creator A5045752749 @default.
- W2015376265 date "1983-09-01" @default.
- W2015376265 modified "2023-10-10" @default.
- W2015376265 title "Reversible induction of natural killer cell activity in cloned murine cytotoxic T lymphocytes" @default.
- W2015376265 cites W1482804511 @default.
- W2015376265 cites W1489781915 @default.
- W2015376265 cites W1532019605 @default.
- W2015376265 cites W1582783112 @default.
- W2015376265 cites W1907353691 @default.
- W2015376265 cites W1912676133 @default.
- W2015376265 cites W1955661374 @default.
- W2015376265 cites W1959011963 @default.
- W2015376265 cites W1979343444 @default.
- W2015376265 cites W1993319836 @default.
- W2015376265 cites W2005770085 @default.
- W2015376265 cites W2012231676 @default.
- W2015376265 cites W2021102872 @default.
- W2015376265 cites W2027335406 @default.
- W2015376265 cites W2027791907 @default.
- W2015376265 cites W2065704811 @default.
- W2015376265 cites W2102386308 @default.
- W2015376265 cites W2150907854 @default.
- W2015376265 cites W2162224300 @default.
- W2015376265 cites W2171460503 @default.
- W2015376265 cites W51471118 @default.
- W2015376265 doi "https://doi.org/10.1038/305155a0" @default.
- W2015376265 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7094994" @default.
- W2015376265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6604229" @default.
- W2015376265 hasPublicationYear "1983" @default.
- W2015376265 type Work @default.
- W2015376265 sameAs 2015376265 @default.
- W2015376265 citedByCount "133" @default.
- W2015376265 crossrefType "journal-article" @default.
- W2015376265 hasAuthorship W2015376265A5045752749 @default.
- W2015376265 hasBestOaLocation W20153762651 @default.
- W2015376265 hasConcept C129374314 @default.
- W2015376265 hasConcept C139563560 @default.
- W2015376265 hasConcept C147969180 @default.
- W2015376265 hasConcept C149532602 @default.
- W2015376265 hasConcept C154317977 @default.
- W2015376265 hasConcept C182615771 @default.
- W2015376265 hasConcept C202751555 @default.
- W2015376265 hasConcept C203014093 @default.
- W2015376265 hasConcept C2522874641 @default.
- W2015376265 hasConcept C2776090121 @default.
- W2015376265 hasConcept C2778102761 @default.
- W2015376265 hasConcept C2780931953 @default.
- W2015376265 hasConcept C28651165 @default.
- W2015376265 hasConcept C54355233 @default.
- W2015376265 hasConcept C86803240 @default.
- W2015376265 hasConcept C8891405 @default.
- W2015376265 hasConcept C95444343 @default.
- W2015376265 hasConceptScore W2015376265C129374314 @default.
- W2015376265 hasConceptScore W2015376265C139563560 @default.
- W2015376265 hasConceptScore W2015376265C147969180 @default.
- W2015376265 hasConceptScore W2015376265C149532602 @default.
- W2015376265 hasConceptScore W2015376265C154317977 @default.
- W2015376265 hasConceptScore W2015376265C182615771 @default.
- W2015376265 hasConceptScore W2015376265C202751555 @default.
- W2015376265 hasConceptScore W2015376265C203014093 @default.
- W2015376265 hasConceptScore W2015376265C2522874641 @default.
- W2015376265 hasConceptScore W2015376265C2776090121 @default.
- W2015376265 hasConceptScore W2015376265C2778102761 @default.
- W2015376265 hasConceptScore W2015376265C2780931953 @default.
- W2015376265 hasConceptScore W2015376265C28651165 @default.
- W2015376265 hasConceptScore W2015376265C54355233 @default.
- W2015376265 hasConceptScore W2015376265C86803240 @default.
- W2015376265 hasConceptScore W2015376265C8891405 @default.
- W2015376265 hasConceptScore W2015376265C95444343 @default.
- W2015376265 hasIssue "5930" @default.
- W2015376265 hasLocation W20153762651 @default.
- W2015376265 hasLocation W20153762652 @default.
- W2015376265 hasLocation W20153762653 @default.
- W2015376265 hasLocation W20153762654 @default.
- W2015376265 hasOpenAccess W2015376265 @default.
- W2015376265 hasPrimaryLocation W20153762651 @default.
- W2015376265 hasRelatedWork W1483170373 @default.
- W2015376265 hasRelatedWork W1629874984 @default.
- W2015376265 hasRelatedWork W199336330 @default.
- W2015376265 hasRelatedWork W2019540920 @default.
- W2015376265 hasRelatedWork W2020960833 @default.
- W2015376265 hasRelatedWork W2043316228 @default.
- W2015376265 hasRelatedWork W2066698655 @default.
- W2015376265 hasRelatedWork W2475299811 @default.
- W2015376265 hasRelatedWork W2771789930 @default.
- W2015376265 hasRelatedWork W394065362 @default.
- W2015376265 hasVolume "305" @default.
- W2015376265 isParatext "false" @default.
- W2015376265 isRetracted "false" @default.
- W2015376265 magId "2015376265" @default.
- W2015376265 workType "article" @default.