FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015377937> ?p ?o ?g. }

• W2015377937 endingPage "7166" @default.
• W2015377937 startingPage "7159" @default.
• W2015377937 abstract "Significant changes in anti-pneumococcal polysaccharide (PPS) variable gene usage occur with aging and may be influenced by changes in cytokine environment. Severe combined immunodeficient (SCID) mice were engrafted with B cells obtained from young and elderly donors, supplemented with human cytokines and immunized with the pneumococcal polysaccharide vaccine. B cells specific for PPS serotypes 4 and 14 were isolated from mice and immunized donors, and variable region sequences analyzed. Significant differences in variable heavy and light chain gene usage were observed between young and elderly adults despite a more constant cytokine environment. Due to the limitations of the hu-PBL-SCID model, the use of alternative systems would be beneficial in the elucidation of mechanisms underlying the reduced vaccine efficacy in the elderly." @default.
• W2015377937 created "2016-06-24" @default.
• W2015377937 creator A5001515839 @default.
• W2015377937 creator A5007653905 @default.
• W2015377937 creator A5019897123 @default.
• W2015377937 creator A5028511545 @default.
• W2015377937 creator A5082857268 @default.
• W2015377937 date "2006-11-01" @default.
• W2015377937 modified "2023-10-16" @default.
• W2015377937 title "Analysis of the young and elderly variable gene repertoire in response to pneumococcal polysaccharides using a reconstituted SCID mouse model" @default.
• W2015377937 cites W1577104641 @default.
• W2015377937 cites W1831981047 @default.
• W2015377937 cites W1903636206 @default.
• W2015377937 cites W2006823107 @default.
• W2015377937 cites W2021916493 @default.
• W2015377937 cites W2024123171 @default.
• W2015377937 cites W2055291559 @default.
• W2015377937 cites W2060290587 @default.
• W2015377937 cites W2083869737 @default.
• W2015377937 cites W2084857996 @default.
• W2015377937 cites W2087106007 @default.
• W2015377937 cites W2101655599 @default.
• W2015377937 cites W2105388631 @default.
• W2015377937 cites W2108862543 @default.
• W2015377937 cites W2121228279 @default.
• W2015377937 cites W2123619196 @default.
• W2015377937 cites W2130994987 @default.
• W2015377937 cites W2146439877 @default.
• W2015377937 cites W2146603963 @default.
• W2015377937 cites W2146643550 @default.
• W2015377937 cites W2152670961 @default.
• W2015377937 cites W2168379509 @default.
• W2015377937 cites W2342228817 @default.
• W2015377937 cites W4233948292 @default.
• W2015377937 cites W4248556068 @default.
• W2015377937 cites W4313309975 @default.
• W2015377937 doi "https://doi.org/10.1016/j.vaccine.2006.06.055" @default.
• W2015377937 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16884837" @default.
• W2015377937 hasPublicationYear "2006" @default.
• W2015377937 type Work @default.
• W2015377937 sameAs 2015377937 @default.
• W2015377937 citedByCount "5" @default.
• W2015377937 countsByYear W20153779372017 @default.
• W2015377937 crossrefType "journal-article" @default.
• W2015377937 hasAuthorship W2015377937A5001515839 @default.
• W2015377937 hasAuthorship W2015377937A5007653905 @default.
• W2015377937 hasAuthorship W2015377937A5019897123 @default.
• W2015377937 hasAuthorship W2015377937A5028511545 @default.
• W2015377937 hasAuthorship W2015377937A5082857268 @default.
• W2015377937 hasConcept C100817775 @default.
• W2015377937 hasConcept C10389963 @default.
• W2015377937 hasConcept C104317684 @default.
• W2015377937 hasConcept C111599444 @default.
• W2015377937 hasConcept C159047783 @default.
• W2015377937 hasConcept C203014093 @default.
• W2015377937 hasConcept C2778690821 @default.
• W2015377937 hasConcept C2779301066 @default.
• W2015377937 hasConcept C2781253189 @default.
• W2015377937 hasConcept C501593827 @default.
• W2015377937 hasConcept C54355233 @default.
• W2015377937 hasConcept C55493867 @default.
• W2015377937 hasConcept C86803240 @default.
• W2015377937 hasConcept C8891405 @default.
• W2015377937 hasConcept C89423630 @default.
• W2015377937 hasConceptScore W2015377937C100817775 @default.
• W2015377937 hasConceptScore W2015377937C10389963 @default.
• W2015377937 hasConceptScore W2015377937C104317684 @default.
• W2015377937 hasConceptScore W2015377937C111599444 @default.
• W2015377937 hasConceptScore W2015377937C159047783 @default.
• W2015377937 hasConceptScore W2015377937C203014093 @default.
• W2015377937 hasConceptScore W2015377937C2778690821 @default.
• W2015377937 hasConceptScore W2015377937C2779301066 @default.
• W2015377937 hasConceptScore W2015377937C2781253189 @default.
• W2015377937 hasConceptScore W2015377937C501593827 @default.
• W2015377937 hasConceptScore W2015377937C54355233 @default.
• W2015377937 hasConceptScore W2015377937C55493867 @default.
• W2015377937 hasConceptScore W2015377937C86803240 @default.
• W2015377937 hasConceptScore W2015377937C8891405 @default.
• W2015377937 hasConceptScore W2015377937C89423630 @default.
• W2015377937 hasIssue "49-50" @default.
• W2015377937 hasLocation W20153779371 @default.
• W2015377937 hasLocation W20153779372 @default.
• W2015377937 hasOpenAccess W2015377937 @default.
• W2015377937 hasPrimaryLocation W20153779371 @default.
• W2015377937 hasRelatedWork W2052428793 @default.
• W2015377937 hasRelatedWork W2079583890 @default.
• W2015377937 hasRelatedWork W2104987246 @default.
• W2015377937 hasRelatedWork W2140766375 @default.
• W2015377937 hasRelatedWork W2222332478 @default.
• W2015377937 hasRelatedWork W2382739716 @default.
• W2015377937 hasRelatedWork W2883865629 @default.
• W2015377937 hasRelatedWork W3028982012 @default.
• W2015377937 hasRelatedWork W3030830861 @default.
• W2015377937 hasRelatedWork W3035380775 @default.
• W2015377937 hasVolume "24" @default.
• W2015377937 isParatext "false" @default.
• W2015377937 isRetracted "false" @default.
• W2015377937 magId "2015377937" @default.

• next