FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015384236> ?p ?o ?g. }

• W2015384236 endingPage "627" @default.
• W2015384236 startingPage "623" @default.
• W2015384236 abstract "✓ Activated leukocytes appear to be directly involved in potentiating ischemic central nervous system (CNS) injury. Adhesion of leukocytes to endothelium is essential for their migration and requires the binding of adhesion receptors of the leukocyte (CD 18) to an intercellular adhesion molecule (ICAM) on endothelium. Monoclonal antibodies to an ICAM can block leukocyte adhesion and transendothelial migration. To determine the efficacy of anti-ICAM antibody treatment in preserving neurological function after CNS ischemia, two animal models were used. A 1-mg/kg dose of anti-ICAM was given to rabbits 30 minutes before induction of ischemia either in the spinal cord using temporary aortic occlusion or in the brain using intraarterial microspheres. In this study, treatment with anti-ICAM produced a significant reduction in neurological deficits in the reversible spinal cord ischemia model but not in the irreversible brain ischemia model. This protective effect supports the active role of leukocytes in CNS reperfusion ischemic injury and offers potential for future therapy." @default.
• W2015384236 created "2016-06-24" @default.
• W2015384236 creator A5003394099 @default.
• W2015384236 creator A5009902972 @default.
• W2015384236 creator A5026498112 @default.
• W2015384236 creator A5028934169 @default.
• W2015384236 date "1991-10-01" @default.
• W2015384236 modified "2023-10-16" @default.
• W2015384236 title "Reduction of central nervous system ischemic injury by monoclonal antibody to intercellular adhesion molecule" @default.
• W2015384236 cites W1991512363 @default.
• W2015384236 cites W1998200062 @default.
• W2015384236 cites W2011513090 @default.
• W2015384236 cites W2015037737 @default.
• W2015384236 cites W2025055098 @default.
• W2015384236 cites W2034972830 @default.
• W2015384236 cites W2059229138 @default.
• W2015384236 cites W2060217665 @default.
• W2015384236 cites W2062769963 @default.
• W2015384236 cites W2064427933 @default.
• W2015384236 cites W2094233638 @default.
• W2015384236 cites W2112275835 @default.
• W2015384236 cites W2138385457 @default.
• W2015384236 cites W2151067784 @default.
• W2015384236 cites W2153450942 @default.
• W2015384236 cites W2170046397 @default.
• W2015384236 cites W2259392365 @default.
• W2015384236 doi "https://doi.org/10.3171/jns.1991.75.4.0623" @default.
• W2015384236 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1885980" @default.
• W2015384236 hasPublicationYear "1991" @default.
• W2015384236 type Work @default.
• W2015384236 sameAs 2015384236 @default.
• W2015384236 citedByCount "198" @default.
• W2015384236 countsByYear W20153842362012 @default.
• W2015384236 countsByYear W20153842362013 @default.
• W2015384236 countsByYear W20153842362014 @default.
• W2015384236 countsByYear W20153842362017 @default.
• W2015384236 countsByYear W20153842362018 @default.
• W2015384236 countsByYear W20153842362021 @default.
• W2015384236 countsByYear W20153842362022 @default.
• W2015384236 crossrefType "journal-article" @default.
• W2015384236 hasAuthorship W2015384236A5003394099 @default.
• W2015384236 hasAuthorship W2015384236A5009902972 @default.
• W2015384236 hasAuthorship W2015384236A5026498112 @default.
• W2015384236 hasAuthorship W2015384236A5028934169 @default.
• W2015384236 hasConcept C118552586 @default.
• W2015384236 hasConcept C126322002 @default.
• W2015384236 hasConcept C142724271 @default.
• W2015384236 hasConcept C159654299 @default.
• W2015384236 hasConcept C16224149 @default.
• W2015384236 hasConcept C178790620 @default.
• W2015384236 hasConcept C185592680 @default.
• W2015384236 hasConcept C185946421 @default.
• W2015384236 hasConcept C203014093 @default.
• W2015384236 hasConcept C2776992346 @default.
• W2015384236 hasConcept C2778820722 @default.
• W2015384236 hasConcept C2780775167 @default.
• W2015384236 hasConcept C2909375385 @default.
• W2015384236 hasConcept C529278444 @default.
• W2015384236 hasConcept C541997718 @default.
• W2015384236 hasConcept C542903549 @default.
• W2015384236 hasConcept C71924100 @default.
• W2015384236 hasConcept C84416704 @default.
• W2015384236 hasConceptScore W2015384236C118552586 @default.
• W2015384236 hasConceptScore W2015384236C126322002 @default.
• W2015384236 hasConceptScore W2015384236C142724271 @default.
• W2015384236 hasConceptScore W2015384236C159654299 @default.
• W2015384236 hasConceptScore W2015384236C16224149 @default.
• W2015384236 hasConceptScore W2015384236C178790620 @default.
• W2015384236 hasConceptScore W2015384236C185592680 @default.
• W2015384236 hasConceptScore W2015384236C185946421 @default.
• W2015384236 hasConceptScore W2015384236C203014093 @default.
• W2015384236 hasConceptScore W2015384236C2776992346 @default.
• W2015384236 hasConceptScore W2015384236C2778820722 @default.
• W2015384236 hasConceptScore W2015384236C2780775167 @default.
• W2015384236 hasConceptScore W2015384236C2909375385 @default.
• W2015384236 hasConceptScore W2015384236C529278444 @default.
• W2015384236 hasConceptScore W2015384236C541997718 @default.
• W2015384236 hasConceptScore W2015384236C542903549 @default.
• W2015384236 hasConceptScore W2015384236C71924100 @default.
• W2015384236 hasConceptScore W2015384236C84416704 @default.
• W2015384236 hasIssue "4" @default.
• W2015384236 hasLocation W20153842361 @default.
• W2015384236 hasLocation W20153842362 @default.
• W2015384236 hasOpenAccess W2015384236 @default.
• W2015384236 hasPrimaryLocation W20153842361 @default.
• W2015384236 hasRelatedWork W1968589480 @default.
• W2015384236 hasRelatedWork W2004187701 @default.
• W2015384236 hasRelatedWork W2009343987 @default.
• W2015384236 hasRelatedWork W2015384236 @default.
• W2015384236 hasRelatedWork W2015553144 @default.
• W2015384236 hasRelatedWork W2104371820 @default.
• W2015384236 hasRelatedWork W2145018314 @default.
• W2015384236 hasRelatedWork W2366917259 @default.
• W2015384236 hasRelatedWork W3031174609 @default.
• W2015384236 hasRelatedWork W3030286678 @default.
• W2015384236 hasVolume "75" @default.
• W2015384236 isParatext "false" @default.
• W2015384236 isRetracted "false" @default.

• next