Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015384494> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2015384494 endingPage "891" @default.
- W2015384494 startingPage "890" @default.
- W2015384494 abstract "Buprenorphine has been prescribed for opioid detoxification and subsequent maintenance therapy with favourable outcomes. Its high affinity for the mu receptor, higher analgesic potency than morphine, antagonistic effects at higher doses as a partial agonist, lower incidence of physical dependence, and mild withdrawal symptoms confer qualities that make it advantageous for the treatment of opioid dependence.1 Buprenorphine, marketed under the trade name Subutex, may be administered sublingually, subcutaneously, or intravenously. We describe a severe neurological effect of intravenous buprenorphine exposure that resulted in diffuse cystic leucoencephalopathy. An 18 year old man was found unconscious in his bedroom by his girlfriend. He had no past history, and no family history of neurological or metabolic diseases. He was brought to the emergency room febrile, comatose and in severe respiratory failure (pH 7.399, pO2 84 mmHg, pCO2 42 mmHg, bicarbonate 24.9 mmol/l, on 100% non-rebreathing mask). He was intubated and treated presumptively for pneumonia with intravenous imipenam and azithromycin. He did not require inotropic support. Physical examination revealed a drowsy and lethargic man, who had bilateral basal crepitations in the lungs. Apart from midrange pupils that were sluggishly reactive to light, the neurological examination was unremarkable. There was no evidence of external bruises, injuries or obvious needle track marks …" @default.
- W2015384494 created "2016-06-24" @default.
- W2015384494 creator A5007948115 @default.
- W2015384494 creator A5031223619 @default.
- W2015384494 creator A5037379114 @default.
- W2015384494 creator A5067762508 @default.
- W2015384494 date "2005-06-01" @default.
- W2015384494 modified "2023-09-26" @default.
- W2015384494 title "Diffuse cystic leucoencephalopathy after buprenorphine injection" @default.
- W2015384494 cites W119540942 @default.
- W2015384494 cites W1788790496 @default.
- W2015384494 cites W2021026424 @default.
- W2015384494 cites W2139790319 @default.
- W2015384494 cites W2414103712 @default.
- W2015384494 doi "https://doi.org/10.1136/jnnp.2004.052878" @default.
- W2015384494 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1739678" @default.
- W2015384494 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15897523" @default.
- W2015384494 hasPublicationYear "2005" @default.
- W2015384494 type Work @default.
- W2015384494 sameAs 2015384494 @default.
- W2015384494 citedByCount "9" @default.
- W2015384494 countsByYear W20153844942012 @default.
- W2015384494 countsByYear W20153844942013 @default.
- W2015384494 countsByYear W20153844942014 @default.
- W2015384494 countsByYear W20153844942022 @default.
- W2015384494 crossrefType "journal-article" @default.
- W2015384494 hasAuthorship W2015384494A5007948115 @default.
- W2015384494 hasAuthorship W2015384494A5031223619 @default.
- W2015384494 hasAuthorship W2015384494A5037379114 @default.
- W2015384494 hasAuthorship W2015384494A5067762508 @default.
- W2015384494 hasBestOaLocation W20153844941 @default.
- W2015384494 hasConcept C126322002 @default.
- W2015384494 hasConcept C170493617 @default.
- W2015384494 hasConcept C2778949969 @default.
- W2015384494 hasConcept C2781063702 @default.
- W2015384494 hasConcept C71924100 @default.
- W2015384494 hasConceptScore W2015384494C126322002 @default.
- W2015384494 hasConceptScore W2015384494C170493617 @default.
- W2015384494 hasConceptScore W2015384494C2778949969 @default.
- W2015384494 hasConceptScore W2015384494C2781063702 @default.
- W2015384494 hasConceptScore W2015384494C71924100 @default.
- W2015384494 hasIssue "6" @default.
- W2015384494 hasLocation W20153844941 @default.
- W2015384494 hasLocation W20153844942 @default.
- W2015384494 hasLocation W20153844943 @default.
- W2015384494 hasLocation W20153844944 @default.
- W2015384494 hasOpenAccess W2015384494 @default.
- W2015384494 hasPrimaryLocation W20153844941 @default.
- W2015384494 hasRelatedWork W1995515455 @default.
- W2015384494 hasRelatedWork W2080531066 @default.
- W2015384494 hasRelatedWork W2085907267 @default.
- W2015384494 hasRelatedWork W2377653959 @default.
- W2015384494 hasRelatedWork W2401961739 @default.
- W2015384494 hasRelatedWork W2748952813 @default.
- W2015384494 hasRelatedWork W2899084033 @default.
- W2015384494 hasRelatedWork W2966227943 @default.
- W2015384494 hasRelatedWork W3031052312 @default.
- W2015384494 hasRelatedWork W3032375762 @default.
- W2015384494 hasVolume "76" @default.
- W2015384494 isParatext "false" @default.
- W2015384494 isRetracted "false" @default.
- W2015384494 magId "2015384494" @default.
- W2015384494 workType "article" @default.