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• W2015392007 endingPage "296" @default.
• W2015392007 startingPage "286" @default.
• W2015392007 abstract "Objective: A review of the existing literature on ventilator-associated pneumonia in children with emphasis on problems in diagnosis. Data Sources: A systematic literature review from 1947 to 2010 using Ovid MEDLINE, PubMed, Cochrane Central Register of Controlled Trials, and ISI Web of Science using key words “ventilator associated pneumonia” and “children.” Where pediatric data were lacking, appropriate adult studies were reviewed and similarly referenced. Study Selection: Two hundred sixty-two pediatric articles were reviewed and data from 48 studies selected. Data from 61 adult articles were also included in this review. Data Extraction and Synthesis: Ventilator-associated pneumonia is the second most common nosocomial infection and the most common reason for antibiotic use in the pediatric intensive care unit. Attributable mortality is uncertain but ventilator-associated pneumonia is associated with significant morbidity and cost. Diagnosis is problematic in that clinical, radiologic, and microbiologic criteria lack sensitivity and specificity relative to autopsy histopathology and culture. Qualitative tracheal aspirate cultures are commonly used in diagnosis but lack specificity. Quantitative tracheal aspirate cultures have sensitivity (31–69%) and specificity (55–100%) comparable to bronchoalveolar lavage (11–90% and 43–100%, respectively) but concordance for the same bacterial species when compared with autopsy lung culture was better for bronchoalveolar lavage (52–90% vs. 50–76% for quantitative tracheal aspirate). Staphylococcus aureus and Pseudomonas species are the most common organisms, but microbiologic flora change over time and with antibiotic use. Initial antibiotics should offer broad-spectrum coverage but should be narrowed as clinical response and cultures dictate. Conclusions: Ventilator-associated pneumonia is an important nosocomial infection in the pediatric intensive care unit. Conclusions regarding epidemiology, treatment, and outcomes are greatly hampered by the inadequacies of current diagnostic methods. We recommend a more rigorous approach to diagnosis by using the Centers for Disease Control and Prevention algorithm. Given that ventilator-associated pneumonia is the most common reason for antibiotic use in the pediatric intensive care unit, more systematic studies are sorely needed." @default.
• W2015392007 created "2016-06-24" @default.
• W2015392007 creator A5008861589 @default.
• W2015392007 creator A5034721461 @default.
• W2015392007 creator A5035472240 @default.
• W2015392007 date "2011-05-01" @default.
• W2015392007 modified "2023-10-17" @default.
• W2015392007 title "The diagnostic dilemma of ventilator-associated pneumonia in critically ill children*" @default.
• W2015392007 cites W147164691 @default.
• W2015392007 cites W1852503640 @default.
• W2015392007 cites W1868429922 @default.
• W2015392007 cites W1942377949 @default.
• W2015392007 cites W1966375310 @default.
• W2015392007 cites W1975549643 @default.
• W2015392007 cites W1975609026 @default.
• W2015392007 cites W1976008057 @default.
• W2015392007 cites W1977342232 @default.
• W2015392007 cites W1978091434 @default.
• W2015392007 cites W1978549479 @default.
• W2015392007 cites W1983513589 @default.
• W2015392007 cites W1986298529 @default.
• W2015392007 cites W1986686413 @default.
• W2015392007 cites W1988469431 @default.
• W2015392007 cites W1989051941 @default.
• W2015392007 cites W1989381166 @default.
• W2015392007 cites W1990528277 @default.
• W2015392007 cites W1990533469 @default.
• W2015392007 cites W1993781310 @default.
• W2015392007 cites W1994512363 @default.
• W2015392007 cites W1996695146 @default.
• W2015392007 cites W1998585165 @default.
• W2015392007 cites W1999810822 @default.
• W2015392007 cites W2001280008 @default.
• W2015392007 cites W2001493005 @default.
• W2015392007 cites W2006005515 @default.
• W2015392007 cites W2007438009 @default.
• W2015392007 cites W2007605479 @default.
• W2015392007 cites W2009887163 @default.
• W2015392007 cites W2011596772 @default.
• W2015392007 cites W2011865964 @default.
• W2015392007 cites W2014019340 @default.
• W2015392007 cites W2016772536 @default.
• W2015392007 cites W2017196859 @default.
• W2015392007 cites W2023643418 @default.
• W2015392007 cites W2023982202 @default.
• W2015392007 cites W2024866548 @default.
• W2015392007 cites W2025216639 @default.
• W2015392007 cites W2025331047 @default.
• W2015392007 cites W2025380692 @default.
• W2015392007 cites W2025856919 @default.
• W2015392007 cites W2029267149 @default.
• W2015392007 cites W2033282872 @default.
• W2015392007 cites W2034336315 @default.
• W2015392007 cites W2035146109 @default.
• W2015392007 cites W2039596174 @default.
• W2015392007 cites W2042970009 @default.
• W2015392007 cites W2044623234 @default.
• W2015392007 cites W2050404478 @default.
• W2015392007 cites W2050925196 @default.
• W2015392007 cites W2051027649 @default.
• W2015392007 cites W2057588216 @default.
• W2015392007 cites W2062946079 @default.
• W2015392007 cites W2064853114 @default.
• W2015392007 cites W2065088137 @default.
• W2015392007 cites W2068939784 @default.
• W2015392007 cites W2072095871 @default.
• W2015392007 cites W2072502714 @default.
• W2015392007 cites W2076289203 @default.
• W2015392007 cites W2078367496 @default.
• W2015392007 cites W2082473381 @default.
• W2015392007 cites W2084318234 @default.
• W2015392007 cites W2085769132 @default.
• W2015392007 cites W2086098947 @default.
• W2015392007 cites W2086643362 @default.
• W2015392007 cites W2092950207 @default.
• W2015392007 cites W2095203119 @default.
• W2015392007 cites W2100154890 @default.
• W2015392007 cites W2101237743 @default.
• W2015392007 cites W2101854308 @default.
• W2015392007 cites W2102221918 @default.
• W2015392007 cites W2105210843 @default.
• W2015392007 cites W2105238960 @default.
• W2015392007 cites W2110521392 @default.
• W2015392007 cites W2111967628 @default.
• W2015392007 cites W2113396484 @default.
• W2015392007 cites W2114760693 @default.
• W2015392007 cites W2115819780 @default.
• W2015392007 cites W2116068468 @default.
• W2015392007 cites W2116108304 @default.
• W2015392007 cites W2116370033 @default.
• W2015392007 cites W2118429353 @default.
• W2015392007 cites W2128476762 @default.
• W2015392007 cites W2131338438 @default.
• W2015392007 cites W2131666000 @default.
• W2015392007 cites W2134120344 @default.
• W2015392007 cites W2139509628 @default.
• W2015392007 cites W2140270184 @default.
• W2015392007 cites W2143041376 @default.

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