FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015417818> ?p ?o ?g. }

• W2015417818 endingPage "162" @default.
• W2015417818 startingPage "158" @default.
• W2015417818 abstract "The mechanism of the antiviral activity of hypericin was characterized and compared with that of rose bengal. Both compounds inactivate enveloped (but not unenveloped) viruses upon illumination by visible light. Human immunodeficiency and vesicular stomatitis viruses were photodynamically inactivated by both dyes at nanomolar concentrations. Photodynamic inactivation of fusion (hemolysis) by vesicular stomatitis, influenza, and Sendai viruses was induced by both dyes under similar conditions (e.g., I50 = 20-50 nM for vesicular stomatitis virus), suggesting that loss of infectivity resulted from inactivation of fusion. Syncytium formation, between cells activated to express human immunodeficiency virus gp120 on their surfaces and CD4+ cells, was inhibited by illumination in the presence of 1 microM hypericin. Hypericin and rose bengal thus exert similar virucidal effects. Both presumably act by the same mechanism--namely, the inactivation of the viral fusion function by singlet oxygen produced upon illumination. The implications of this photodynamic antiviral action for the potential therapeutic usefulness of both hypericin and rose bengal are discussed." @default.
• W2015417818 created "2016-06-24" @default.
• W2015417818 creator A5014524647 @default.
• W2015417818 creator A5054053322 @default.
• W2015417818 creator A5070427178 @default.
• W2015417818 date "1993-01-01" @default.
• W2015417818 modified "2023-10-06" @default.
• W2015417818 title "Photodynamic inactivation of infectivity of human immunodeficiency virus and other enveloped viruses using hypericin and rose bengal: inhibition of fusion and syncytia formation." @default.
• W2015417818 cites W1527352542 @default.
• W2015417818 cites W1961668980 @default.
• W2015417818 cites W1965947901 @default.
• W2015417818 cites W1995541277 @default.
• W2015417818 cites W2002621703 @default.
• W2015417818 cites W2007747164 @default.
• W2015417818 cites W2013764966 @default.
• W2015417818 cites W2015059932 @default.
• W2015417818 cites W2015326137 @default.
• W2015417818 cites W2016079171 @default.
• W2015417818 cites W2018289835 @default.
• W2015417818 cites W2025542858 @default.
• W2015417818 cites W2026488427 @default.
• W2015417818 cites W2044342015 @default.
• W2015417818 cites W2057193601 @default.
• W2015417818 cites W2058940629 @default.
• W2015417818 cites W2060758897 @default.
• W2015417818 cites W2062586636 @default.
• W2015417818 cites W2070548488 @default.
• W2015417818 cites W2076951844 @default.
• W2015417818 cites W2077229311 @default.
• W2015417818 cites W2089242226 @default.
• W2015417818 cites W2090306907 @default.
• W2015417818 cites W2100837269 @default.
• W2015417818 cites W2102317992 @default.
• W2015417818 cites W2110687223 @default.
• W2015417818 cites W2137955757 @default.
• W2015417818 cites W2158858949 @default.
• W2015417818 cites W2165894555 @default.
• W2015417818 cites W2168580494 @default.
• W2015417818 doi "https://doi.org/10.1073/pnas.90.1.158" @default.
• W2015417818 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/45619" @default.
• W2015417818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7678335" @default.
• W2015417818 hasPublicationYear "1993" @default.
• W2015417818 type Work @default.
• W2015417818 sameAs 2015417818 @default.
• W2015417818 citedByCount "216" @default.
• W2015417818 countsByYear W20154178182012 @default.
• W2015417818 countsByYear W20154178182013 @default.
• W2015417818 countsByYear W20154178182014 @default.
• W2015417818 countsByYear W20154178182015 @default.
• W2015417818 countsByYear W20154178182016 @default.
• W2015417818 countsByYear W20154178182017 @default.
• W2015417818 countsByYear W20154178182018 @default.
• W2015417818 countsByYear W20154178182019 @default.
• W2015417818 countsByYear W20154178182020 @default.
• W2015417818 countsByYear W20154178182021 @default.
• W2015417818 countsByYear W20154178182022 @default.
• W2015417818 countsByYear W20154178182023 @default.
• W2015417818 crossrefType "journal-article" @default.
• W2015417818 hasAuthorship W2015417818A5014524647 @default.
• W2015417818 hasAuthorship W2015417818A5054053322 @default.
• W2015417818 hasAuthorship W2015417818A5070427178 @default.
• W2015417818 hasBestOaLocation W20154178182 @default.
• W2015417818 hasConcept C106358424 @default.
• W2015417818 hasConcept C159047783 @default.
• W2015417818 hasConcept C2522874641 @default.
• W2015417818 hasConcept C2778432610 @default.
• W2015417818 hasConcept C2779057330 @default.
• W2015417818 hasConcept C2780898351 @default.
• W2015417818 hasConcept C2910348395 @default.
• W2015417818 hasConcept C40479148 @default.
• W2015417818 hasConcept C54355233 @default.
• W2015417818 hasConcept C86803240 @default.
• W2015417818 hasConcept C89423630 @default.
• W2015417818 hasConcept C97380033 @default.
• W2015417818 hasConcept C98274493 @default.
• W2015417818 hasConceptScore W2015417818C106358424 @default.
• W2015417818 hasConceptScore W2015417818C159047783 @default.
• W2015417818 hasConceptScore W2015417818C2522874641 @default.
• W2015417818 hasConceptScore W2015417818C2778432610 @default.
• W2015417818 hasConceptScore W2015417818C2779057330 @default.
• W2015417818 hasConceptScore W2015417818C2780898351 @default.
• W2015417818 hasConceptScore W2015417818C2910348395 @default.
• W2015417818 hasConceptScore W2015417818C40479148 @default.
• W2015417818 hasConceptScore W2015417818C54355233 @default.
• W2015417818 hasConceptScore W2015417818C86803240 @default.
• W2015417818 hasConceptScore W2015417818C89423630 @default.
• W2015417818 hasConceptScore W2015417818C97380033 @default.
• W2015417818 hasConceptScore W2015417818C98274493 @default.
• W2015417818 hasIssue "1" @default.
• W2015417818 hasLocation W20154178181 @default.
• W2015417818 hasLocation W20154178182 @default.
• W2015417818 hasLocation W20154178183 @default.
• W2015417818 hasLocation W20154178184 @default.
• W2015417818 hasOpenAccess W2015417818 @default.
• W2015417818 hasPrimaryLocation W20154178181 @default.
• W2015417818 hasRelatedWork W1993085419 @default.
• W2015417818 hasRelatedWork W2015417818 @default.
• W2015417818 hasRelatedWork W2046150260 @default.

• next