FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015433973> ?p ?o ?g. }

• W2015433973 endingPage "24" @default.
• W2015433973 startingPage "19" @default.
• W2015433973 abstract "Aim: To determine the therapeutic effect of thy- mosin β4 (Tβ4) for treatment of ischemic limb disease in a mouse model. Methods: A mouse model of hindlimb ischemia was created by permanent ligation of femoral arteries and internal iliac artery. Tβ4 was dissolved in sterile saline and intramuscularly injected into the centre and periphery of ligation area in the treatment group (n = 10) starting from the surgery day until 4 weeks after surgery, while control animals received saline injection only (n = 9). All animals were sacrificed at 6 weeks after surgery and used for immunohistochemistry studies. Results: Tβ4 stimulated angiogenesis was evidenced by increased vascular density based on CD31 immunostaining, which was sig- nifycantly increased in Tβ4 group (562.5 ± 78.4/mm2) as compared with control group (371.1 ± 125.7/mm2; p 0.05) groups. Tβ4 increased Pax3/7+ skeletal muscle progenitor cell density. Pax3/7+ cell density of Tβ4 group (13.7% ± 2%) was significantly higher than that of the control group (4.3% ± 1.6%, p < 0.05). However, the numbers of central nuclei fiber and central nuclei per fiber were insignificantly increased in Tβ4 group as compared to control group. The numbers of central nuclei fiber were 8.9 ± 2.1 and 9.5 ± 1.6, and the central nuclei per fiber were 0.25 ± 0.07 and 0.48 ± 0.09 for control and Tβ4 groups, respectively. Conclusions: This preliminary study suggests that localized delivery of Tβ4 increased angiogenesis and skeletal muscle progenitor cell density in ischemic skeletal muscle, but failed to promote skeletal muscle regeneration." @default.
• W2015433973 created "2016-06-24" @default.
• W2015433973 creator A5007123441 @default.
• W2015433973 creator A5007982694 @default.
• W2015433973 creator A5037355737 @default.
• W2015433973 creator A5041502555 @default.
• W2015433973 creator A5060072253 @default.
• W2015433973 date "2012-01-01" @default.
• W2015433973 modified "2023-09-29" @default.
• W2015433973 title "Thymosin β4 promotes angiogenesis and increases muscle progenitor cell density in ischemic skeletal muscle in a mouse model of hind limb ischemia" @default.
• W2015433973 cites W1490980550 @default.
• W2015433973 cites W1968777036 @default.
• W2015433973 cites W1978126627 @default.
• W2015433973 cites W1980146498 @default.
• W2015433973 cites W1999917818 @default.
• W2015433973 cites W2004602258 @default.
• W2015433973 cites W2008747758 @default.
• W2015433973 cites W2017819318 @default.
• W2015433973 cites W2020774181 @default.
• W2015433973 cites W2023424615 @default.
• W2015433973 cites W2025259459 @default.
• W2015433973 cites W2037875382 @default.
• W2015433973 cites W2041835820 @default.
• W2015433973 cites W2071430059 @default.
• W2015433973 cites W2076480594 @default.
• W2015433973 cites W2086756183 @default.
• W2015433973 cites W2112513572 @default.
• W2015433973 cites W2120690461 @default.
• W2015433973 cites W2126496496 @default.
• W2015433973 cites W2329067941 @default.
• W2015433973 cites W43739530 @default.
• W2015433973 doi "https://doi.org/10.4236/ojrm.2012.12003" @default.
• W2015433973 hasPublicationYear "2012" @default.
• W2015433973 type Work @default.
• W2015433973 sameAs 2015433973 @default.
• W2015433973 citedByCount "0" @default.
• W2015433973 crossrefType "journal-article" @default.
• W2015433973 hasAuthorship W2015433973A5007123441 @default.
• W2015433973 hasAuthorship W2015433973A5007982694 @default.
• W2015433973 hasAuthorship W2015433973A5037355737 @default.
• W2015433973 hasAuthorship W2015433973A5041502555 @default.
• W2015433973 hasAuthorship W2015433973A5060072253 @default.
• W2015433973 hasBestOaLocation W20154339731 @default.
• W2015433973 hasConcept C105702510 @default.
• W2015433973 hasConcept C126322002 @default.
• W2015433973 hasConcept C134018914 @default.
• W2015433973 hasConcept C141071460 @default.
• W2015433973 hasConcept C179437574 @default.
• W2015433973 hasConcept C201750760 @default.
• W2015433973 hasConcept C2777397205 @default.
• W2015433973 hasConcept C2778271429 @default.
• W2015433973 hasConcept C2778939058 @default.
• W2015433973 hasConcept C2779723990 @default.
• W2015433973 hasConcept C2779959927 @default.
• W2015433973 hasConcept C2780394083 @default.
• W2015433973 hasConcept C28328180 @default.
• W2015433973 hasConcept C51738704 @default.
• W2015433973 hasConcept C541997718 @default.
• W2015433973 hasConcept C54355233 @default.
• W2015433973 hasConcept C71924100 @default.
• W2015433973 hasConcept C86803240 @default.
• W2015433973 hasConceptScore W2015433973C105702510 @default.
• W2015433973 hasConceptScore W2015433973C126322002 @default.
• W2015433973 hasConceptScore W2015433973C134018914 @default.
• W2015433973 hasConceptScore W2015433973C141071460 @default.
• W2015433973 hasConceptScore W2015433973C179437574 @default.
• W2015433973 hasConceptScore W2015433973C201750760 @default.
• W2015433973 hasConceptScore W2015433973C2777397205 @default.
• W2015433973 hasConceptScore W2015433973C2778271429 @default.
• W2015433973 hasConceptScore W2015433973C2778939058 @default.
• W2015433973 hasConceptScore W2015433973C2779723990 @default.
• W2015433973 hasConceptScore W2015433973C2779959927 @default.
• W2015433973 hasConceptScore W2015433973C2780394083 @default.
• W2015433973 hasConceptScore W2015433973C28328180 @default.
• W2015433973 hasConceptScore W2015433973C51738704 @default.
• W2015433973 hasConceptScore W2015433973C541997718 @default.
• W2015433973 hasConceptScore W2015433973C54355233 @default.
• W2015433973 hasConceptScore W2015433973C71924100 @default.
• W2015433973 hasConceptScore W2015433973C86803240 @default.
• W2015433973 hasIssue "02" @default.
• W2015433973 hasLocation W20154339731 @default.
• W2015433973 hasOpenAccess W2015433973 @default.
• W2015433973 hasPrimaryLocation W20154339731 @default.
• W2015433973 hasRelatedWork W1997809516 @default.
• W2015433973 hasRelatedWork W2004916176 @default.
• W2015433973 hasRelatedWork W2028971889 @default.
• W2015433973 hasRelatedWork W2067077551 @default.
• W2015433973 hasRelatedWork W2071721339 @default.
• W2015433973 hasRelatedWork W2084161900 @default.
• W2015433973 hasRelatedWork W2117267805 @default.
• W2015433973 hasRelatedWork W2170516402 @default.
• W2015433973 hasRelatedWork W2204912594 @default.
• W2015433973 hasRelatedWork W2347952040 @default.
• W2015433973 hasRelatedWork W2355421330 @default.
• W2015433973 hasRelatedWork W2374332001 @default.
• W2015433973 hasRelatedWork W2791459020 @default.
• W2015433973 hasRelatedWork W2897318647 @default.
• W2015433973 hasRelatedWork W2951240666 @default.

• next