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• W2015437808 abstract "In this study, eighteen monoclonal antibodies (MAbs) to recent Japanese encephalitis virus (JEV) genotype I were produced and characterized by plaque reduction neutralization test, western blot analysis, indirect immunofluorescence assay and enzyme-linked immunosorbent assay. All MAbs recognized only envelope (E) protein or conformational epitope of E and precursor membrane proteins. Two MAbs (7E5 and 3-3H8) possessed virus-neutralization activity, and their escape mutants possessed a change of glutamine to histidine at the position of 52 of E protein, suggesting that these neutralizing MAbs recognize the domain I–II hinge region of E protein. Five MAbs recognized all examined flaviviruses, and two were specific to JEV. These MAbs may be useful for differentiation and diagnosis of flaviviruses." @default.
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• W2015437808 date "2013-01-01" @default.
• W2015437808 modified "2023-10-01" @default.
• W2015437808 title "Production and Characterization of Monoclonal Antibodies to Japanese Encephalitis Virus" @default.
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• W2015437808 doi "https://doi.org/10.1292/jvms.12-0558" @default.
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