Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015440060> ?p ?o ?g. }
- W2015440060 endingPage "468" @default.
- W2015440060 startingPage "461" @default.
- W2015440060 abstract "Elevations in C-reactive protein (CRP) are associated with increased cardiovascular disease (CVD) risk, increased HIV disease progression, and death in HIV-infected patients. Use of abacavir has been reported to increase CVD risk. We assessed the effect of virologically suppressive efavirenz (EFV)-based antiretroviral therapy on high sensitivity CRP (hsCRP) levels over a 96-week period with particular attention to the effect of gender and abacavir use. Banked sera from entry and week 96 visits of AIDS Clinical Trials Group A5095 participants were assayed for hsCRP, then analyzed by gender, abacavir randomization, and for correlation with changes in fasting metabolic parameters. Analyses of hsCRP were conducted in two phases and involved a total of 145 men and 51 women. hsCRP did not differ by gender at baseline but higher levels were seen at week 96 in women (median 6 mg/liter; Q1, Q3, 1.8, 13.8) compared to men (median 1.6 mg/liter; Q1, Q3, 0.9, 4.2, p < 0.001), with an estimated shift in hsCRP by gender of 2.5 mg/liter (95% CI 1.0, 5.1). There was no difference in hsCRP levels by abacavir use. Changes in hsCRP did not correlate with changes in insulin resistance or with changes in fasting lipids. Durably virologically suppressive therapy with EFV-based regimens did not decrease hsCRP levels over a 96-week period. hsCRP levels increased significantly only in women. Randomization to abacavir had no effect on changes in hsCRP levels. Changes in hsCRP levels did not correlate with changes in fasting metabolic parameters." @default.
- W2015440060 created "2016-06-24" @default.
- W2015440060 creator A5008957693 @default.
- W2015440060 creator A5037776964 @default.
- W2015440060 creator A5038522202 @default.
- W2015440060 creator A5044125326 @default.
- W2015440060 creator A5058715015 @default.
- W2015440060 creator A5062018854 @default.
- W2015440060 creator A5072086085 @default.
- W2015440060 creator A5074342920 @default.
- W2015440060 creator A5087938521 @default.
- W2015440060 date "2011-05-01" @default.
- W2015440060 modified "2023-10-14" @default.
- W2015440060 title "Change in High-Sensitivity C-Reactive Protein Levels Following Initiation of Efavirenz-Based Antiretroviral Regimens in HIV-Infected Individuals" @default.
- W2015440060 cites W1426208733 @default.
- W2015440060 cites W1606409921 @default.
- W2015440060 cites W1970536050 @default.
- W2015440060 cites W1976077702 @default.
- W2015440060 cites W1978540833 @default.
- W2015440060 cites W1993546163 @default.
- W2015440060 cites W1997083960 @default.
- W2015440060 cites W1999215323 @default.
- W2015440060 cites W2005694005 @default.
- W2015440060 cites W2058709767 @default.
- W2015440060 cites W2061926910 @default.
- W2015440060 cites W2062117338 @default.
- W2015440060 cites W2070096329 @default.
- W2015440060 cites W2082564302 @default.
- W2015440060 cites W2084449063 @default.
- W2015440060 cites W2086893453 @default.
- W2015440060 cites W2088037915 @default.
- W2015440060 cites W2090504528 @default.
- W2015440060 cites W2093516948 @default.
- W2015440060 cites W2095218368 @default.
- W2015440060 cites W2100419955 @default.
- W2015440060 cites W2102095525 @default.
- W2015440060 cites W2118154631 @default.
- W2015440060 cites W2142179136 @default.
- W2015440060 cites W2157040546 @default.
- W2015440060 cites W2163092745 @default.
- W2015440060 cites W2167865974 @default.
- W2015440060 cites W2570113386 @default.
- W2015440060 doi "https://doi.org/10.1089/aid.2010.0154" @default.
- W2015440060 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3083724" @default.
- W2015440060 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20863238" @default.
- W2015440060 hasPublicationYear "2011" @default.
- W2015440060 type Work @default.
- W2015440060 sameAs 2015440060 @default.
- W2015440060 citedByCount "28" @default.
- W2015440060 countsByYear W20154400602012 @default.
- W2015440060 countsByYear W20154400602013 @default.
- W2015440060 countsByYear W20154400602014 @default.
- W2015440060 countsByYear W20154400602015 @default.
- W2015440060 countsByYear W20154400602016 @default.
- W2015440060 countsByYear W20154400602017 @default.
- W2015440060 countsByYear W20154400602018 @default.
- W2015440060 countsByYear W20154400602019 @default.
- W2015440060 countsByYear W20154400602020 @default.
- W2015440060 countsByYear W20154400602021 @default.
- W2015440060 countsByYear W20154400602023 @default.
- W2015440060 crossrefType "journal-article" @default.
- W2015440060 hasAuthorship W2015440060A5008957693 @default.
- W2015440060 hasAuthorship W2015440060A5037776964 @default.
- W2015440060 hasAuthorship W2015440060A5038522202 @default.
- W2015440060 hasAuthorship W2015440060A5044125326 @default.
- W2015440060 hasAuthorship W2015440060A5058715015 @default.
- W2015440060 hasAuthorship W2015440060A5062018854 @default.
- W2015440060 hasAuthorship W2015440060A5072086085 @default.
- W2015440060 hasAuthorship W2015440060A5074342920 @default.
- W2015440060 hasAuthorship W2015440060A5087938521 @default.
- W2015440060 hasBestOaLocation W20154400602 @default.
- W2015440060 hasConcept C126322002 @default.
- W2015440060 hasConcept C142462285 @default.
- W2015440060 hasConcept C168563851 @default.
- W2015440060 hasConcept C176674119 @default.
- W2015440060 hasConcept C203014093 @default.
- W2015440060 hasConcept C204243189 @default.
- W2015440060 hasConcept C2776914184 @default.
- W2015440060 hasConcept C2779465607 @default.
- W2015440060 hasConcept C2781195455 @default.
- W2015440060 hasConcept C2781432083 @default.
- W2015440060 hasConcept C2993143319 @default.
- W2015440060 hasConcept C3013748606 @default.
- W2015440060 hasConcept C71924100 @default.
- W2015440060 hasConcept C90924648 @default.
- W2015440060 hasConceptScore W2015440060C126322002 @default.
- W2015440060 hasConceptScore W2015440060C142462285 @default.
- W2015440060 hasConceptScore W2015440060C168563851 @default.
- W2015440060 hasConceptScore W2015440060C176674119 @default.
- W2015440060 hasConceptScore W2015440060C203014093 @default.
- W2015440060 hasConceptScore W2015440060C204243189 @default.
- W2015440060 hasConceptScore W2015440060C2776914184 @default.
- W2015440060 hasConceptScore W2015440060C2779465607 @default.
- W2015440060 hasConceptScore W2015440060C2781195455 @default.
- W2015440060 hasConceptScore W2015440060C2781432083 @default.
- W2015440060 hasConceptScore W2015440060C2993143319 @default.
- W2015440060 hasConceptScore W2015440060C3013748606 @default.
- W2015440060 hasConceptScore W2015440060C71924100 @default.