FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015460036> ?p ?o ?g. }

• W2015460036 endingPage "3744" @default.
• W2015460036 startingPage "3738" @default.
• W2015460036 abstract "The intracellular signal transduction controlling the proliferation of osteoblastic cells on a thin film of poorly crystalline calcium phosphate apatite crystals (PCA) was studied in vitro. The PCA thin film was prepared on polystyrene culture dishes or cover glasses using phosphate-buffered calcium ion solution, which was made oversaturated by heating an undersaturated solution prepared at low temperature. The PCA thin film was used for cell culture without additional surface treatment. Several differences were found between the cells plated on a cell culture dish and the cells cultured on the PCA surface. Entry into S-phase of the cell cycle was markedly delayed and there was a low proliferation rate of osteblast. On the PCA thin film, the cells spread in a more slender shape. Also, the formation of focal adhesions and stress fibers, examined using immunocytochemical staining, was strikingly weaker in the cells on PCA. The activation of focal adhesion kinase (FAK) was low as well. Expression of cyclins D1 and E was also lower. The Ras–Extracellular signal-regulated kinase (ERK)–MAP kinase signaling pathway was weakly activated by stimulation with serum. These results demonstrate that the low cell proliferation on the PCA surface appears to be due to insufficient activation of signaling that forces the cell cycle to progress and this may be due to weak adhesion signaling in cells on that surface." @default.
• W2015460036 created "2016-06-24" @default.
• W2015460036 creator A5054858096 @default.
• W2015460036 creator A5056954717 @default.
• W2015460036 creator A5057503980 @default.
• W2015460036 date "2006-07-01" @default.
• W2015460036 modified "2023-10-12" @default.
• W2015460036 title "The role of cell signaling defects on the proliferation of osteoblasts on the calcium phosphate apatite thin film" @default.
• W2015460036 cites W1517998622 @default.
• W2015460036 cites W1537459781 @default.
• W2015460036 cites W1577573926 @default.
• W2015460036 cites W1966260349 @default.
• W2015460036 cites W1973516089 @default.
• W2015460036 cites W1976242955 @default.
• W2015460036 cites W1976655304 @default.
• W2015460036 cites W1979379933 @default.
• W2015460036 cites W1980855212 @default.
• W2015460036 cites W1995996512 @default.
• W2015460036 cites W1996115570 @default.
• W2015460036 cites W1996752928 @default.
• W2015460036 cites W2003852585 @default.
• W2015460036 cites W2004160140 @default.
• W2015460036 cites W2009089387 @default.
• W2015460036 cites W2029080338 @default.
• W2015460036 cites W2029720743 @default.
• W2015460036 cites W2031626005 @default.
• W2015460036 cites W2043556491 @default.
• W2015460036 cites W2058096164 @default.
• W2015460036 cites W2063753069 @default.
• W2015460036 cites W2067719770 @default.
• W2015460036 cites W2078636606 @default.
• W2015460036 cites W2079496133 @default.
• W2015460036 cites W2085129546 @default.
• W2015460036 cites W2085516239 @default.
• W2015460036 cites W2090394742 @default.
• W2015460036 cites W2093208114 @default.
• W2015460036 cites W2094597207 @default.
• W2015460036 cites W2116500217 @default.
• W2015460036 cites W2128884401 @default.
• W2015460036 cites W2139235346 @default.
• W2015460036 cites W2143201493 @default.
• W2015460036 cites W2146986405 @default.
• W2015460036 cites W2154083290 @default.
• W2015460036 cites W2159528039 @default.
• W2015460036 cites W2317270770 @default.
• W2015460036 cites W2404564992 @default.
• W2015460036 doi "https://doi.org/10.1016/j.biomaterials.2006.02.032" @default.
• W2015460036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16530826" @default.
• W2015460036 hasPublicationYear "2006" @default.
• W2015460036 type Work @default.
• W2015460036 sameAs 2015460036 @default.
• W2015460036 citedByCount "27" @default.
• W2015460036 countsByYear W20154600362012 @default.
• W2015460036 countsByYear W20154600362013 @default.
• W2015460036 countsByYear W20154600362014 @default.
• W2015460036 countsByYear W20154600362015 @default.
• W2015460036 countsByYear W20154600362016 @default.
• W2015460036 countsByYear W20154600362017 @default.
• W2015460036 countsByYear W20154600362020 @default.
• W2015460036 countsByYear W20154600362022 @default.
• W2015460036 crossrefType "journal-article" @default.
• W2015460036 hasAuthorship W2015460036A5054858096 @default.
• W2015460036 hasAuthorship W2015460036A5056954717 @default.
• W2015460036 hasAuthorship W2015460036A5057503980 @default.
• W2015460036 hasConcept C12554922 @default.
• W2015460036 hasConcept C151166631 @default.
• W2015460036 hasConcept C159985019 @default.
• W2015460036 hasConcept C184235292 @default.
• W2015460036 hasConcept C191897082 @default.
• W2015460036 hasConcept C192562407 @default.
• W2015460036 hasConcept C28406088 @default.
• W2015460036 hasConcept C519063684 @default.
• W2015460036 hasConcept C55493867 @default.
• W2015460036 hasConcept C57074206 @default.
• W2015460036 hasConcept C62112901 @default.
• W2015460036 hasConcept C62478195 @default.
• W2015460036 hasConcept C84416704 @default.
• W2015460036 hasConcept C85789140 @default.
• W2015460036 hasConcept C86803240 @default.
• W2015460036 hasConcept C95444343 @default.
• W2015460036 hasConceptScore W2015460036C12554922 @default.
• W2015460036 hasConceptScore W2015460036C151166631 @default.
• W2015460036 hasConceptScore W2015460036C159985019 @default.
• W2015460036 hasConceptScore W2015460036C184235292 @default.
• W2015460036 hasConceptScore W2015460036C191897082 @default.
• W2015460036 hasConceptScore W2015460036C192562407 @default.
• W2015460036 hasConceptScore W2015460036C28406088 @default.
• W2015460036 hasConceptScore W2015460036C519063684 @default.
• W2015460036 hasConceptScore W2015460036C55493867 @default.
• W2015460036 hasConceptScore W2015460036C57074206 @default.
• W2015460036 hasConceptScore W2015460036C62112901 @default.
• W2015460036 hasConceptScore W2015460036C62478195 @default.
• W2015460036 hasConceptScore W2015460036C84416704 @default.
• W2015460036 hasConceptScore W2015460036C85789140 @default.
• W2015460036 hasConceptScore W2015460036C86803240 @default.
• W2015460036 hasConceptScore W2015460036C95444343 @default.
• W2015460036 hasIssue "20" @default.
• W2015460036 hasLocation W20154600361 @default.

• next