Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015473806> ?p ?o ?g. }
- W2015473806 endingPage "140" @default.
- W2015473806 startingPage "133" @default.
- W2015473806 abstract "Small-cell lung carcinomas (SCLC) represent less than 20% of all lung cancers. As it is an aggressive tumour, on account of its high and early risk of dissemination, only a third of patients have limited-stage disease at diagnosis. For these patients, the current state-of-the-art treatment involves cisplatin-etoposide chemotherapy combined with chest radiotherapy. Because of the high risk of brain metastases, prophylactic cranial irradiation (PCI) is indicated in good responders and should be part of the standard management of these patients on the basis of a PCI meta-analysis showing a 5% increase in survival at 3 years. The 5-year survival rate reaches 25% in the best series. This progress is subsequent to a better combination of polychemotherapy and both thoracic and cerebral irradiation. In extensive disease, radiotherapy has also a place in the management of SCLC: PCI reduces the risk of brain metastases and significantly improves overall survival, so that cisplatin (or carboplatin)-etoposide followed by PCI in responding patients has become the standard treatment. Many issues are subject for further clinical research concerning timing, volume and schedule of thoracic radiotherapy to be used in combination with chemotherapy regimen. Progress in thoracic radiotherapy can only be achieved by including patients in prospective studies." @default.
- W2015473806 created "2016-06-24" @default.
- W2015473806 creator A5004321308 @default.
- W2015473806 creator A5040874354 @default.
- W2015473806 date "2010-08-01" @default.
- W2015473806 modified "2023-10-14" @default.
- W2015473806 title "Radiotherapy in small-cell lung cancer: Where should it go?" @default.
- W2015473806 cites W1495781375 @default.
- W2015473806 cites W1546955416 @default.
- W2015473806 cites W1827473618 @default.
- W2015473806 cites W1839070320 @default.
- W2015473806 cites W1885320430 @default.
- W2015473806 cites W1895951835 @default.
- W2015473806 cites W1898381946 @default.
- W2015473806 cites W1905406155 @default.
- W2015473806 cites W1910638072 @default.
- W2015473806 cites W1918962731 @default.
- W2015473806 cites W1920090590 @default.
- W2015473806 cites W1923792259 @default.
- W2015473806 cites W1938763320 @default.
- W2015473806 cites W1951176292 @default.
- W2015473806 cites W1961685780 @default.
- W2015473806 cites W1969034942 @default.
- W2015473806 cites W1971660087 @default.
- W2015473806 cites W1973510243 @default.
- W2015473806 cites W1977531669 @default.
- W2015473806 cites W1989315499 @default.
- W2015473806 cites W1992291788 @default.
- W2015473806 cites W2001739398 @default.
- W2015473806 cites W2003230498 @default.
- W2015473806 cites W2011868684 @default.
- W2015473806 cites W2013136834 @default.
- W2015473806 cites W2018754160 @default.
- W2015473806 cites W2021987821 @default.
- W2015473806 cites W2026867617 @default.
- W2015473806 cites W2049247217 @default.
- W2015473806 cites W2054450785 @default.
- W2015473806 cites W2058625982 @default.
- W2015473806 cites W2059808161 @default.
- W2015473806 cites W2061344244 @default.
- W2015473806 cites W2067719172 @default.
- W2015473806 cites W2073153700 @default.
- W2015473806 cites W2075954920 @default.
- W2015473806 cites W2077233371 @default.
- W2015473806 cites W2080392924 @default.
- W2015473806 cites W2100410313 @default.
- W2015473806 cites W2110391705 @default.
- W2015473806 cites W2112109633 @default.
- W2015473806 cites W2124353451 @default.
- W2015473806 cites W2125430981 @default.
- W2015473806 cites W2127093828 @default.
- W2015473806 cites W2127132002 @default.
- W2015473806 cites W2127947104 @default.
- W2015473806 cites W2131219536 @default.
- W2015473806 cites W2136570034 @default.
- W2015473806 cites W2137253370 @default.
- W2015473806 cites W2138683149 @default.
- W2015473806 cites W2143124651 @default.
- W2015473806 cites W2148554106 @default.
- W2015473806 cites W2150713507 @default.
- W2015473806 cites W2150878803 @default.
- W2015473806 cites W2154612716 @default.
- W2015473806 cites W2160012348 @default.
- W2015473806 cites W2162472616 @default.
- W2015473806 cites W2164306710 @default.
- W2015473806 cites W2180591941 @default.
- W2015473806 cites W2216166526 @default.
- W2015473806 cites W2217024456 @default.
- W2015473806 cites W2263690797 @default.
- W2015473806 cites W2323020638 @default.
- W2015473806 cites W2339444986 @default.
- W2015473806 cites W2340438890 @default.
- W2015473806 cites W2340678921 @default.
- W2015473806 cites W2341745217 @default.
- W2015473806 doi "https://doi.org/10.1016/j.lungcan.2010.04.019" @default.
- W2015473806 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20605651" @default.
- W2015473806 hasPublicationYear "2010" @default.
- W2015473806 type Work @default.
- W2015473806 sameAs 2015473806 @default.
- W2015473806 citedByCount "34" @default.
- W2015473806 countsByYear W20154738062012 @default.
- W2015473806 countsByYear W20154738062013 @default.
- W2015473806 countsByYear W20154738062014 @default.
- W2015473806 countsByYear W20154738062015 @default.
- W2015473806 countsByYear W20154738062016 @default.
- W2015473806 countsByYear W20154738062017 @default.
- W2015473806 countsByYear W20154738062018 @default.
- W2015473806 countsByYear W20154738062019 @default.
- W2015473806 countsByYear W20154738062020 @default.
- W2015473806 countsByYear W20154738062022 @default.
- W2015473806 countsByYear W20154738062023 @default.
- W2015473806 crossrefType "journal-article" @default.
- W2015473806 hasAuthorship W2015473806A5004321308 @default.
- W2015473806 hasAuthorship W2015473806A5040874354 @default.
- W2015473806 hasConcept C126322002 @default.
- W2015473806 hasConcept C126838900 @default.
- W2015473806 hasConcept C141071460 @default.
- W2015473806 hasConcept C143998085 @default.