FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015477907> ?p ?o ?g. }

• W2015477907 endingPage "127" @default.
• W2015477907 startingPage "113" @default.
• W2015477907 abstract "The Drosophila gene trithorax (trx) is required for the normal expression of a number of the homeotic genes in the bithorax complex (BX-C) and the Antennapedia complex (ANT-C). Flies homozygous for trx mutations exhibit segmental identity transformations similar to those caused by loss-of-function mutations in the homeotic genes Sex combs reduced (Scr), Ultrabithorax (Ubx), abdominal-A (abd-A), and Abdominal-B (Abd-B). We present a molecular characterization of the trx locus and show that it is necessary for normal levels of Antennapedia (Antp), Ubx, and abd-A protein accumulation. Interestingly, the loss of trx function differentially affects the expression these proteins; Ubx protein levels are greatly reduced, aba-A protein levels are reduced to a lesser extent, and Antp protein levels are only slightly reduced. P-element mediated transformation using 34 kb of genomic DNA containing the 25 kb trx transcription unit identifies all sequences necessary for normal trx function and limits the 5′ and 3′ flanking sequences that could be used in a regulatory capacity to relatively small regions. The primary transcription unit is differentially spliced to produce two large transcripts of 12 and 15 kb that have different developmental profiles." @default.
• W2015477907 created "2016-06-24" @default.
• W2015477907 creator A5024987865 @default.
• W2015477907 creator A5061845688 @default.
• W2015477907 date "1991-09-01" @default.
• W2015477907 modified "2023-10-16" @default.
• W2015477907 title "Molecular characterization of the trithorax gene, a positive regulator of homeotic gene expression in Drosophila" @default.
• W2015477907 cites W137437809 @default.
• W2015477907 cites W1565800544 @default.
• W2015477907 cites W1763671285 @default.
• W2015477907 cites W1767110377 @default.
• W2015477907 cites W1815472980 @default.
• W2015477907 cites W1824082494 @default.
• W2015477907 cites W1824574332 @default.
• W2015477907 cites W1836693088 @default.
• W2015477907 cites W1877731130 @default.
• W2015477907 cites W1881652542 @default.
• W2015477907 cites W1891332773 @default.
• W2015477907 cites W1927398280 @default.
• W2015477907 cites W1964455793 @default.
• W2015477907 cites W1965117722 @default.
• W2015477907 cites W1967734956 @default.
• W2015477907 cites W1968885294 @default.
• W2015477907 cites W1970087350 @default.
• W2015477907 cites W1974426489 @default.
• W2015477907 cites W1977024243 @default.
• W2015477907 cites W1978637982 @default.
• W2015477907 cites W1981231195 @default.
• W2015477907 cites W1984173520 @default.
• W2015477907 cites W1987718027 @default.
• W2015477907 cites W1995112067 @default.
• W2015477907 cites W2000871658 @default.
• W2015477907 cites W2002282158 @default.
• W2015477907 cites W2003056363 @default.
• W2015477907 cites W2006788765 @default.
• W2015477907 cites W2011192730 @default.
• W2015477907 cites W2015100891 @default.
• W2015477907 cites W2015937855 @default.
• W2015477907 cites W2016089890 @default.
• W2015477907 cites W2021550045 @default.
• W2015477907 cites W2021839340 @default.
• W2015477907 cites W2024571097 @default.
• W2015477907 cites W2025303794 @default.
• W2015477907 cites W2028815756 @default.
• W2015477907 cites W2032499371 @default.
• W2015477907 cites W2034019749 @default.
• W2015477907 cites W2037128257 @default.
• W2015477907 cites W2049838999 @default.
• W2015477907 cites W2053352747 @default.
• W2015477907 cites W2054270039 @default.
• W2015477907 cites W2054852170 @default.
• W2015477907 cites W2055013769 @default.
• W2015477907 cites W2057781992 @default.
• W2015477907 cites W2063450941 @default.
• W2015477907 cites W2064251573 @default.
• W2015477907 cites W2075920111 @default.
• W2015477907 cites W2077995348 @default.
• W2015477907 cites W2078950449 @default.
• W2015477907 cites W2079651862 @default.
• W2015477907 cites W2084767452 @default.
• W2015477907 cites W2085171463 @default.
• W2015477907 cites W2095520922 @default.
• W2015477907 cites W2103586046 @default.
• W2015477907 cites W2111341106 @default.
• W2015477907 cites W2123527968 @default.
• W2015477907 cites W2128802089 @default.
• W2015477907 cites W2143574488 @default.
• W2015477907 cites W2163527903 @default.
• W2015477907 cites W2176692887 @default.
• W2015477907 cites W2219060160 @default.
• W2015477907 cites W2224929038 @default.
• W2015477907 cites W2237290340 @default.
• W2015477907 cites W2311462073 @default.
• W2015477907 cites W2340480656 @default.
• W2015477907 cites W2412928540 @default.
• W2015477907 cites W262926024 @default.
• W2015477907 cites W2887703191 @default.
• W2015477907 cites W2941484744 @default.
• W2015477907 cites W33805216 @default.
• W2015477907 cites W349216648 @default.
• W2015477907 cites W35374334 @default.
• W2015477907 cites W4249717802 @default.
• W2015477907 cites W4300448772 @default.
• W2015477907 doi "https://doi.org/10.1016/0925-4773(91)90062-b" @default.
• W2015477907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1684714" @default.
• W2015477907 hasPublicationYear "1991" @default.
• W2015477907 type Work @default.
• W2015477907 sameAs 2015477907 @default.
• W2015477907 citedByCount "80" @default.
• W2015477907 countsByYear W20154779072012 @default.
• W2015477907 countsByYear W20154779072013 @default.
• W2015477907 countsByYear W20154779072014 @default.
• W2015477907 countsByYear W20154779072015 @default.
• W2015477907 countsByYear W20154779072016 @default.
• W2015477907 countsByYear W20154779072017 @default.
• W2015477907 countsByYear W20154779072018 @default.
• W2015477907 countsByYear W20154779072019 @default.
• W2015477907 countsByYear W20154779072020 @default.

• next