FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015486587> ?p ?o ?g. }

• W2015486587 endingPage "931" @default.
• W2015486587 startingPage "924" @default.
• W2015486587 abstract "Investigating potential central nervous system (CNS) activities of Crataegus monogyna Jacq. (Rosaceae), hawthorn, fruit extracts.Evaluating CNS effects and analgesic activities of hawthorn fruit extracts based on the traditional uses of the plant for neurosedative and pain killer actions.Effects of hawthorn pulp (HPE) and seed extracts (HSE) at the dose range of 1-1000 mg/kg were examined on anxiety level, spontaneous locomotor activity, motor coordination, and nociceptive perception of mice. Morphine was used as a reference drug.HPE (100-1000 mg/kg) and HSE (10-1000 mg/kg) significantly decreased not only the exploratory behaviors in hole-board experiments, but also the spontaneous locomotor activities in activity cage tests. The same doses of extracts were found to be ineffective in Rota-Rod tests of mice. In tail-clip, hot-plate, and acetic acid-induced writhing tests, quite potent and dose-dependent analgesic activities were seen at 100-1000 mg/kg doses of HPE and 10-1000 mg/kg doses of HSE. Analgesic effects observed in all analgesia tests were antagonized by naloxone.Significant and dose-dependent decreases in spontaneous locomotor activities and exploratory behaviors of animals suggested CNS depressant activities of both extracts. Complete naloxone antagonism in all applied analgesia tests indicated opioid-related analgesic activities of both extracts.These findings seem to support the traditional use of this plant to treat stress, nervousness, sleep disorders, and pain control." @default.
• W2015486587 created "2016-06-24" @default.
• W2015486587 creator A5012641576 @default.
• W2015486587 creator A5017325490 @default.
• W2015486587 creator A5020313406 @default.
• W2015486587 creator A5031147005 @default.
• W2015486587 date "2010-08-01" @default.
• W2015486587 modified "2023-10-14" @default.
• W2015486587 title "Effects of hawthorn seed and pulp extracts on the central nervous system" @default.
• W2015486587 cites W1596781081 @default.
• W2015486587 cites W1950780876 @default.
• W2015486587 cites W1966861273 @default.
• W2015486587 cites W1967132326 @default.
• W2015486587 cites W1971267207 @default.
• W2015486587 cites W1979847131 @default.
• W2015486587 cites W1986992379 @default.
• W2015486587 cites W1991645294 @default.
• W2015486587 cites W1992281320 @default.
• W2015486587 cites W1995984571 @default.
• W2015486587 cites W1998618564 @default.
• W2015486587 cites W1999426514 @default.
• W2015486587 cites W2000974099 @default.
• W2015486587 cites W2001966356 @default.
• W2015486587 cites W2006431114 @default.
• W2015486587 cites W2013736201 @default.
• W2015486587 cites W2020016460 @default.
• W2015486587 cites W2020934245 @default.
• W2015486587 cites W2023661403 @default.
• W2015486587 cites W2026096259 @default.
• W2015486587 cites W2026861169 @default.
• W2015486587 cites W2027389756 @default.
• W2015486587 cites W2029657598 @default.
• W2015486587 cites W2037973712 @default.
• W2015486587 cites W2047139461 @default.
• W2015486587 cites W2050513886 @default.
• W2015486587 cites W2058535118 @default.
• W2015486587 cites W2061657649 @default.
• W2015486587 cites W2061835446 @default.
• W2015486587 cites W2064039725 @default.
• W2015486587 cites W2067749042 @default.
• W2015486587 cites W2068227193 @default.
• W2015486587 cites W2078200910 @default.
• W2015486587 cites W2104842126 @default.
• W2015486587 cites W2125299541 @default.
• W2015486587 cites W2147235866 @default.
• W2015486587 cites W2153791073 @default.
• W2015486587 cites W2473886513 @default.
• W2015486587 cites W4241594987 @default.
• W2015486587 cites W4249898105 @default.
• W2015486587 doi "https://doi.org/10.3109/13880200903305500" @default.
• W2015486587 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20673180" @default.
• W2015486587 hasPublicationYear "2010" @default.
• W2015486587 type Work @default.
• W2015486587 sameAs 2015486587 @default.
• W2015486587 citedByCount "34" @default.
• W2015486587 countsByYear W20154865872012 @default.
• W2015486587 countsByYear W20154865872013 @default.
• W2015486587 countsByYear W20154865872014 @default.
• W2015486587 countsByYear W20154865872015 @default.
• W2015486587 countsByYear W20154865872016 @default.
• W2015486587 countsByYear W20154865872017 @default.
• W2015486587 countsByYear W20154865872019 @default.
• W2015486587 countsByYear W20154865872020 @default.
• W2015486587 countsByYear W20154865872021 @default.
• W2015486587 countsByYear W20154865872022 @default.
• W2015486587 countsByYear W20154865872023 @default.
• W2015486587 crossrefType "journal-article" @default.
• W2015486587 hasAuthorship W2015486587A5012641576 @default.
• W2015486587 hasAuthorship W2015486587A5017325490 @default.
• W2015486587 hasAuthorship W2015486587A5020313406 @default.
• W2015486587 hasAuthorship W2015486587A5031147005 @default.
• W2015486587 hasBestOaLocation W20154865871 @default.
• W2015486587 hasConcept C126322002 @default.
• W2015486587 hasConcept C170493617 @default.
• W2015486587 hasConcept C2777389121 @default.
• W2015486587 hasConcept C2778750930 @default.
• W2015486587 hasConcept C2780820201 @default.
• W2015486587 hasConcept C2781063702 @default.
• W2015486587 hasConcept C2909214880 @default.
• W2015486587 hasConcept C29730261 @default.
• W2015486587 hasConcept C42219234 @default.
• W2015486587 hasConcept C529278444 @default.
• W2015486587 hasConcept C71924100 @default.
• W2015486587 hasConcept C98274493 @default.
• W2015486587 hasConceptScore W2015486587C126322002 @default.
• W2015486587 hasConceptScore W2015486587C170493617 @default.
• W2015486587 hasConceptScore W2015486587C2777389121 @default.
• W2015486587 hasConceptScore W2015486587C2778750930 @default.
• W2015486587 hasConceptScore W2015486587C2780820201 @default.
• W2015486587 hasConceptScore W2015486587C2781063702 @default.
• W2015486587 hasConceptScore W2015486587C2909214880 @default.
• W2015486587 hasConceptScore W2015486587C29730261 @default.
• W2015486587 hasConceptScore W2015486587C42219234 @default.
• W2015486587 hasConceptScore W2015486587C529278444 @default.
• W2015486587 hasConceptScore W2015486587C71924100 @default.
• W2015486587 hasConceptScore W2015486587C98274493 @default.
• W2015486587 hasIssue "8" @default.
• W2015486587 hasLocation W20154865871 @default.

• next