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- W2015497657 abstract "We have isolated a cDNA that contains the complete coding sequence of a 3.0 × 103 base human fibroblast mRNA together with a large part of its 3′ untranslated sequence. The deduced protein sequence is very similar if not identical to the sequence of horse platelet tropomyosin, a 247 amino acid protein. In vitro translation of an SP6 transcript of this cDNA reveals that the protein product of the 3.0 × 103 base mRNA is TM30pl, one of the five proteins in human fibroblasts that have been shown to possess the physical and chemical characteristics of tropomyosin. This mRNA is encoded by a gene family that consists of a functional gene and multiple RNA-copy pseudogenes. This family of sequences is distinct from the gene family encoding TM30nm, a cytoskeletal tropomyosin very similar in electrophoretic mobility to TM30pl, but which shows significant differences in primary structure." @default.
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- W2015497657 date "1987-03-01" @default.
- W2015497657 modified "2023-09-26" @default.
- W2015497657 title "Characterization of a cDNA defining a gene family encoding TM30pl, a human fibroblast tropomyosin" @default.
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- W2015497657 doi "https://doi.org/10.1016/0022-2836(87)90710-8" @default.
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