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- W2015509640 abstract "The corrosion rates of a titanium alloy, a stainless steel and a cobalt-chromium alloy have been studied over a 9-day incubation period in culture medium supplemented with foetal calf serum, with and without the presence of human osteoblasts. The release of titanium, chromium and cobalt showed a slight increase (20–40%) in the presence of osteoblasts. Cr was taken up to a greater extent (45%) by the cells. At day 9 titanium alloy was cytocompatible, whereas in contact with stainless steel and cobalt-chromium alloy osteoblast alkaline phosphatase activity was reduced, although cell growth was unaffected. This real-time testing procedure seems a good model for evaluating simultaneously in vitro the biodegradation and the biocompatibility of an orthopaedic alloy." @default.
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- W2015509640 title "In vitro study of biomaterial biodegradation using human cell cultures" @default.
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- W2015509640 doi "https://doi.org/10.1016/0267-6605(94)90059-0" @default.
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