Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015514181> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2015514181 endingPage "389" @default.
- W2015514181 startingPage "381" @default.
- W2015514181 abstract "C3H/HeJ mice received B10.BR skin grafts following portal or lateral tail vein infusion of irradiated B10.BR spleen cells. Thereafter mice were injected with anti‐αβ or anti‐γδ T‐cell receptor (TCR) monoclonal antibody (mAb). Anti‐γδ TCR mAb abolished the increased graft survival afforded by portal venous (p.v.) immunization, and reversed the bias towards expression of mRNA for type‐2 cytokines [interleukin‐4 (IL‐4), IL‐10] seen in lymphoid tissue of p.v.‐immunized mice. When γδ TCR + and αβ TCR + cells were isolated from the intestinal epithelial compartment (IEL), liver or Peyer's Patch (PP) of p.v.‐immunized mice, the γδ TCR + cells were found to be enriched in cells producing type‐2 cytokines on rechallenge with irradiated B10.BR cells in vitro . γδ TCR + cells from p.v.‐immunized mice were further expanded in vitro with anti‐CD3 and cytokines (combined IL‐2 and IL‐4). Following expansion these cells were capable of adoptively transferring increased B10.BR skin graft survival to naive mice, and continued to show a bias in type‐2 cytokine synthesis after allostimulation in vitro . When γδ TCR chain expression was assessed in cells taken from p.v.‐immunized mice, or in cells expanded in culture, our data suggest that p.v. immunization leads to oligoclonal, not polyclonal, expansion of those γδ TCR + cells involved in inhibition of graft rejection." @default.
- W2015514181 created "2016-06-24" @default.
- W2015514181 creator A5013168738 @default.
- W2015514181 creator A5051922091 @default.
- W2015514181 creator A5069562108 @default.
- W2015514181 creator A5091854795 @default.
- W2015514181 date "1996-03-01" @default.
- W2015514181 modified "2023-09-27" @default.
- W2015514181 title "A subset of γδ T‐cell receptor‐positive cells produce T‐helper type‐2 cytokines and regulate mouse skin graft rejection following portal venous pretransplant preimmunization" @default.
- W2015514181 cites W1492322782 @default.
- W2015514181 cites W1530997192 @default.
- W2015514181 cites W1544490832 @default.
- W2015514181 cites W1550737410 @default.
- W2015514181 cites W1581723753 @default.
- W2015514181 cites W1625191949 @default.
- W2015514181 cites W1665855995 @default.
- W2015514181 cites W1973556048 @default.
- W2015514181 cites W1985915533 @default.
- W2015514181 cites W2008238441 @default.
- W2015514181 cites W2009331647 @default.
- W2015514181 cites W2043462667 @default.
- W2015514181 cites W2044010336 @default.
- W2015514181 cites W2053238874 @default.
- W2015514181 cites W2087993789 @default.
- W2015514181 cites W2088763689 @default.
- W2015514181 cites W2104106789 @default.
- W2015514181 cites W2128248272 @default.
- W2015514181 cites W2154503489 @default.
- W2015514181 cites W2395061533 @default.
- W2015514181 cites W2399661242 @default.
- W2015514181 cites W1482269072 @default.
- W2015514181 doi "https://doi.org/10.1046/j.1365-2567.1996.481554.x" @default.
- W2015514181 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1384105" @default.
- W2015514181 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8778022" @default.
- W2015514181 hasPublicationYear "1996" @default.
- W2015514181 type Work @default.
- W2015514181 sameAs 2015514181 @default.
- W2015514181 citedByCount "57" @default.
- W2015514181 countsByYear W20155141812012 @default.
- W2015514181 countsByYear W20155141812014 @default.
- W2015514181 countsByYear W20155141812015 @default.
- W2015514181 countsByYear W20155141812016 @default.
- W2015514181 countsByYear W20155141812018 @default.
- W2015514181 countsByYear W20155141812019 @default.
- W2015514181 countsByYear W20155141812020 @default.
- W2015514181 countsByYear W20155141812021 @default.
- W2015514181 crossrefType "journal-article" @default.
- W2015514181 hasAuthorship W2015514181A5013168738 @default.
- W2015514181 hasAuthorship W2015514181A5051922091 @default.
- W2015514181 hasAuthorship W2015514181A5069562108 @default.
- W2015514181 hasAuthorship W2015514181A5091854795 @default.
- W2015514181 hasBestOaLocation W20155141812 @default.
- W2015514181 hasConcept C114684123 @default.
- W2015514181 hasConcept C129374314 @default.
- W2015514181 hasConcept C147483822 @default.
- W2015514181 hasConcept C153911025 @default.
- W2015514181 hasConcept C167672396 @default.
- W2015514181 hasConcept C19317047 @default.
- W2015514181 hasConcept C203014093 @default.
- W2015514181 hasConcept C2776090121 @default.
- W2015514181 hasConcept C2778690821 @default.
- W2015514181 hasConcept C2780931953 @default.
- W2015514181 hasConcept C86803240 @default.
- W2015514181 hasConcept C8891405 @default.
- W2015514181 hasConceptScore W2015514181C114684123 @default.
- W2015514181 hasConceptScore W2015514181C129374314 @default.
- W2015514181 hasConceptScore W2015514181C147483822 @default.
- W2015514181 hasConceptScore W2015514181C153911025 @default.
- W2015514181 hasConceptScore W2015514181C167672396 @default.
- W2015514181 hasConceptScore W2015514181C19317047 @default.
- W2015514181 hasConceptScore W2015514181C203014093 @default.
- W2015514181 hasConceptScore W2015514181C2776090121 @default.
- W2015514181 hasConceptScore W2015514181C2778690821 @default.
- W2015514181 hasConceptScore W2015514181C2780931953 @default.
- W2015514181 hasConceptScore W2015514181C86803240 @default.
- W2015514181 hasConceptScore W2015514181C8891405 @default.
- W2015514181 hasIssue "3" @default.
- W2015514181 hasLocation W20155141811 @default.
- W2015514181 hasLocation W20155141812 @default.
- W2015514181 hasLocation W20155141813 @default.
- W2015514181 hasOpenAccess W2015514181 @default.
- W2015514181 hasPrimaryLocation W20155141811 @default.
- W2015514181 hasRelatedWork W1518741832 @default.
- W2015514181 hasRelatedWork W1563891191 @default.
- W2015514181 hasRelatedWork W1578777653 @default.
- W2015514181 hasRelatedWork W2025159433 @default.
- W2015514181 hasRelatedWork W2042173550 @default.
- W2015514181 hasRelatedWork W2066661529 @default.
- W2015514181 hasRelatedWork W2093146731 @default.
- W2015514181 hasRelatedWork W2551151960 @default.
- W2015514181 hasRelatedWork W4313333775 @default.
- W2015514181 hasRelatedWork W631190123 @default.
- W2015514181 hasVolume "87" @default.
- W2015514181 isParatext "false" @default.
- W2015514181 isRetracted "false" @default.
- W2015514181 magId "2015514181" @default.
- W2015514181 workType "article" @default.