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- W2015514301 abstract "Alterations in regional cerebral blood-flow, a s determined by single-photon emission computed tomography (SPECT) using technetium [*Tc] hexamethyl propylenamine oxime, were studied in two children presenting with alternating hemiplegia of childhood. Both experienced hemiplegic episodes several times per month, despite marked improvement on flunarizine therapy. SPECT images of both patients revealed focal areas of decreased uptake of the radiotracer, representing impaired regional cerebral blood-flow during, as well as between, seizures. The interictal finding of localized areas of reduced tracer uptake suggest that long-lasting hypoperfusion could be the patho-physiological, mechanism by which the slowly resolving hemiplegia, and ultimately the permanent multifocal neurological deficits, are produced." @default.
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- W2015514301 date "2008-11-12" @default.
- W2015514301 modified "2023-09-27" @default.
- W2015514301 title "Single-photon Emission Computed Tomography Investigations of Alternating Hemiplegia of Childhood" @default.
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- W2015514301 doi "https://doi.org/10.1111/j.1469-8749.1993.tb11647.x" @default.
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