Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015514443> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2015514443 endingPage "656" @default.
- W2015514443 startingPage "651" @default.
- W2015514443 abstract "Background The study was designed to determine and compare the median effective doses (MEDs) of intrathecal ropivacaine with levobupivacaine for labor analgesia. Methods In this double-blind study, 100 parturients in early labor were randomized to receive either intrathecal ropivacaine or levobupivacaine. For each drug, the patients were assigned to receive one of the five doses studied, namely 1, 1.5, 2, 2.5, or 3 mg. Effective analgesia was defined as a pain score (0-100 visual analog scale) of less than 10 within 15 min of injection, lasting for 45 min or more after the induction of analgesia. MEDs were derived from probit analysis. The duration of analgesia rendered by the two drugs at 2.5 and 3 mg was also compared. Results The MED for levobupivacaine was 1.07 mg (95% confidence interval, 0.88-1.25 mg), and the MED for ropivacaine was 1.40 mg (95% confidence interval, 1.20-1.61 mg). Levobupivacaine was found to be 1.31 (95% confidence interval, 1.04-2.01) times more potent than ropivacaine. At doses of 2.5 mg or greater, there was no significant difference in duration of analgesia between levobupivacaine (median, 63.5 min; range, 46-123 min) and ropivacaine (median, 59.0 min; range, 47-93 min; P = 0.18). We detected no difference in the incidence of hypotension, nausea and vomiting, motor block, or abnormal fetal heart tracing between the two drugs. Conclusions The MED of intrathecal ropivacaine for labor analgesia was significantly greater than levobupivacaine experimentally, but this significance was reduced when the comparison was based on molar potency. There was no difference in the duration of analgesia or adverse effects between the two drugs at higher doses (2.5 mg or greater)." @default.
- W2015514443 created "2016-06-24" @default.
- W2015514443 creator A5010573384 @default.
- W2015514443 creator A5041649938 @default.
- W2015514443 creator A5046179971 @default.
- W2015514443 creator A5066276345 @default.
- W2015514443 date "2005-03-01" @default.
- W2015514443 modified "2023-09-26" @default.
- W2015514443 title "A Comparison of Median Effective Doses of Intrathecal Levobupivacaine and Ropivacaine for Labor Analgesia" @default.
- W2015514443 cites W1546667205 @default.
- W2015514443 cites W1971599681 @default.
- W2015514443 cites W1976065233 @default.
- W2015514443 cites W1994248925 @default.
- W2015514443 cites W2025868923 @default.
- W2015514443 cites W2033406104 @default.
- W2015514443 cites W2035530452 @default.
- W2015514443 cites W2044172001 @default.
- W2015514443 cites W2045387957 @default.
- W2015514443 cites W2054248950 @default.
- W2015514443 cites W2066494763 @default.
- W2015514443 cites W2094721375 @default.
- W2015514443 cites W30395697 @default.
- W2015514443 doi "https://doi.org/10.1097/00000542-200503000-00026" @default.
- W2015514443 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15731606" @default.
- W2015514443 hasPublicationYear "2005" @default.
- W2015514443 type Work @default.
- W2015514443 sameAs 2015514443 @default.
- W2015514443 citedByCount "36" @default.
- W2015514443 countsByYear W20155144432013 @default.
- W2015514443 countsByYear W20155144432014 @default.
- W2015514443 countsByYear W20155144432015 @default.
- W2015514443 countsByYear W20155144432016 @default.
- W2015514443 countsByYear W20155144432017 @default.
- W2015514443 countsByYear W20155144432020 @default.
- W2015514443 crossrefType "journal-article" @default.
- W2015514443 hasAuthorship W2015514443A5010573384 @default.
- W2015514443 hasAuthorship W2015514443A5041649938 @default.
- W2015514443 hasAuthorship W2015514443A5046179971 @default.
- W2015514443 hasAuthorship W2015514443A5066276345 @default.
- W2015514443 hasConcept C126322002 @default.
- W2015514443 hasConcept C141071460 @default.
- W2015514443 hasConcept C14184104 @default.
- W2015514443 hasConcept C157820659 @default.
- W2015514443 hasConcept C2776572635 @default.
- W2015514443 hasConcept C2780269707 @default.
- W2015514443 hasConcept C2780580376 @default.
- W2015514443 hasConcept C2780852908 @default.
- W2015514443 hasConcept C2781328992 @default.
- W2015514443 hasConcept C2992037949 @default.
- W2015514443 hasConcept C42219234 @default.
- W2015514443 hasConcept C44249647 @default.
- W2015514443 hasConcept C71924100 @default.
- W2015514443 hasConceptScore W2015514443C126322002 @default.
- W2015514443 hasConceptScore W2015514443C141071460 @default.
- W2015514443 hasConceptScore W2015514443C14184104 @default.
- W2015514443 hasConceptScore W2015514443C157820659 @default.
- W2015514443 hasConceptScore W2015514443C2776572635 @default.
- W2015514443 hasConceptScore W2015514443C2780269707 @default.
- W2015514443 hasConceptScore W2015514443C2780580376 @default.
- W2015514443 hasConceptScore W2015514443C2780852908 @default.
- W2015514443 hasConceptScore W2015514443C2781328992 @default.
- W2015514443 hasConceptScore W2015514443C2992037949 @default.
- W2015514443 hasConceptScore W2015514443C42219234 @default.
- W2015514443 hasConceptScore W2015514443C44249647 @default.
- W2015514443 hasConceptScore W2015514443C71924100 @default.
- W2015514443 hasIssue "3" @default.
- W2015514443 hasLocation W20155144431 @default.
- W2015514443 hasLocation W20155144432 @default.
- W2015514443 hasOpenAccess W2015514443 @default.
- W2015514443 hasPrimaryLocation W20155144431 @default.
- W2015514443 hasRelatedWork W1528629345 @default.
- W2015514443 hasRelatedWork W2028492676 @default.
- W2015514443 hasRelatedWork W2035530452 @default.
- W2015514443 hasRelatedWork W2066494763 @default.
- W2015514443 hasRelatedWork W2161235316 @default.
- W2015514443 hasRelatedWork W2369321864 @default.
- W2015514443 hasRelatedWork W2379902739 @default.
- W2015514443 hasRelatedWork W3155076336 @default.
- W2015514443 hasRelatedWork W4231164120 @default.
- W2015514443 hasRelatedWork W4312260308 @default.
- W2015514443 hasVolume "102" @default.
- W2015514443 isParatext "false" @default.
- W2015514443 isRetracted "false" @default.
- W2015514443 magId "2015514443" @default.
- W2015514443 workType "article" @default.