FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015561964> ?p ?o ?g. }

• W2015561964 endingPage "599" @default.
• W2015561964 startingPage "593" @default.
• W2015561964 abstract "Using an enzyme-linked immunosorbent assay (ELISA) technique, we measured the soluble interleukin 2 receptor (s-IL-2R) levels in the sera of patients with adult T-cell leukemia (ATL) in Japan. The s-IL-2R levels in the sera of the ATL patients were markedly higher (range 540-310, 400 U/ml, mean +/- SD = 62,800 +/- 81,000 U/ml, n = 42) than those in normal individuals (range 42-950 U/ml, mean +/- SD = 322 +/- 198 U/ml, n = 35, P less than 0.01). The patients with acute-type or lymphoma-type ATL had high s-IL-2R levels (range 11,900-310,400 U/ml, mean +/- SD = 110,340 +/- 370 U/ml, n = 15; range 26,400-214,400 U/ml, mean +/- SD = 90,170 +/- 59,040 U/ml, n = 7, respectively). All of the patients with hypercalcemia (Ca greater than 10 mg/dl) or elevated serum LDH levels (LDH greater than 500 IU/liter) also had s-IL-2R levels above 10,000 U/ml. The high s-IL-2R levels in the sera of ATL patients indicate abnormal IL-2 receptor production and its release from the leukemic cells in vivo. Thus, the serum s-IL-2R level may be a sensitive and useful marker to monitor the total amount of tumor cells in ATL, especially in the lymphoma type. We next examined the serum s-IL-2R levels in human T-cell leukemia/lymphoma virus type-I (HTLV-I) seropositive healthy carriers to investigate whether there might be abnormal IL-2 receptor expression in such individuals. However, there was no statistically significant difference between the s-IL-2R level of 71 HTLV-I seropositive healthy carriers (range 65-880 U/ml, mean +/- SD = 394 +/- 212 U/ml) and that of 71 age- and sex-matched normal individuals (range 33-950 U/ml, mean +/- SD = 357 +/- 224 U/ml) who lived in Okinawa Prefecture." @default.
• W2015561964 created "2016-06-24" @default.
• W2015561964 creator A5015338865 @default.
• W2015561964 creator A5021248501 @default.
• W2015561964 creator A5058195549 @default.
• W2015561964 creator A5063819703 @default.
• W2015561964 creator A5065881970 @default.
• W2015561964 date "1988-05-01" @default.
• W2015561964 modified "2023-09-27" @default.
• W2015561964 title "Serum Soluble Interleukin-2 Receptor Levels in Patients with Adult T-cell Leukemia and Human T-cell Leukemia/Lymphoma Virus Type-I Seropositive Healthy Carriers" @default.
• W2015561964 cites W1512843295 @default.
• W2015561964 cites W1540459294 @default.
• W2015561964 cites W1552516114 @default.
• W2015561964 cites W1575437053 @default.
• W2015561964 cites W1991049176 @default.
• W2015561964 cites W2025704167 @default.
• W2015561964 cites W2041646069 @default.
• W2015561964 cites W2048022927 @default.
• W2015561964 cites W2065141696 @default.
• W2015561964 cites W2071592765 @default.
• W2015561964 cites W2084455176 @default.
• W2015561964 cites W2085419556 @default.
• W2015561964 cites W2086143621 @default.
• W2015561964 cites W2103138806 @default.
• W2015561964 cites W2105888542 @default.
• W2015561964 cites W2112530262 @default.
• W2015561964 cites W2120274247 @default.
• W2015561964 cites W2155826396 @default.
• W2015561964 cites W2262549231 @default.
• W2015561964 cites W2336865896 @default.
• W2015561964 cites W2395185936 @default.
• W2015561964 cites W2398282778 @default.
• W2015561964 cites W2412732001 @default.
• W2015561964 cites W2484759161 @default.
• W2015561964 cites W4250178961 @default.
• W2015561964 cites W4254544684 @default.
• W2015561964 cites W70141626 @default.
• W2015561964 cites W1027509826 @default.
• W2015561964 cites W2136249773 @default.
• W2015561964 doi "https://doi.org/10.1111/j.1349-7006.1988.tb00028.x" @default.
• W2015561964 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5917554" @default.
• W2015561964 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2900231" @default.
• W2015561964 hasPublicationYear "1988" @default.
• W2015561964 type Work @default.
• W2015561964 sameAs 2015561964 @default.
• W2015561964 citedByCount "32" @default.
• W2015561964 countsByYear W20155619642013 @default.
• W2015561964 countsByYear W20155619642015 @default.
• W2015561964 countsByYear W20155619642017 @default.
• W2015561964 countsByYear W20155619642018 @default.
• W2015561964 countsByYear W20155619642020 @default.
• W2015561964 countsByYear W20155619642021 @default.
• W2015561964 crossrefType "journal-article" @default.
• W2015561964 hasAuthorship W2015561964A5015338865 @default.
• W2015561964 hasAuthorship W2015561964A5021248501 @default.
• W2015561964 hasAuthorship W2015561964A5058195549 @default.
• W2015561964 hasAuthorship W2015561964A5063819703 @default.
• W2015561964 hasAuthorship W2015561964A5065881970 @default.
• W2015561964 hasBestOaLocation W20155619642 @default.
• W2015561964 hasConcept C126322002 @default.
• W2015561964 hasConcept C134018914 @default.
• W2015561964 hasConcept C170493617 @default.
• W2015561964 hasConcept C176674119 @default.
• W2015561964 hasConcept C203014093 @default.
• W2015561964 hasConcept C2776913467 @default.
• W2015561964 hasConcept C2777371288 @default.
• W2015561964 hasConcept C2778461978 @default.
• W2015561964 hasConcept C2779338263 @default.
• W2015561964 hasConcept C2780815077 @default.
• W2015561964 hasConcept C71924100 @default.
• W2015561964 hasConcept C90924648 @default.
• W2015561964 hasConceptScore W2015561964C126322002 @default.
• W2015561964 hasConceptScore W2015561964C134018914 @default.
• W2015561964 hasConceptScore W2015561964C170493617 @default.
• W2015561964 hasConceptScore W2015561964C176674119 @default.
• W2015561964 hasConceptScore W2015561964C203014093 @default.
• W2015561964 hasConceptScore W2015561964C2776913467 @default.
• W2015561964 hasConceptScore W2015561964C2777371288 @default.
• W2015561964 hasConceptScore W2015561964C2778461978 @default.
• W2015561964 hasConceptScore W2015561964C2779338263 @default.
• W2015561964 hasConceptScore W2015561964C2780815077 @default.
• W2015561964 hasConceptScore W2015561964C71924100 @default.
• W2015561964 hasConceptScore W2015561964C90924648 @default.
• W2015561964 hasIssue "5" @default.
• W2015561964 hasLocation W20155619641 @default.
• W2015561964 hasLocation W20155619642 @default.
• W2015561964 hasLocation W20155619643 @default.
• W2015561964 hasLocation W20155619644 @default.
• W2015561964 hasOpenAccess W2015561964 @default.
• W2015561964 hasPrimaryLocation W20155619641 @default.
• W2015561964 hasRelatedWork W1888111113 @default.
• W2015561964 hasRelatedWork W1997676430 @default.
• W2015561964 hasRelatedWork W2015561964 @default.
• W2015561964 hasRelatedWork W2032965398 @default.
• W2015561964 hasRelatedWork W2034583712 @default.
• W2015561964 hasRelatedWork W2063619316 @default.
• W2015561964 hasRelatedWork W2088821386 @default.
• W2015561964 hasRelatedWork W2103980266 @default.

• next