FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015574037> ?p ?o ?g. }

• W2015574037 endingPage "234" @default.
• W2015574037 startingPage "224" @default.
• W2015574037 abstract "The hallmark of the arthropods is their segmented body, although origin of segmentation, however, is unresolved. In order to shed light on the origin of segmentation we investigated orthologs of pair rule genes (PRGs) and segment polarity genes (SPGs) in a member of the closest related sister-group to the arthropods, the onychophorans. Our gene expression data analysis suggests that most of the onychophoran PRGs do not play a role in segmentation. One possible exception is the even-skipped (eve) gene that is expressed in the posterior end of the onychophoran where new segments are likely patterned, and is also expressed in segmentation-gene typical transverse stripes in at least a number of newly formed segments. Other onychophoran PRGs such as runt (run), hairy/Hes (h/Hes) and odd-skipped (odd) do not appear to have a function in segmentation at all. Onychophoran PRGs that act low in the segmentation gene cascade in insects, however, are potentially involved in segment-patterning. Most obvious is that from the expression of the pairberry (pby) gene ortholog that is expressed in a typical SPG-pattern. Since this result suggested possible conservation of the SPG-network we further investigated SPGs (and associated factors) such as Notum in the onychophoran. We find that the expression patterns of SPGs in arthropods and the onychophoran are highly conserved, suggesting a conserved SPG-network in these two clades, and indeed also in an annelid. This may suggest that the common ancestor of lophotrochozoans and ecdysozoans was already segmented utilising the same SPG-network, or that the SPG-network was recruited independently in annelids and onychophorans/arthropods." @default.
• W2015574037 created "2016-06-24" @default.
• W2015574037 creator A5068768940 @default.
• W2015574037 creator A5090256243 @default.
• W2015574037 date "2013-10-01" @default.
• W2015574037 modified "2023-10-12" @default.
• W2015574037 title "Deciphering the onychophoran ‘segmentation gene cascade’: Gene expression reveals limited involvement of pair rule gene orthologs in segmentation, but a highly conserved segment polarity gene network" @default.
• W2015574037 cites W1649982107 @default.
• W2015574037 cites W1772672315 @default.
• W2015574037 cites W1815472980 @default.
• W2015574037 cites W1869366780 @default.
• W2015574037 cites W1943532060 @default.
• W2015574037 cites W1964943774 @default.
• W2015574037 cites W1967497547 @default.
• W2015574037 cites W1972352539 @default.
• W2015574037 cites W1975380397 @default.
• W2015574037 cites W1975420952 @default.
• W2015574037 cites W1979259492 @default.
• W2015574037 cites W1980719358 @default.
• W2015574037 cites W1981708895 @default.
• W2015574037 cites W1987142041 @default.
• W2015574037 cites W1987366641 @default.
• W2015574037 cites W1989117766 @default.
• W2015574037 cites W1990944246 @default.
• W2015574037 cites W1993838585 @default.
• W2015574037 cites W1994245587 @default.
• W2015574037 cites W1994746388 @default.
• W2015574037 cites W1997545186 @default.
• W2015574037 cites W1997882261 @default.
• W2015574037 cites W2000572318 @default.
• W2015574037 cites W2001959741 @default.
• W2015574037 cites W2002809491 @default.
• W2015574037 cites W2011007930 @default.
• W2015574037 cites W2022919281 @default.
• W2015574037 cites W2027495975 @default.
• W2015574037 cites W2029669415 @default.
• W2015574037 cites W2034161528 @default.
• W2015574037 cites W2038008442 @default.
• W2015574037 cites W2039038180 @default.
• W2015574037 cites W2039127205 @default.
• W2015574037 cites W2041313345 @default.
• W2015574037 cites W2042494430 @default.
• W2015574037 cites W2044984965 @default.
• W2015574037 cites W2049338893 @default.
• W2015574037 cites W2053320483 @default.
• W2015574037 cites W2053676247 @default.
• W2015574037 cites W2053850816 @default.
• W2015574037 cites W2054216558 @default.
• W2015574037 cites W2054838412 @default.
• W2015574037 cites W2059326396 @default.
• W2015574037 cites W2060520959 @default.
• W2015574037 cites W2061364925 @default.
• W2015574037 cites W2061883669 @default.
• W2015574037 cites W2062235108 @default.
• W2015574037 cites W2064546612 @default.
• W2015574037 cites W2067284166 @default.
• W2015574037 cites W2068760238 @default.
• W2015574037 cites W2075154859 @default.
• W2015574037 cites W2077341997 @default.
• W2015574037 cites W2085405921 @default.
• W2015574037 cites W2090783510 @default.
• W2015574037 cites W2095728733 @default.
• W2015574037 cites W2097382368 @default.
• W2015574037 cites W2103526067 @default.
• W2015574037 cites W2108345995 @default.
• W2015574037 cites W2109723121 @default.
• W2015574037 cites W2111546844 @default.
• W2015574037 cites W2116212202 @default.
• W2015574037 cites W2126536695 @default.
• W2015574037 cites W2131708396 @default.
• W2015574037 cites W2134510799 @default.
• W2015574037 cites W2135210361 @default.
• W2015574037 cites W2141269843 @default.
• W2015574037 cites W2141890905 @default.
• W2015574037 cites W2143210482 @default.
• W2015574037 cites W2143503284 @default.
• W2015574037 cites W2153261864 @default.
• W2015574037 cites W2155409938 @default.
• W2015574037 cites W2156841387 @default.
• W2015574037 cites W2158295165 @default.
• W2015574037 cites W2158714788 @default.
• W2015574037 cites W2160969485 @default.
• W2015574037 cites W2164997158 @default.
• W2015574037 cites W2165795986 @default.
• W2015574037 cites W2166039615 @default.
• W2015574037 cites W2168149321 @default.
• W2015574037 cites W4246395620 @default.
• W2015574037 doi "https://doi.org/10.1016/j.ydbio.2013.07.010" @default.
• W2015574037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23880430" @default.
• W2015574037 hasPublicationYear "2013" @default.
• W2015574037 type Work @default.
• W2015574037 sameAs 2015574037 @default.
• W2015574037 citedByCount "65" @default.
• W2015574037 countsByYear W20155740372014 @default.
• W2015574037 countsByYear W20155740372015 @default.
• W2015574037 countsByYear W20155740372016 @default.
• W2015574037 countsByYear W20155740372017 @default.
• W2015574037 countsByYear W20155740372018 @default.

• next