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• W2015582001 abstract "Phosphorylcholine is one of the major epitopes of oxidised low density lipoprotein. Low levels of IgM antibodies against phosphorylcholine (anti-PC) are associated with development of myocardial infarction and stroke. It has been shown that patients with Alzheimer’s disease and other dementias have significantly lower serum anti-PC levels compared to controls, suggesting that low levels of atheroprotective anti-PC may play a role in AD and dementia. We quantified levels of anti-PC levels using an ELISA in plasma from 176 controls, 125 patients with Alzheimer’s disease, 19 patients with vascular dementia and 63 patients with other dementias. We observed similar plasma anti-PC levels in controls, patients with Alzheimer’s disease, and other dementias. Our data suggests that anti-PC is not useful as a biomarker for Alzheimer’s disease." @default.
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• W2015582001 date "2015-02-05" @default.
• W2015582001 modified "2023-10-16" @default.
• W2015582001 title "Antibodies against phosphorylcholine are not altered in plasma of patients with Alzheimer’s disease" @default.
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• W2015582001 doi "https://doi.org/10.1186/s12883-015-0260-1" @default.
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