Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015588448> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2015588448 endingPage "71" @default.
- W2015588448 startingPage "67" @default.
- W2015588448 abstract "Red cell bound IgM autoantibodies free of associated IgG autoantibodies and unable to activate complement have not yet been considered as the cause of autoimmune haemolytic anaemia (AIHA). We report on warm type AIHA resulting from the action of IgM autoantibodies on circulating RBC. Twelve children (eight of whom were infants) with relatively severe haemolytic anaemia were studied. Whereas the clinical findings and courses of all children appeared to be compatible with warm type AIHA, the serological findings during the haemolytic phase were atypical in that the direct antiglobulin test (DAT) was negative in 11, and positive in one case due to C3d only. The use of radiolabelled antihuman globulin antibodies showed, however, that the RBC of all the patients were sensitized with warm IgM antibodies. Elevated values of IgA and/or IgG immunoglobulins on the patients’ RBC were found to be present in only two cases. Complement activation by IgM autoantibodies could not be detected in all other cases neither in vivo nor in vitro. Thus, we conclude that non-complement binding IgM autoantibodies were responsible for the AIHA in the majority of these children possibly representing an as yet unrecognized variant of warm type AIHA." @default.
- W2015588448 created "2016-06-24" @default.
- W2015588448 creator A5001548323 @default.
- W2015588448 creator A5043761531 @default.
- W2015588448 date "1987-01-01" @default.
- W2015588448 modified "2023-10-16" @default.
- W2015588448 title "Autoimmune haemolytic anaemia in childhood associated with non-complement binding IgM autoantibodies" @default.
- W2015588448 cites W1578980478 @default.
- W2015588448 cites W1983649348 @default.
- W2015588448 cites W1985368720 @default.
- W2015588448 cites W1989715897 @default.
- W2015588448 cites W1990101133 @default.
- W2015588448 cites W1995917446 @default.
- W2015588448 cites W2000680139 @default.
- W2015588448 cites W2002880428 @default.
- W2015588448 cites W2041909852 @default.
- W2015588448 cites W2043323340 @default.
- W2015588448 cites W2048919792 @default.
- W2015588448 cites W2052432440 @default.
- W2015588448 cites W2054654944 @default.
- W2015588448 cites W2054923231 @default.
- W2015588448 cites W2069695930 @default.
- W2015588448 cites W2070896221 @default.
- W2015588448 cites W2075322288 @default.
- W2015588448 cites W2085649019 @default.
- W2015588448 cites W2095114611 @default.
- W2015588448 cites W2125000259 @default.
- W2015588448 cites W2161784847 @default.
- W2015588448 cites W2264681400 @default.
- W2015588448 cites W2335892452 @default.
- W2015588448 cites W2337520228 @default.
- W2015588448 cites W2405595600 @default.
- W2015588448 cites W2430137773 @default.
- W2015588448 doi "https://doi.org/10.1111/j.1365-2141.1987.tb06137.x" @default.
- W2015588448 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3814527" @default.
- W2015588448 hasPublicationYear "1987" @default.
- W2015588448 type Work @default.
- W2015588448 sameAs 2015588448 @default.
- W2015588448 citedByCount "34" @default.
- W2015588448 countsByYear W20155884482014 @default.
- W2015588448 countsByYear W20155884482015 @default.
- W2015588448 countsByYear W20155884482017 @default.
- W2015588448 countsByYear W20155884482019 @default.
- W2015588448 countsByYear W20155884482021 @default.
- W2015588448 countsByYear W20155884482022 @default.
- W2015588448 crossrefType "journal-article" @default.
- W2015588448 hasAuthorship W2015588448A5001548323 @default.
- W2015588448 hasAuthorship W2015588448A5043761531 @default.
- W2015588448 hasConcept C111684460 @default.
- W2015588448 hasConcept C159654299 @default.
- W2015588448 hasConcept C163764329 @default.
- W2015588448 hasConcept C203014093 @default.
- W2015588448 hasConcept C2776553844 @default.
- W2015588448 hasConcept C2777385706 @default.
- W2015588448 hasConcept C2778986270 @default.
- W2015588448 hasConcept C2780898057 @default.
- W2015588448 hasConcept C45189115 @default.
- W2015588448 hasConcept C71924100 @default.
- W2015588448 hasConceptScore W2015588448C111684460 @default.
- W2015588448 hasConceptScore W2015588448C159654299 @default.
- W2015588448 hasConceptScore W2015588448C163764329 @default.
- W2015588448 hasConceptScore W2015588448C203014093 @default.
- W2015588448 hasConceptScore W2015588448C2776553844 @default.
- W2015588448 hasConceptScore W2015588448C2777385706 @default.
- W2015588448 hasConceptScore W2015588448C2778986270 @default.
- W2015588448 hasConceptScore W2015588448C2780898057 @default.
- W2015588448 hasConceptScore W2015588448C45189115 @default.
- W2015588448 hasConceptScore W2015588448C71924100 @default.
- W2015588448 hasIssue "1" @default.
- W2015588448 hasLocation W20155884481 @default.
- W2015588448 hasLocation W20155884482 @default.
- W2015588448 hasOpenAccess W2015588448 @default.
- W2015588448 hasPrimaryLocation W20155884481 @default.
- W2015588448 hasRelatedWork W14811444 @default.
- W2015588448 hasRelatedWork W1982291363 @default.
- W2015588448 hasRelatedWork W2015588448 @default.
- W2015588448 hasRelatedWork W2020809624 @default.
- W2015588448 hasRelatedWork W2099244599 @default.
- W2015588448 hasRelatedWork W2105300830 @default.
- W2015588448 hasRelatedWork W2276225114 @default.
- W2015588448 hasRelatedWork W3110097208 @default.
- W2015588448 hasRelatedWork W4255212423 @default.
- W2015588448 hasRelatedWork W3154382827 @default.
- W2015588448 hasVolume "65" @default.
- W2015588448 isParatext "false" @default.
- W2015588448 isRetracted "false" @default.
- W2015588448 magId "2015588448" @default.
- W2015588448 workType "article" @default.