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- W2015610080 abstract "Prostacyclin synthase (PGIS) is the final committed enzymatic step in the pathway of prostacyclin (PGI2) production, occurring at a branch point where substrate (PGH2) can be directed either toward prostacyclin, which affords protection, or thromboxane, which augments injury. The imbalance of prostacyclin and thromboxane is involved in the pathogenesis of several diseases, such as pulmonary hypertension, acute lung injury, and atherosclerosis. These studies were designed to pursue the molecular cloning and characterization of rat prostacyclin synthase." @default.
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- W2015610080 date "1997-06-01" @default.
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- W2015610080 title "Rat Prostacyclin Synthase" @default.
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