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• W2015616694 abstract "Single cells in genetically homogeneous microbial cultures exhibit marked phenotypic heterogeneity that is considered to bolster the fitness of the whole population. Heterogeneity on the single-cell level is typically masked in conventional studies of microbial populations, which rely on data averaged across thousands or millions of cells in a sample. Here we introduce confocal Raman microspectroscopy as a method for investigating and illustrating the spatial heterogeneity of microbial cell populations. By the use of three different test organisms as model systems, we show pronounced cellular heterogeneity even in colonies cultivated under laboratory conditions." @default.
• W2015616694 created "2016-06-24" @default.
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• W2015616694 date "2009-01-01" @default.
• W2015616694 modified "2023-10-02" @default.
• W2015616694 title "Phenotypic heterogeneity within microbial populations at the single-cell level investigated by confocal Raman microspectroscopy" @default.
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• W2015616694 doi "https://doi.org/10.1039/b822574e" @default.
• W2015616694 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19475141" @default.
• W2015616694 hasPublicationYear "2009" @default.
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