Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015634978> ?p ?o ?g. }
- W2015634978 endingPage "281" @default.
- W2015634978 startingPage "272" @default.
- W2015634978 abstract "We investigated clinical effects of intracoronary transplantation of CD34+ cells in patients with dilated cardiomyopathy (DCM).Of 55 patients with DCM, 28 were randomized to CD34+ transplantation (SC group), and 27 patients did not receive stem cell therapy (controls). In the SC group, peripheral blood CD34+ cells were mobilized by granulocyte-colony stimulating factor and collected via apheresis. Patients underwent myocardial scintigraphy and CD34+ cells were injected in the coronary artery supplying the segments with reduced viability.At baseline, the 2 groups did not differ in age, gender, left ventricular ejection fraction (LVEF), or NT-proBNP levels. At 1 year, stem cell therapy was associated with an increase in LVEF (from 25.5 ± 7.5% to 30.1 ± 6.7%; P = .03), an increase in 6-minute walk distance (from 359 ± 104 m to 485 ± 127 m; P = .001), and a decrease in NT-proBNP (from 2069 ± 1996 pg/mL to 1037 ± 950 pg/mL; P = .01). The secondary endpoint of 1-year mortality or heart transplantation was lower in patients receiving SC therapy (2/28, 7%) than in controls (8/27, 30%) (P = .03), and SC therapy was the only independent predictor of outcome on multivariable analysis (P = .04).Intracoronary stem cell transplantation could lead to improved ventricular remodeling, better exercise tolerance and potentially improved survival in patients with DCM." @default.
- W2015634978 created "2016-06-24" @default.
- W2015634978 creator A5001067636 @default.
- W2015634978 creator A5004340496 @default.
- W2015634978 creator A5018097588 @default.
- W2015634978 creator A5033482985 @default.
- W2015634978 creator A5067476985 @default.
- W2015634978 creator A5071926235 @default.
- W2015634978 creator A5084630029 @default.
- W2015634978 creator A5084952036 @default.
- W2015634978 date "2011-04-01" @default.
- W2015634978 modified "2023-10-18" @default.
- W2015634978 title "Effects of Intracoronary Stem Cell Transplantation in Patients With Dilated Cardiomyopathy" @default.
- W2015634978 cites W1539156414 @default.
- W2015634978 cites W1991374176 @default.
- W2015634978 cites W1995153346 @default.
- W2015634978 cites W1999718698 @default.
- W2015634978 cites W2009485059 @default.
- W2015634978 cites W2023954442 @default.
- W2015634978 cites W2026773500 @default.
- W2015634978 cites W2056834741 @default.
- W2015634978 cites W2067149824 @default.
- W2015634978 cites W2081944008 @default.
- W2015634978 cites W2098892229 @default.
- W2015634978 cites W2106673834 @default.
- W2015634978 cites W2109680555 @default.
- W2015634978 cites W2122984949 @default.
- W2015634978 cites W2123163588 @default.
- W2015634978 cites W2138264396 @default.
- W2015634978 cites W2140956046 @default.
- W2015634978 cites W2156724821 @default.
- W2015634978 cites W2159869836 @default.
- W2015634978 cites W2546926805 @default.
- W2015634978 cites W31463575 @default.
- W2015634978 cites W4251403705 @default.
- W2015634978 doi "https://doi.org/10.1016/j.cardfail.2010.11.007" @default.
- W2015634978 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21440864" @default.
- W2015634978 hasPublicationYear "2011" @default.
- W2015634978 type Work @default.
- W2015634978 sameAs 2015634978 @default.
- W2015634978 citedByCount "97" @default.
- W2015634978 countsByYear W20156349782012 @default.
- W2015634978 countsByYear W20156349782013 @default.
- W2015634978 countsByYear W20156349782014 @default.
- W2015634978 countsByYear W20156349782015 @default.
- W2015634978 countsByYear W20156349782016 @default.
- W2015634978 countsByYear W20156349782017 @default.
- W2015634978 countsByYear W20156349782018 @default.
- W2015634978 countsByYear W20156349782019 @default.
- W2015634978 countsByYear W20156349782020 @default.
- W2015634978 countsByYear W20156349782021 @default.
- W2015634978 countsByYear W20156349782022 @default.
- W2015634978 countsByYear W20156349782023 @default.
- W2015634978 crossrefType "journal-article" @default.
- W2015634978 hasAuthorship W2015634978A5001067636 @default.
- W2015634978 hasAuthorship W2015634978A5004340496 @default.
- W2015634978 hasAuthorship W2015634978A5018097588 @default.
- W2015634978 hasAuthorship W2015634978A5033482985 @default.
- W2015634978 hasAuthorship W2015634978A5067476985 @default.
- W2015634978 hasAuthorship W2015634978A5071926235 @default.
- W2015634978 hasAuthorship W2015634978A5084630029 @default.
- W2015634978 hasAuthorship W2015634978A5084952036 @default.
- W2015634978 hasConcept C10205521 @default.
- W2015634978 hasConcept C126322002 @default.
- W2015634978 hasConcept C164705383 @default.
- W2015634978 hasConcept C168563851 @default.
- W2015634978 hasConcept C203092338 @default.
- W2015634978 hasConcept C2775932942 @default.
- W2015634978 hasConcept C2776383484 @default.
- W2015634978 hasConcept C2776694085 @default.
- W2015634978 hasConcept C2776738589 @default.
- W2015634978 hasConcept C2776863835 @default.
- W2015634978 hasConcept C2777767877 @default.
- W2015634978 hasConcept C2778198053 @default.
- W2015634978 hasConcept C2778425758 @default.
- W2015634978 hasConcept C2778797674 @default.
- W2015634978 hasConcept C2778849806 @default.
- W2015634978 hasConcept C2779050716 @default.
- W2015634978 hasConcept C2779389132 @default.
- W2015634978 hasConcept C28328180 @default.
- W2015634978 hasConcept C2911091166 @default.
- W2015634978 hasConcept C500558357 @default.
- W2015634978 hasConcept C54355233 @default.
- W2015634978 hasConcept C71924100 @default.
- W2015634978 hasConcept C78085059 @default.
- W2015634978 hasConcept C86803240 @default.
- W2015634978 hasConcept C89560881 @default.
- W2015634978 hasConceptScore W2015634978C10205521 @default.
- W2015634978 hasConceptScore W2015634978C126322002 @default.
- W2015634978 hasConceptScore W2015634978C164705383 @default.
- W2015634978 hasConceptScore W2015634978C168563851 @default.
- W2015634978 hasConceptScore W2015634978C203092338 @default.
- W2015634978 hasConceptScore W2015634978C2775932942 @default.
- W2015634978 hasConceptScore W2015634978C2776383484 @default.
- W2015634978 hasConceptScore W2015634978C2776694085 @default.
- W2015634978 hasConceptScore W2015634978C2776738589 @default.
- W2015634978 hasConceptScore W2015634978C2776863835 @default.
- W2015634978 hasConceptScore W2015634978C2777767877 @default.