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- W2015665323 abstract "We report the first 2 genetically confirmed cases of primary renal sclerosing epithelioid fibrosarcoma (SEF), occurring in a 17-year-old boy and a 61-year-old woman. In both cases, the tumors demonstrated the typical epithelioid clear cell morphology associated with extensive hyalinizing fibrosis, raising the differential diagnosis of solitary fibrous tumor, metanephric stromal tumor, and the sclerosing variant of clear cell sarcoma of the kidney. Both neoplasms demonstrated diffuse immunoreactivity for MUC4, a highly specific marker for SEF, and both demonstrated evidence of rearrangement of both the EWSR1 and CREB3L1 genes, which have recently been shown to be fused in this entity. Both neoplasms presented with metastatic disease. Primary renal SEF represents yet another translocation-associated sarcoma now shown to arise primarily in the kidney." @default.
- W2015665323 created "2016-06-24" @default.
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- W2015665323 date "2015-03-01" @default.
- W2015665323 modified "2023-10-09" @default.
- W2015665323 title "Primary Renal Sclerosing Epithelioid Fibrosarcoma" @default.
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- W2015665323 doi "https://doi.org/10.1097/pas.0000000000000338" @default.
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